Results 51 to 60 of about 11,766 (177)

Disease Remission: A Scoping Review With Thematic Analysis of the Scientific Literature With Implications for Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, Volume 16, Issue 6, Page 615-629, June 2026.
ABSTRACT Background Remission, a term used to describe a goal of treatment for some chronic diseases, has recently been proposed for chronic rhinosinusitis (CRS). However, it is unclear what remission means for CRS and why it should serve as a goal in the present‐day treatment of CRS.
Nikhil Parail, Lynn Warner, Stacey T. Gray, Claire Hopkins, Peter H. Hwang, Sarah K. Wise, Katie M. Phillips, Ahmad R. Sedaghat   +7 more
wiley   +1 more source

Methotrexate Toxicity in a Patient With Renal Failure Despite a Normal Methotrexate Concentration: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Methotrexate (MTX) is a folate antagonist widely used as a disease‐modifying antirheumatic drug (DMARD) in rheumatoid arthritis (RA), as well as in several malignancies and autoimmune disorders. Although low‐dose MTX (5–20 mg/week) is generally considered safe, it has a narrow therapeutic index, and toxicity can occur even at therapeutic doses,
Fatemeh Afra, Mahshad Ghoddusi, Mahsa Mottahedi, Maryam Albaji, Samira Kafan, Roya Saedpanah, Amir Shokri, Elham Nazar   +7 more
wiley   +1 more source

Caplacizumab in the Treatment of Patients with Recurrent Thrombotic Thrombocytopenic Purpura (TTP) [PDF]

Documenta Haematologica
We report two cases of recurrent thrombotic thrombocytopenic purpura, both patients without significant personal pathological antecedents, in which the evolution was favorable following the association of Caplacizumab with the classic treatment with ...
Mihaela-Sabrina HERDEA, Adela-Sara IONESCU, Oana PATRINOIU, Mihaela ANDREESCU   +3 more
doaj   +1 more source

Catastrophic Antiphospholipid Syndrome in a Young Female Complicated by Systemic Lupus Erythematosus and Left Atrial Myxoma: A Rare Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Catastrophic antiphospholipid syndrome (CAPS) is a fulminant and rare variant of antiphospholipid syndrome characterized by rapidly progressive multiorgan thrombosis and a high mortality rate. Its diagnosis is often challenging due to overlapping clinical features with sepsis, thromboembolic disorders, and systemic autoimmune diseases.
Nazmin Ahmed, Mohammad Nazrul Hossain, Abdullah Salman, Sabrina Yesmin, S. M. G. Saklayen   +4 more
wiley   +1 more source

Diagnosis of thrombotic thrombocytopenic purpura

Terapevticheskii arkhiv, 2020
Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening disease, disease, characterised by microangiopathic hemolytic anaemia, consumption thrombocytopenia, and organ dysfunction. The pathogenesis of TTP is attributed to the deficiency in the activity of the metalloproteinase ADAMTS13, specific von Willebrand factor cleaving protease. TTP
G. M. Galstyan, E. E. Klebanova
openaire   +4 more sources

Fulminant myocarditis in immune‐mediated thrombotic thrombocytopenic purpura: A case report

Acute Medicine & Surgery
Background Thrombotic thrombocytopenic purpura is a life‐threatening thrombotic microangiopathy characterized by systemic microvascular thrombosis. Cardiovascular complications, including myocardial ischemia and necrosis, are a leading cause of acute ...
Haruka Ishikita, Akira Endo, Keisuke Suzuki, Tomohiro Akutsu, Yuichi Araki, Koji Morishita   +5 more
doaj   +1 more source

The need for dried plasma—Still a national issue: Where are we and recommendations

Transfusion, EarlyView.
Anthony E. Pusateri, Shibani Pati, Toby A. Silverman, Roman Dudaryk, Joseph F. Rappold, Lisa Buckley, Andrew P. Cap, Jose A. Cancelas, Laurence M. Corash, G. Michael Fitzpatrick, Michael Ganio, Adam Gerber, Richard Gonzales, Jennifer M. Gurney, Ernest E. Moore, Hunter B. Moore, Vijay Nair, Michael Policastro, Travis M. Polk, Jeffrey W. Shupp, Jason L. Sperry, Ralph R. Vassallo, Therese A. West, John B. Holcomb, Lester Martinez‐Lopez   +24 more
wiley   +1 more source

Pediatric Therapeutic Plasma Exchange: Characterization of Practice, Epidemiology, and Safety Profile at a Children's Hospital in the United States

Journal of Clinical Apheresis, Volume 41, Issue 3, June 2026.
ABSTRACT There is a need to better understand the indications and safety profiles for therapeutic plasma exchange (TPE) in children. We aimed to assess pediatric TPE practice at a large academic center by retrospective chart review from 2011 to 2022. Patient demographics and clinical information including American Society for Apheresis (ASFA) category ...
Benjamin C. Lee, Brian D. Adkins, Ayda Javanbakht, Hung S. Luu, Daniel K. Noland   +4 more
wiley   +1 more source

Sunitinib Induced Thrombotic Thrombocytopenic Purpura in addition to Severe Hypothyroidism: A Case Report and Review of the Literature

Case Reports in Medicine, 2014
Introduction. Sunitinib malate is an oral multitargeting tyrosine kinase inhibitor approved for the first line treatment of metastatic renal cell carcinoma.
Imane El Dika, Deborah Mukherji, Sally Temraz, Rita Assi, Ali Shamseddine   +4 more
doaj   +1 more source

Therapeutic Plasma Exchange in the Elderly: Rare Indications but Good Tolerability

Journal of Clinical Apheresis, Volume 41, Issue 3, June 2026.
ABSTRACT Therapeutic plasma exchange (TPE) is used for a wide range of indications and is associated with well‐described adverse events. However, no study has specifically focused on tolerance in elderly patients, despite its expected increasing use in this population. We conducted a single‐center retrospective case–control study of all patients aged ≥ 
Valentin Coirier, Quentin Quelven, Pauline Guillot, Elie Jalaber, Floriane L’Her, Vincent Joussellin, Félicie Bélicard, Kieran Pinceaux, Adel Maamar, Mathieu Lesouhaitier, Jean‐Marc Tadié, Nicolas Terzi   +11 more
wiley   +1 more source