Results 81 to 90 of about 43,207 (322)

Risk of Microangiopathy in Patients with Epilepsy under Long-term Antiepileptic Drug Therapy

Frontiers in Neurology, 2018
BackgroundLong-term antiepileptic drug (AED) therapy is considered a risk factor of atherosclerosis. Furthermore, the duration of therapy contributes to acceleration of large-vessel atherosclerosis. Therefore, in this study, we tested the hypothesis that
Nai-Ching Chen, Chih-Hsin Chen, Tsu-Kung Lin, Shang-Der Chen, Shang-Der Chen, Meng-Han Tsai, Chiung-Chih Chang, Wan-Chen Tsai, Yao-Chung Chuang, Yao-Chung Chuang, Yao-Chung Chuang, Yao-Chung Chuang   +11 more
doaj   +1 more source

Telangiectasia in Systemic Sclerosis Is a Marker of Increased Disease Morbidity and Mortality: Analyses From the Australian Scleroderma Cohort Study

Australasian Journal of Dermatology, EarlyView.
ABSTRACT This Australian retrospective cohort analysis of 1977 patients investigates and expands on correlates of telangiectasia in systemic sclerosis to determine whether this cutaneous sign is a potential surrogate marker for disease progression and prognosis.
Vivien Wai Yun Lai, Dylan Hansen, Maryam Tabesh, Jessica Fairley, Laura Ross, Nava Ferdowsi, Gene‐Siew Ngian, Diane Apostolopoulos, Joanne Sahhar, Lauren V. Host, Jennifer Walker, Gabor Major, Susanna Proudman, Wendy Stevens, Mandana Nikpour, Amanda M. Saracino   +15 more
wiley   +1 more source

Diabetic Microangiopathy [PDF]

, 1966
Microangiopathy is the term applied to the abnormal state of the capillaries, arterioles, and venules found in the diabetic patient. It is characterized principally by thickening of the basement membrane of these small vessels.
Bloodworth, J. M. B., Jr.
core   +1 more source

Cellular Senescence: A Bridge Between Diabetes and Microangiopathy [PDF]

Cellular senescence is a state of permanent cell cycle arrest and plays an important role in many vascular lesions. This study found that the cells of diabetic patients have more characteristics of senescence, which may cause microvascular complications.
Buyu Guo, Guomao Zhu, Jiahui Liu, Yaqi Wang, Songbo Fu, Qianqian Liu, Na Wang, Yichen Yang   +7 more
core   +1 more source

Microangiopathy—A Potential Contributing Factor to Idiopathic Polyneuropathy: A Mini Review

Frontiers in Neurology, 2018
Chronic idiopathic axonal polyneuropathy (CIAP) is a slowly progressive predominantly sensory axonal polyneuropathy. The prevalence of CIAP increases with age.
Kristin Samuelsson, Kristin Samuelsson, Rayomand Press, Rayomand Press   +3 more
doaj   +1 more source

A case of “smoldering” immune‐mediated thrombotic thrombocytopenic purpura manifesting as recurrent cardioembolic stroke

Clinical Case Reports, 2021
Prompt recognition and treatment for thrombotic thrombocytopenic purpura (TTP) are critical to prevent the irreversible manifestations of this rare and quickly fatal hematologic disorder.
Mark E. Pepin, Eyad Saca, Soo Y. Kwon, Jori May   +3 more
doaj   +1 more source

Cancer and Thrombotic Microangiopathy [PDF]

Journal of Oncology Practice, 2016
Cancer-Associated Thrombotic Microangiopathy Thrombotic microangiopathy (TMA) is a general term that describes the clinical features of thrombocytopenia and microangiopathic hemolytic anemia, in conjunction with a raised lactate dehydrogenase level, reticulocytosis, and often hyperbilirubinemia.
openaire   +2 more sources

Thrombotic Microangiopathy and the Kidney [PDF]

Clinical Journal of the American Society of Nephrology, 2017
Thrombotic microangiopathy can manifest in a diverse range of diseases and is characterized by thrombocytopenia, microangiopathic hemolytic anemia, and organ injury, including AKI. It can be associated with significant morbidity and mortality, but a systematic approach to investigation and prompt initiation of supportive management and, in some cases ...
Brocklebank V, Wood KM, Kavanagh D
openaire   +3 more sources

Prenatal exome sequencing of fetuses with central nervous system anomalies based on prenatal ultrasound and magnetic resonance imaging diagnosis: A retrospective cohort study with a systematic review and meta‐analysis

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Prenatal exome sequencing significantly improves diagnostic yield over chromosomal microarray analysis for fetal CNS abnormalities, with a diagnostic yield of 16% in our cohort and 27% in the meta‐analysis. Diagnostic yields vary across different phenotypes. Abstract Introduction Fetal central nervous system (CNS) abnormalities have diverse etiologies,
Jia Yao, Yan Wang, Gang Li, Zhitao Zhang, Yuan Lv, Lizhu Chen   +5 more
wiley   +1 more source

Adult‐onset Coats disease: A systematic review and meta‐analysis of imaging biomarkers and targeted therapies

Acta Ophthalmologica, EarlyView.
Abstract Coats disease diagnosed in adulthood is a rare idiopathic retinal telangiectatic vasculopathy that may differ in phenotype from childhood‐diagnosed cases. This systematic review synthesizes current evidence to characterize its clinical spectrum, imaging features, treatment outcomes and underlying mechanisms, with a focus on immunovascular ...
Catarina Francisco, Nisa Silva, Camiel J. F. Boon   +2 more
wiley   +1 more source