Results 81 to 90 of about 39,059 (218)

Timing and duration of glucagon‐like peptide‐1 receptor agonist use and risk of nonarteritic anterior ischaemic optic neuropathy

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To investigate the association between glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) use and nonarteritic anterior ischaemic optic neuropathy (NAION) in type 2 diabetes, examining treatment recency and cumulative duration. Methods This nationwide registry‐based nested case–control study utilizedz Danish health registries (1996 ...
Siar Niazi   +9 more
wiley   +1 more source

Roles of Mitochondrial Dysfunction in Diabetic Kidney Disease: New Perspectives from Mechanism to Therapy

open access: yesBiomolecules
Diabetic kidney disease (DKD) is a common microvascular complication of diabetes and the main cause of end-stage renal disease around the world. Mitochondria are the main organelles responsible for producing energy in cells and are closely involved in ...
Yichen Yang   +6 more
doaj   +1 more source

Cerebroretinal Microangiopathy (Susac Syndrome)

open access: yes, 1999
Retinal signs of Susac\u27s Syndrome in acute phase consist of areas of retinal artery infarction from branch retinal artery occlusions. This fundus shows two area of retinal infarction from occlusion of both superior and inferior branch retinal ...
William F. Hoyt, MD
core  

Red lines and green lights: Gene therapy for inherited erythroid disorders beyond the haemoglobinopathies

open access: yesBritish Journal of Haematology, EarlyView.
Gene therapy is revolutionizing treatment paradigms for haemoglobinopathies, establishing a translational framework for disorders that impact red blood cell development. In their paper, Joshi et al. describe the preclinical and early clinical landscape of gene therapies for non‐haemoglobinopathy erythroid disorders and highlight common thematic ...
Gaurav Joshi   +3 more
wiley   +1 more source

Moschcowitz Disease in pediatric. [PDF]

open access: yesBatna Journal of Medical Sciences
Hemichorea Moskowitz disease is a rare hematological disorder known to be an autoimmune disease in most patients. Most cases of thrombotic thrombopenic purpura (TTP) are caused by problems with an enzyme or protein in the blood called ADAMTS13.
Samira AGGOUNE, Mohamed Faouzi SEDDIKI
doaj   +1 more source

Clinical case of thrombotic microangiopathy in obstetric practice [PDF]

open access: yes, 2017
Trombotic microangiopathy is heterogeneous group of the diseases united by a community of a histological and clinical implications at difference of pathogenetic mechanisms, presents clinical-morphological syndrome characterizing a lesion of vessels of a ...
E. M. Shifman   +5 more
core  

IL-20RA is Associated with the Risk of Diabetic Microangiopathy: A Bidirectional Mendelian Randomization Analysis and Clinical Validation [PDF]

open access: yes
Jinju Li,1 Hao Yang,2 Tingting Wang,1 Nuobing Ruan,1 Yixuan Lin,3 Zhaohui Fang3,4 1The First Clinical Medical College of Anhui University of Traditional Chinese Medicine, Hefei, Anhui, People’s Republic of China; 2Department of Geriatrics, The Second ...
Yang H   +5 more
core  

Diagnosis of de novo localized thrombotic microangiopathy by surveillance biopsy

open access: yes, 2007
Thrombotic microangiopathy has been reported in association with calcineurin inhibitors and less frequently with sirolimus in renal transplant patients. The diagnosis of thrombotic microangiopathy is typically made by diagnostic biopsy in the setting of ...
Lau, Keith K.   +6 more
core   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Thrombotic microangiopathy in allogeneic stem cell transplantation in childhood

open access: yes, 2010
PubMedID: 20716043Objectives: We define the incidence, risk factors, and mortality rates for the occurrence of thrombotic microangiopathy in 50 children who underwent transplants between January 2006 and June 2008 at 2 Turkish pediatric centers ...
Tanyeli A.   +6 more
core   +2 more sources

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