Results 131 to 140 of about 695,874 (306)
Advanced Science, EarlyView.MetaTF is a new computational framework that uses single‐cell RNA sequencing (scRNA‐seq) data to infer transcription factor activity with the aim to help in deciphering cells identity starting from a heterogeneous population, and apply it to characterize mouse hematopoietic stem cells and breast cancer epithelial cells, thus identifying a novel subset ...
Yongfei Hu +15 more
wiley +1 more source
Correlation Statistics for cDNA Microarray Image Analysis [PDF]
arXiv, 2005 In this report, correlation of the pixels comprising a microarray spot is investigated. Subsequently, correlation statistics namely: Pearson correlation and Spearman rank correlation are used to segment the foreground and background intensity of microarray spots.
arxiv
Detection of differentially expressed genes in primary tumor tissues using representational differences analysis coupled to microarray hybridization [PDF]
, 1998 Scott M. Welford +6 more
openalex +1 more source
Nonlinear Dimension Reduction for Microarray Data [PDF]
, 2007 [Biomedical ...
Leblond, Frédéric +3 more
core
Advanced Science, EarlyView.These findings elucidate the innovative role of HIC1 as a transcriptional activator in GC, driving the initiation of pyroptosis and enhancing CD8+ T cell infiltration, which has certain novelty and creative significance. Collectively, targeting HIC1 can present an appealing immunotherapeutic strategy to improve outcomes in GC patients.
Mengjie Kang +4 more
wiley +1 more source
Searching for Evidence of Altered Gene Expression: a Comment on Statistical Analysis of Microarray Data [PDF]
, 1999 Janet Wittes, Haya Friedman
openalex +1 more source
Isolation Techniques of Micro/Nano‐Scaled Species for Biomedical Applications
Advanced Science, EarlyView.Separating micro/nano‐scale bioparticles from samples is essential for disease diagnosis, prevention, and monitoring. Therefore, a comprehensive overview of the latest advanced separation technologies is provided, and characteristics and limitations based on six key performance parameters, including purity, recovery rate, throughput, resolution, size ...
Qing Lu, Zhinan Zhang, Xianting Ding
wiley +1 more source
Analysis of gene expression in lymphoid malignancies using the Lymphochip cDNA microarray [PDF]
, 1999 Louis M. Staudt
openalex +1 more source
Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization
Advanced Science, EarlyView.This study identified a natural compound, isoquercitrin, which significantly alleviated kidney inflammation and fibrosis by inhibiting STAT3 activity. Isoquercitrin forms a strong, noncovalent bond that directly binds to STAT3. Isoquercitrin binds to the pY+1 pocket of the SH2 domain of STAT3 via hydrogen bonding with Ser668, Gln635, and Gln633 ...
Chen Xuan +12 more
wiley +1 more source
Estimating robustness of the tileShuffle method with repeated probes [PDF]
arXiv, 2014 In this paper the TileShuffle method is evaluated as a search method for candidate lncRNAs at 8q24.2. The method is run on three microarrays. Microarrays which all contained the same sample and repeated copies of tiled probes. This allows the coherence of the selection method within and between microarrays to be estimated by Monte Carlo simulations on ...
arxiv