Results 131 to 140 of about 344,370 (242)

Transcriptomic and Neuroimaging Decoding of Brain‐Immune Crosstalk in Thyroid Eye Disease

Advanced Science, EarlyView.
This study employed an imaging transcriptomics framework integrating resting‐state fMRI with Allen Human Brain Atlas transcriptomic data, coupled with peripheral blood RNA sequencing, to decode brain‐immune crosstalk in thyroid eye disease. Frontal, parietal, subcortical, and brainstem regions were identified as key neuroimmune‐ vulnerable regions ...
Haiyang Zhang, Yuting Liu, Shufan Jiang, Zilin Fang, Mengda Jiang, Xiaofeng Tao, Tianyi Zhu, Jipeng Li, Sijie Fang, Xuefei Song, Yinwei Li, Jing Sun, Chuanjun Tong, Zhengrun Gao, Huifang Zhou, Xianqun Fan   +15 more
wiley   +1 more source

Parents' perceived safety, usability, and acceptability of vaccination through microarray patches: A preliminary multi-national cross-sectional survey. [PDF]

Hum Vaccin Immunother
Berger MN, Mathieu E, Davies C, Shaban RZ, Bag S, Skinner SR.   +5 more
europepmc   +1 more source

Deciphering the Impact of RAC1‐SPTAN1 in ARPKD Cystogenesis Using Multifaceted Models

Advanced Science, EarlyView.
Distal/connecting tubules expressing SLC8A1 have been suggested as a potential origin of ARPKD cysts. SPTAN1 has been identified as a key molecule in ARPKD cyst formation. Restoring SPTAN1 in PKHD1−/− organoids reduced cyst formation, normalized calcium levels, and decreased RAC1/c‐FOS expression, highlighting SPTAN1's role in ARPKD and the potential ...
Shohei Kuraoka, Yuhei Higashi, Suguru Saito, Solmaz Pourgonabadi, Honami Honjoh, Sho Ishigaki, Peter C. Harris, Lisa M. Satlin, Michifumi Yamashita, Ryuji Morizane   +9 more
wiley   +1 more source

Diagnostic accuracy and clinical impact of DNA microarray chip in pulmonary mycobacterial infections: a retrospective cohort study. [PDF]

BMC Infect Dis
Xiang B, Zeng W, Wu M, Ye J, Lin Z, Jiang Y.   +5 more
europepmc   +1 more source

Ultrahigh‐Linear Bio‐Inspired Janus Elastomeric Strain Sensor with High Sensitivity and Stretchability via Surface Wrinkle Engineering

Advanced Science, EarlyView.
A bio‐inspired Micro‐wrinkled Janus elastomeric flexible strain sensor mimicking wrinkled‐leaf viburnum is developed. Endowed with a synergistic sensing mechanism including wrinkle‐guided microcracks, modulus‐gradient‐driven strain division, and a parallel conductive circuit, it achieves ultra‐high linearity, sensitivity, wide strain range, and ...
Jing Lin, Ye Li, Simi Yu, Xing Cheng, Longxin Qian, Yufei Chen, Womin Li, Zhipeng Yang, Yinlei Lin, Dechao Hu, Jianyi Luo, Lan Liu   +11 more
wiley   +1 more source

Differentially expressed circular RNA profile in hemorrhagic and ischemic moyamoya disease. [PDF]

Biomed Rep
Zhao M, Li W, Ye X, Zhang Q, Zhang Y, Zhao J.   +5 more
europepmc   +1 more source

A Solution for Exosome‐Based Analysis: Surface‐Enhanced Raman Spectroscopy and Artificial Intelligence

Advanced Intelligent Discovery, EarlyView.
Exosomes are emerging as powerful biomarkers for disease diagnosis and monitoring. This review highlights the integration of surface‐enhanced Raman spectroscopy with artificial intelligence to enhance molecular fingerprinting of exosomes. Machine learning and deep learning techniques improve spectral interpretation, enabling accurate classification of ...
Munevver Akdeniz, Zakarya Al‐Shaebi, Omer Aydin   +2 more
wiley   +1 more source

An exploratory microarray analysis of estrogen-mediated gene expression in central pathways that control energy balance in female rats (Rattus norvegicus). [PDF]

BMC Res Notes
Lang H, Burch K, Sloan D.
europepmc   +1 more source

gnSPADE: Incorporating Gene Network Structures Enhances Reference‐Free Deconvolution in Spatial Transcriptomics

Advanced Intelligent Systems, EarlyView.
gnSPADE integrates gene‐network structures into a probabilistic topic modeling framework to achieve reference‐free cell‐type deconvolution in spatial transcriptomics. By embedding gene connectivity within the generative process, gnSPADE enhances biological interpretability and accuracy across simulated and real datasets, revealing spatial organization ...
Aoqi Xie, Yuehua Cui
wiley   +1 more source

Clinical Insights From a Case of Sifrim‐Hitz‐Weiss Syndrome With a CHD4 Variant: Expanding the Phenotypic Spectrum and Its Response to Growth Hormone Therapy

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT To enhance clinicians' understanding of Sifrim‐Hitz‐Weiss syndrome (SIHIWES), this study investigated the clinical phenotypes, genetic characteristics, and response to growth hormone therapy in a patient. A case of a patient with global developmental delay and distinctive facial features is presented.
Jianmei Zhang, Shuangzhong Chen, Guanping Dong, Suhong Yang, Ping Wang, Qiong Zhou, Pingping Wang   +6 more
wiley   +1 more source