Results 141 to 150 of about 695,874 (306)
Based on IP‐MS analysis, BAG2 is confirmed to be essential for ubiquitination and protein homeostasis regulation of STING in cervical cancer. BAG2 inhibits the ubiquitination and degradation of STING by forming a complex with STUB1, thereby activating the type I IFN signaling pathway and inhibiting the development of cervical cancer.
Shijie Yao+6 more
wiley +1 more source
The cholesteryl ester transfer protein (CETP) raises cholesterol levels in the brain
The cholesteryl ester transfer protein (CETP) is a lipid transfer protein responsible for the exchange of cholesteryl esters and triglycerides between lipoproteins.
Felix Oestereich+9 more
doaj
Toxicogenomics: the application of microarrays to toxicology [PDF]
Peter R. Holden, W.D. Pennie
openalex +1 more source
The study identifies a novel circular RNA derived from the TP53 gene (circTP53), which is upregulated in HNSCC and correlates with poor patient prognosis. It demonstrates that circTP53 promotes HNSCC progression by interacting with USP10, stabilizing both proteins, enhancing deubiquitination of p53, and thereby influencing tumor growth, with its ...
Yin Wang+11 more
wiley +1 more source
A novel JNK2/SREBP-1c pathway involved in insulin-induced fatty acid synthesis in human adipocytes
Insulin plays important roles in apoptosis and lipid droplet (LD) formation, and it is one of the determinants involved in increasing fat mass. However, the mechanisms underlying insulin-induced enlargement of fat mass remain unclear.
Minoru Ito+7 more
doaj
Strawberry on chips: gene expression analysis during strawberry development using cDNA microarrays [PDF]
Asaph Aharoni+5 more
openalex +1 more source
Activation of HTR2B suppresses osteosarcoma progression through the STAT1‐NLRP3 inflammasome pathway and promotes OASL1+ Macrophage production to enhance anti‐tumor immunity. Abstract Osteosarcoma is a primary malignant bone tumor originating from mesenchymal tissue, and associated with poor prognosis.
Zhen Huang+7 more
wiley +1 more source
Microarray analysis of gene expression in a transgenic Caenorhabditis elegans Alzheimer disease model [PDF]
Chris D. Link+4 more
openalex +1 more source