Results 151 to 160 of about 544,008 (293)

The Gene Expression Profile of Human Umbilical Vein Endothelial Cells Stimulated by Tumor Necrosis Factor a Using DNA Microarray Analysis

, 2000
Takeshi Murakami, Chikage Mataki, Chizuru Nagao, Michihisa Umetani, Y Wada, Masami Ishii, Shuichi Tsutsumi, Takahide Kohro, Akio Saiura, Hiroyuki Aburatani, Takao Hamakubo, Tatsuhiko Kodama   +11 more
openalex   +2 more sources

Genome microarray analysis of transcriptional activation in multidrug resistance yeast mutants [PDF]

, 2000
Joseph L. DeRisi, Bart van den Hazel, Philippe Marc, Elisabetta Balzi, Patrick O. Brown, Claude Jacq, André Goffeau   +6 more
openalex   +1 more source

The TET3/GATA6 Axis Drives Lipid Metabolism and Therapeutic Vulnerabilities in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
The DNA demethylase TET3 drives lipid metabolic reprogramming in pancreatic ductal adenocarcinoma via a non‐catalytic mechanism. TET3 recruits histone deacetylases to repress GATA6, sustaining lipogenic enzyme expression and ferroptosis resistance.
Shuai Liu, Shaobo Kang, Na Lin, Wenqi Zhang, Shiwen Wang, Yuqing Ren, Xiaofan Ding, Jianxiu Yu, Ruiyu Xie   +8 more
wiley   +1 more source

Autoantibody profiling using microarray identifies biomarkers associated with chemoimmunotherapy efficacy and immune-related adverse events in lung cancer patients. [PDF]

Clin Exp Med
Wang Z, Yu B, Guo S, Chen Q, Zhang X, Zhang R, Fan Y, Lv J, Dong Y, Niu Q, Zhang X, Liu Y, Chen L, Wu Y, Xu X, Liu R, Jiao Y, Hu D, Jia Y, Wang B, Cao Z, Tan Q, Yu X.   +22 more
europepmc   +1 more source

PIEZO1‐GPX4 Axis Mediates Mechanical Stress‐Induced Vertebral Growth Plate Dysplasia via Ferroptosis Activation

Advanced Science, EarlyView.
Mechanical stress activates PIEZO1 in vertebral growth plate chondrocytes, triggering ferroptosis through direct binding and inhibition of GPX4. This axis promotes lipid peroxidation and pathological ossification, accelerating spinal deformities. Clinical and genetic evidence (Piezo1‐cKO) confirms its role in scoliosis progression.
Fei Chen, Fushuai Peng, Shuqing Chen, Yukun Du, Jianyi Li, Yuanyuan Fan, Zichen Cui, Guanghui Gu, Han Zhang, Zhensong Jiang, Guodong Wang, Xingzhi Jing, Jun Dong, Tao Li, Yongming Xi   +14 more
wiley   +1 more source

Oligonucleotide microarray based detection of repetitive sequence changes

, 2000
Joseph G. Hacia, Keith Edgemon, N. Fang, R Mayer, D. Sudano, Nathaniel G. Hunt, Francis S. Collins   +6 more
openalex   +1 more source

Comprehensive Characterization of the Immune Microenvironment Based on Nested Resampling Machine Learning Framework Identifies TRAF3 Interacting Protein 3 as a Promising Regulator to Improve the Resistance to Immunotherapy in Glioma

Advanced Science, EarlyView.
This study develops a nested resampling machine learning framework to establish the Immune Glioma Survival Signature (IGLoS), which stratifies glioma patients and predicts immunotherapy resistance. Multi‐omics analyses reveal TRAF3IP3 as a pivotal regulator of PD‐L1 expression and T‐cell exhaustion via ERK‐NFATC2 signaling.
Yanbo Yang, Fei Wang, Yulian Zhang, Run Huang, Chuanpeng Zhang, Lu Zhao, Hanhan Dang, Xinyu Tao, Yue Lu, Dengfeng Lu, Yunsheng Zhang, Kun He, Jiancong Weng, Zhouqing Chen, Zhong Wang, Yanbing Yu   +15 more
wiley   +1 more source

A Sister Mary Joseph's nodule in fallopian tube cancer: exploring the metastatic pathway through gene expression profiling-a case report. [PDF]

J Med Case Rep
Uyama T, Matoba Y, Nakahara H, Ishikawa A, Niitsu H, Nakamoto K, Koh I, Mii S, Hinoi T, Banno K.   +9 more
europepmc   +1 more source

EGR1 Target Genes in Prostate Carcinoma Cells Identified by Microarray Analysis [PDF]

, 2000
John Svaren, Torsten Ehrig, Sarki A. Abdulkadir, Markus U. Ehrengruber, Mark A. Watson, Jeffrey Milbrandt   +5 more
openalex   +1 more source

Dual‐Targeted Nanovesicles Induced Cancer Stem‐Like Cell Differentiation to Sensitize Hepatocellular Carcinoma Radiotherapy

Advanced Science, EarlyView.
The existence of Pin1 and Notch1 crosstalk is identified and verified in HCC, and the crucial function of this crosstalk in sustaining the aggressive phenotypes of CSCs and radioresistance. A biomimetic nanovesicle is now developed to block the crosstalk between Pin1 and Notch1 for inducing CSCs differentiation and sensitizing HCC radiotherapy ...
Hongmei Cao, Qian Wang, Yanan Niu, Shuxiang Wang, Haixue Jia, Dianyu Wang, Jinjian Liu, Wei Yuan, Lijun Yang, Jianfeng Liu   +9 more
wiley   +1 more source