Results 251 to 260 of about 544,008 (293)
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2008
High throughput methodologies have increased by several orders of magnitude the amount of experimental microarray data available. Nevertheless, translating these data into useful biological knowledge remains a challenge. There is a risk of perceiving these methodologies as mere factories that produce never-ending quantities of data if a proper ...
Joaquín Dopazo, Fatima Al-Shahrour
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High throughput methodologies have increased by several orders of magnitude the amount of experimental microarray data available. Nevertheless, translating these data into useful biological knowledge remains a challenge. There is a risk of perceiving these methodologies as mere factories that produce never-ending quantities of data if a proper ...
Joaquín Dopazo, Fatima Al-Shahrour
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Microarray challenges in ecology [PDF]
Microarrays are used to measure simultaneously the amount of mRNAs transcribed from many genes. They were originally designed for gene expression profiling in relatively simple biological systems, such as cell lines and model systems under constant laboratory conditions.
Kammenga, J.E.+4 more
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Applied Physiology, Nutrition, and Metabolism, 2008
Adaptations that are the result of exercise require a multitude of changes at the level of gene expression. The mechanisms involved in regulating these changes are many, and can occur at various points in the pathways that affect gene expression. The completion of the human genome sequence, along with the genomes of related species, has provided an ...
Carl Virtanen, Mark Takahashi
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Adaptations that are the result of exercise require a multitude of changes at the level of gene expression. The mechanisms involved in regulating these changes are many, and can occur at various points in the pathways that affect gene expression. The completion of the human genome sequence, along with the genomes of related species, has provided an ...
Carl Virtanen, Mark Takahashi
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2009
Gene expression analysis has progressed rapidly over the past decade from the historical analyses of individual genes to the sophisticated genome surveys routinely performed today. DNA biochips have facilitated this progression and helped accelerate target validation and drug discovery efforts by the pharmaceutical industry.
Ubaldi, Massimo+6 more
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Gene expression analysis has progressed rapidly over the past decade from the historical analyses of individual genes to the sophisticated genome surveys routinely performed today. DNA biochips have facilitated this progression and helped accelerate target validation and drug discovery efforts by the pharmaceutical industry.
Ubaldi, Massimo+6 more
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Current Opinion in Hematology, 2002
Microarrays are fast becoming routine tools for the high-throughput analysis of gene expression in a wide range of biologic systems, including hematology. Although a number of approaches can be taken when implementing microarray-based studies, all are capable of providing important insights into biologic function.
Darren Flower+2 more
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Microarrays are fast becoming routine tools for the high-throughput analysis of gene expression in a wide range of biologic systems, including hematology. Although a number of approaches can be taken when implementing microarray-based studies, all are capable of providing important insights into biologic function.
Darren Flower+2 more
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2007
Gene expression microarrays are being used widely to address a myriad of complex biological questions. To gather meaningful expression data, it is crucial to have a firm understanding of the steps involved in the application of microarrays. The available microarray platforms are discussed along with their advantages and disadvantages.
Norman H. Lee, Alexander I. Saeed
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Gene expression microarrays are being used widely to address a myriad of complex biological questions. To gather meaningful expression data, it is crucial to have a firm understanding of the steps involved in the application of microarrays. The available microarray platforms are discussed along with their advantages and disadvantages.
Norman H. Lee, Alexander I. Saeed
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Photoimmobilization for Microarrays
Biotechnology Progress, 2006A photoimmobilization method has been developed for the preparation of microarray biochips. This photoimmobilization method makes it possible to easily covalently immobilize various types of organic molecules and cells on a chip. In addition, by using hydrophilic polymers as matrixes, it is possible to reduce nonspecific interactions with biological ...
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2007
DNA microarray technology has become a powerful tool in the arsenal of the molecular biologist. Capitalizing on high precision robotics and the wealth of DNA sequences annotated from the genomes of a large number of organisms, the manufacture of microarrays is now possible for the average academic laboratory with the funds and motivation.
David W. Petersen, Ernest S. Kawasaki
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DNA microarray technology has become a powerful tool in the arsenal of the molecular biologist. Capitalizing on high precision robotics and the wealth of DNA sequences annotated from the genomes of a large number of organisms, the manufacture of microarrays is now possible for the average academic laboratory with the funds and motivation.
David W. Petersen, Ernest S. Kawasaki
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Zeitschrift für Rheumatologie, 2011
Since their development in the 1990s DNA microarrays have advanced to one of the most important technologies for biomedical research. Miniaturization enables up to 1 million different sequence-specific DNA hybridization tests to be performed on an area of less than 2 cm². Depending on the selection of oligonucleotide sequences, which are assembled on a
R, Biesen, T, Häupl
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Since their development in the 1990s DNA microarrays have advanced to one of the most important technologies for biomedical research. Miniaturization enables up to 1 million different sequence-specific DNA hybridization tests to be performed on an area of less than 2 cm². Depending on the selection of oligonucleotide sequences, which are assembled on a
R, Biesen, T, Häupl
openaire +2 more sources