Results 261 to 270 of about 695,874 (306)

Synthesis of Versatile DNA‐Conjugated Aldehydes by Controlled Oxidation of Amines

open access: yesAngewandte Chemie International Edition, Accepted Article.
Aldehyde‐functionalized oligonucleotides have found diverse applications in chemical biology and material science. However, due to the electrophilic nature of aldehydes, incorporating aldehyde functionalities directly into DNA is challenging, particularly for highly reactive alkyl aldehydes.
Yizhou Li   +6 more
wiley   +1 more source

Technological Innovations and Applications of Spatial Transcriptomics in Livestock and Poultry Research

open access: yesAnimal Research and One Health, EarlyView.
The paper is divided into three main sections: a review of the development of spatial transcriptomics technology, its applications in livestock and poultry research, and its future prospects. This article provides an overview of the current state of spatial transcriptomics in animal research, exploring its integration with multiomics technologies as ...
Mingyu Wang   +5 more
wiley   +1 more source

<i>MDM2</i> Knockdown Reduces the Oncogenic Activities and Enhances NIS Protein Abundance in Papillary Thyroid Cancer. [PDF]

open access: yesCancer Genomics Proteomics
Shen DH   +9 more
europepmc   +1 more source

Fresh insights into the light‐induced pineal gland circadian rhythm transmission mechanism derived from mRNA and miRNA profiling

open access: yesAnimal Research and One Health, EarlyView.
Mechanisms of light in regulating the chick pineal clock. Abstract The circadian clock significantly impacts animal health and productivity, with light playing a crucial role in regulating circadian rhythms. However, the mechanisms behind light‐induced circadian transmission remain unclear, particularly in light‐sensitive avian species.
Yunlei Li   +10 more
wiley   +1 more source

Injecting new ideas into microarray printing

open access: bronze, 2000
Thomas M. Harris   +2 more
openalex   +1 more source

Genome‐Wide Aggregated Trans Effects Analysis Identifies Genes Encoding Immune Checkpoints as Core Genes for Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective The sparse effector “omnigenic” hypothesis postulates that the polygenic effects of common single nucleotide polymorphisms (SNPs) on a typical complex trait are mediated by trans effects that coalesce on expression of a relatively sparse set of core genes.
Athina Spiliopoulou   +9 more
wiley   +1 more source

Oligonucleotide microarray based detection of repetitive sequence changes

open access: gold, 2000
Joseph G. Hacia   +6 more
openalex   +1 more source

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