Results 281 to 290 of about 907,938 (379)

The Utility of the DNA Microarray Scanner to Simplify the Immunofluorescence Evaluation of Autoimmune Bullous Diseases

open access: green, 2009
Satori Iwamoto   +7 more
openalex   +1 more source

scPER: A Rigorous Computational Approach to Determine Cellular Subtypes in Tumors Aligned With Cancer Phenotypes From Total RNA Sequencing

open access: yesAdvanced Science, EarlyView.
scPER presents an adversarial‐autoencoder framework that deconvolves bulk total RNA‐seq to quantify tumor‐microenvironment cell types and uncover phenotype‐linked subclusters. Across diverse benchmarks, scPER improves accuracy over existing tools.
Bingrui Li, Xiaobo Zhou, Raghu Kalluri
wiley   +1 more source

DOT1L inhibition exerts the anti-tumor effect by activating interferon signaling in breast cancer cells. [PDF]

open access: yesClin Epigenetics
Yoshido A   +16 more
europepmc   +1 more source

Forsythoside E Alleviates Liver Injury by Targeting PKM2 Tetramerization to Promote Macrophage M2 Polarization

open access: yesAdvanced Science, EarlyView.
Here, the study shows for the first time that Forsythoside E (FE) can promote PKM2 tetramerization by binding to its K311 site. Furthermore, it induces metabolic reprogramming of macrophages and inhibits NLRP3 expression. Finally, it can alleviate sepsis‐induced liver injury by promoting M2 anti‐inflammatory polarization.
Bingxin Wu   +8 more
wiley   +1 more source

Chromosomal microarray versus karyotyping for prenatal diagnosis.

open access: yesNew England Journal of Medicine, 2012
R. Wapner   +23 more
semanticscholar   +1 more source

Spatial Transcriptomics and snRNA‐seq Expose CAF Niches Orchestrating Dual Stromal‐Immune Barriers in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
HmmyCAFs may form a triple immunosuppressive niche: possibly secrete ECM (POSTN, etc.) as physical barriers to block CD8⁺ T cells, induce CD8⁺ T exhaustion via those molecules, and use HIF‐1α‐driven metabolism to create acidic, nutrient‐poor microenvironments that suppress T cells.
Yingxue Li   +12 more
wiley   +1 more source

Comparative Study on Swarm Intelligence Techniques for Biclustering of Microarray Gene Expression Data

open access: green, 2013
R. Balamurugan   +6 more
openalex   +1 more source

Microarray data analysis: from disarray to consolidation and consensus

open access: yesNature reviews genetics, 2006
D. Allison   +3 more
semanticscholar   +1 more source

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