Results 281 to 290 of about 902,749 (382)

Navigating the microarray landscape: a comprehensive review of feature selection techniques and their applications. [PDF]

Front Big Data
Wang F, Zain AM, Ren Y, Bahari M, Samah AA, Ali Shah ZB, Yusup NB, Jalil RA, Mohamad A, Azmi NFM.   +9 more
europepmc   +1 more source

Synergistic Promotion of Triple‐Negative Breast Cancer Tumorigenesis and Metastasis by Oral Polystyrene Nanoplastics Exposure via Alloprevotella‐Derived Glutamate and Platelet Activation

Advanced Science, EarlyView.
Polystyrene nanoplastics (PS‐NPs) administered via oral exposure accelerate triple‐negative breast cancer (TNBC) progression by synergistically modulating gut microbiota‐derived glutamate production and platelet activation. This study uncovers a pivotal crosstalk between microbial metabolites and platelet‐tumor interactions, offering mechanistic ...
Leilei Zhu, Peihao Xu, Mingyuan Zhou, Kewei Li, Shasha Tian, Xuemei Fan, Junling Liu, Baodong Ye, Zhishan Ding, Yingzhi Shen   +9 more
wiley   +1 more source

LIMK1 is a prognosis and treatment biomarker in hepatocellular carcinoma. [PDF]

Sci Rep
Jiang NF, Zhou Z, Zhang HP.
europepmc   +1 more source

Smohaze‐Upregulated RFWD3 Competes with TRIM24 to Stabilize TREX1 and Reduce Cytosolic dsDNA in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
The E3 ubiquitin ligase RFWD3 binds the exonuclease TREX1 and protects it from TRIM24‐mediated ubiquitination and degradation, leading to the eradication of intracellular dsDNA, inhibition of the cGAS‐STING pathway, and immunosuppressive microenvironment of lung cancer.
Xue‐Yan Shi, Yu‐Ke Shen, Meng‐Yao Lv, Yu Sun, Yong‐Fang Lin, Zheng Wang, Xiao‐Liang Jie, Zheng Liu, Yang‐Tong Liu, Yang‐Xin Fu, Zhenhua Ren, Gui‐Zhen Wang, Guang‐Biao Zhou   +12 more
wiley   +1 more source

High-throughput screening of monoclonal antibodies against carbapenemases using a multiplex protein microarray platform. [PDF]

Front Microbiol
Braun SD, Reinicke M, Diezel C, Müller E, Frankenfeld K, Schumacher T, Arends H, Monecke S, Ehricht R.   +8 more
europepmc   +1 more source

Autologous Organoid‐T Cell Co‐Culture Platform for Modeling of Immune‐Mediated Drug‐Induced Liver Injury

Advanced Science, EarlyView.
A matrix‐free human liver organoid–T cell co‐culture platform enables modeling of immune‐mediated drug‐induced liver injury (iDILI). Using flucloxacillin and patient‐matched cells, this system recapitulates HLA‐B*57:01–restricted CD8⁺ T cell activation and hepatocyte damage.
Fadoua El Abdellaoui Soussi, Michael Brusilovsky, Emma Buck, W Clark Bacon, Sina Dadgar, Aaron Fullerton, Victoria Marsh Durban, Riccardo Barrile, Michael A. Helmrath, Takanori Takebe, Adrian Roth, Magdalena Kasendra   +11 more
wiley   +1 more source

Discovering CRIP1: a novel core gene in osteoarthritis pathogenesis. [PDF]

Hereditas
Chen Q, Luo M, Kuang W, Guo X, Wu H, Wu S, Liu S, Wen Y, Zhou C, He M.   +9 more
europepmc   +1 more source

Chromosomal microarray versus karyotyping for prenatal diagnosis.

New England Journal of Medicine, 2012
R. Wapner, C. Martin, B. Levy, B. Ballif, C. Eng, J. Zachary, Melissa Savage, L. Platt, D. Saltzman, W. Grobman, S. Klugman, T. Scholl, J. Simpson, K. McCall, V. Aggarwal, B. Bunke, O. Nahum, Ankita Patel, A. Lamb, E. Thom, A. Beaudet, D. Ledbetter, L. Shaffer, L. Jackson   +23 more
semanticscholar   +1 more source

Clathrin Light Chain B Drives Hepatocellular Carcinoma Progression Through Dual Mechanisms: Small Extracellular Vesicle‐Mediated Angiogenesis and the NF‐κB–PCLAF Signaling Axis

Advanced Science, EarlyView.
Clathrin Light Chain B (CLTB) drives hepatocellular carcinoma progression through dual pathways: intracellularly, it activates the NF‐κB–PCLAF axis to enhance small extracellular vesicle (sEV) uptake and tumor proliferation; extracellularly, CLTB‐enriched sEVs bind SH3KBP1 to inhibit its degradation, inducing angiogenesis and vascular leakage ...
Xiaoke Sun, Junchen Guo, Ning Zhao, Guanghua Cui, Yun Bai, Meijuan Ding, Yi Xu, Yu Yang   +7 more
wiley   +1 more source

Transformative insights from transcriptome analysis of colorectal cancer patient tissues: identification of four key prognostic genes. [PDF]

PeerJ
Belder N, Charyyeva S, Abaci Oruc EE, Kawalya H, Sahar NE, Omidvar N, Savas B, Ensari A, Ozdag H.   +8 more
europepmc   +1 more source