Results 241 to 250 of about 185,542 (303)

miR-361-5p contributes to the pathogenesis of Alzheimer's disease. [PDF]

Sci Rep
Jalaiei A, Gharesouran J, Arsang-Jang S, Talebi M, Rezazadeh M, Ghafouri-Fard S.   +5 more
europepmc   +1 more source

AgileMultiIdeogram: Rapid Identification and Visualization of Autozygous Regions Using Illumina Short-Read Sequencing Data. [PDF]

Biology (Basel)
Watson CM, Lascelles C, Raynor M, Elpidorou M, Hany U, Crinnion L, Johnson CA, Sheridan E, Markham AF, Poulter JA, Bonthron DT, Carr IM.   +11 more
europepmc   +1 more source

Fetal and Perinatal Brain MRI Findings in Adaptor Protein Complex 4–Associated Hereditary Spastic Paraplegia

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Purpose Adaptor protein complex 4–associated hereditary spastic paraplegia (AP‐4‐HSP) is a rare childhood‐onset neurogenetic disorder. With gene replacement therapies advancing, early—potentially prenatal—diagnosis holds significant clinical promise.
Alexandra K. Brooks, Vicente Quiroz, Luca Schierbaum, Julian E. Alecu, Katerina Bernardi, Nicole Battaglia, Amy Tam, Joshua Rong, Gregor Kasprian, Edward Yang, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

Transcriptomic Profiling of Gastric Cancer Reveals Key Biomarkers and Pathways via Bioinformatic Analysis. [PDF]

Genes (Basel)
Balikci Cicek I, Kucukakcali Z.
europepmc   +1 more source

Rodent monocyte‐derived macrophages do not express CD163: Comparative analysis using macrophages from living boreoeutherians

Developmental Dynamics, EarlyView.
Abstract Background CD163 is a scavenger receptor predominantly expressed on the surfaces of macrophages in various mammalian species and is a marker of anti‐inflammatory (M2‐like) macrophages. High density of CD163‐positive tumor‐associated macrophages (TAMs) is associated with worse prognosis in various patient tumors.
Yoichi Saito, Yukio Fujiwara, Yasuka L. Yamaguchi, Satomi S. Tanaka, Kyoko Miura, Yoshiyuki Hizukuri, Kyoko Yamashiro, Yasuhiro Hayashi, Yuta Nakashima, Yoshihiro Komohara   +9 more
wiley   +1 more source

Investigating the mechanism of gastrodin-regulated miR-128-3p in methamphetamine dependence via integrated pharmacology. [PDF]

Medicine (Baltimore)
Li H, He Y, Wu Y, Luo C, Peng Y, Liu W, Li J, Huang Y, Chen R, Ma D, Mo Z.   +10 more
europepmc   +1 more source

The transcriptional profile of iron deficiency in patients with heart failure: Heme‐sparing and reduced immune processes

European Journal of Heart Failure, EarlyView.
The analysis workflow, findings and potential clinical consequences of iron deficiency in heart failure (HF). From 881 patients with worsening HF, whole blood transcriptome was analysed using the Affymetrix Human Transcriptome Array (HTA) 2.0. Subjects were stratified according to their transferrin saturation (TSAT) levels as iron‐deficient (TSAT <20%)
Niels Grote Beverborg, Ridha I.S. Alnuwaysir, George Markousis‐Mavrogenis, Martijn F. Hoes, Haye H. van der Wal, Simon P.R. Romaine, Mintu Nath, Andrea Koekoemoer, John G.F. Cleland, Chim C. Lang, Stefan D. Anker, Kenneth Dickstein, Marco Metra, Leong L. Ng, Dirk J. van Veldhuisen, Adriaan A. Voors, Nilesh J. Samani, Peter van der Meer   +17 more
wiley   +1 more source

Molecular mechanisms after optic nerve injury: Neurorepair strategies from a transcriptomic perspective. [PDF]

Neural Regen Res
Chen X, Wei M, Li G.
europepmc   +1 more source

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

Distinct chromosome abnormality patterns for differential diagnosis of hepatocellular carcinoma and cholangiocarcinoma. [PDF]

PLoS One
Ngamsangiam W, Techa-Ay S, Sa-Ngiamwibool P, Watcharadetwittaya S, Deenonpoe R, Techasen A, Sridakhun N, Padthaisong S, Thanee M.   +8 more
europepmc   +1 more source