Results 221 to 230 of about 187,728 (325)

Unraveling the spatial landscape of dystrophinopathies: a transcriptomic approach to Becker and Duchenne muscular dystrophies

The Journal of Pathology, EarlyView.
Abstract Dystrophinopathies are caused by pathogenic variants in the DMD gene, resulting in partial (Becker) or complete loss (Duchenne) of dystrophin. Becker (BMD) and Duchenne muscular dystrophy (DMD) are characterized by progressive muscle wasting, fatty replacement, fibrosis, and loss of function.
Laura GM Heezen, Qirong Mao, Stefan Nicolau, Claudio Novella Rausell, Julia van der Weerd, Jan Kueckelhaus, Rasya Gokul Nath, Jordi Diaz‐Manera, Hermien E Kan, Erik H Niks, Maaike van Putten, Annemieke Aartsma‐Rus, Kevin M Flanigan, Ahmed Mahfouz, Pietro Spitali   +14 more
wiley   +1 more source

Detection of structural DNA variants in medulloblastomas using optical genome mapping. [PDF]

Acta Neuropathol Commun
Kubon N, Bălan M, Koppstein D, Praeger S, Wolter M, Ebert P, Pauck D, Felsberg J, Beez T, Picard D, Remke M, Reifenberger G.   +11 more
europepmc   +1 more source

Stress‐guided photo‐programming of cholesteric liquid crystal elastomers for 2D‐to‐3D shape–color information encoding

Responsive Materials, EarlyView.
We reported a stress‐guided photo‐programming strategy that enables cholesteric liquid crystal elastomers (CLCEs) to achieve synchronous 3D shape morphing and structural color evolution from a single 2D film. Abstract Flexible materials with dynamic structural colors have attracted considerable interest for multilevel information interaction, showing ...
Huimin Wu, Chenyi Bu, Yirui Sun, Rui Guo, Sixing Xiong, Kai Wang, Xiaoxuan Wang, Xiang Fang, Jin Qian   +8 more
wiley   +1 more source

Detection of Microbial Contaminants in Water: Conventional Methods, Pragmatic Alternatives, and Nanosensing Techniques. [PDF]

Microbiologyopen
Adeeyo AO, Edokpayi JN, Alabi MA, Oyetade JA, Ubomba-Jaswa E, Jaca P, Makungo R.   +6 more
europepmc   +1 more source

Sampling, Mobility, and Anchoring in Small‐Body Sampling Robots: A Comprehensive Review

SmartBot, EarlyView.
Small‐body sampling robots are exploration systems that perform contact, sampling, and stable operations on microgravity bodies such as asteroids and comets. The authors review representative robot architectures and key technologies, focusing on the mechanisms, evolution, and coupling of sampling, mobility, and anchoring.
Yurui Shen, Yixin Zhu, Mingxia Bao, Ting Zhang, Jun Wu, Jingbin Hao, Dezheng Hua, Xinhua Liu   +7 more
wiley   +1 more source

Semisupervised approach for dominant gene selection and classification. [PDF]

BMC Bioinformatics
Rastogi R, Bhattarai Lamsal M.
europepmc   +1 more source

Ultrasensitive MicroRNA Detection Combining Reduced Graphene Oxide Electrolyte‐Gated Transistors and Machine Learning

Small, EarlyView.
We developed an ultrasensitive and highly selective biosensor by integrating bio‐functionalized reduced graphene oxide (rGO) electrolyte‐gated transistors (EGTs) and machine learning (ML) to detect miRNAs (miR‐34a, miR‐34b, and miR‐34c) associated with cancer and neurological disorders.
Ana Vitória Ferreira Deleigo, Gabrielle Coelho Lelis, Maria Luisa Braunger, Stefano Casalini, Yasmin Watanabe, Gabriel Ravanhani Schleder, Wilson Tiago Fonseca, Rafael Furlan de Oliveira   +7 more
wiley   +1 more source

FUNCellA: A Tool for Single-Sample Enrichment Analysis and Relative Pathway Activity Estimation in Single-Cell RNA Sequencing Data. [PDF]

Comput Struct Biotechnol J
Zyla J, Mrukwa A, Bilska AG, Szumala K, Polanska J, Marczyk M.   +5 more
europepmc   +1 more source

Evaluating Thiram‐Induced Embryotoxicity Using Integrated In Silico, In Vitro, and Transcriptomic Approaches

Environmental Toxicology, EarlyView.
ABSTRACT Long‐term exposure to low‐dose food contact materials (FCMs) has raised concerns regarding developmental toxicity. In the present study, we prioritized FCMs with potential developmental toxicity using a weight‐of‐evidence computational model, which predicted 127 chemicals to be of high concern.
Chia‐Chi Ho, Chun‐Wei Tung, B. Linju Yen, Chen‐Yi Weng, Ju‐Hsin Hsu, Ming‐Hsien Tsai, Salim Arrokhman, Pinpin Lin   +7 more
wiley   +1 more source

Evaluation of the efficacy of optical genome mapping in prenatal diagnosis: a retrospective cohort study. [PDF]

J Transl Med
Yin K, Lü Y, Zhang H, Li M, Chang J, Yang X, Qi Q, Zhou X, Guo J, Wang Y, Wang C, Li W, Hao N, Jiang Y.   +13 more
europepmc   +1 more source