Results 201 to 210 of about 91,462 (268)

Anatomical–Motor Level Discrepancy in Prenatal Diagnosis of Open Spinal Dysraphism: A 12‐Year Retrospective Observational Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objectives To quantify the discrepancy between anatomical and motor levels in foetuses with open spinal dysraphism and identify prenatal factors associated with this difference. We also examined associations between anatomical level and ultrasound findings. Design Retrospective observational study.
Silvia Arévalo, Elena Moreno, Mar Meléndez, Carlos Giné, Carlota Rodó, Alba Casellas, Alba Farràs, Manel Mendoza, Nerea Maiz   +8 more
wiley   +1 more source

Identification of Potential Biomarkers in Prostate Cancer Microarray Gene Expression Leveraging Explainable Machine Learning Classifiers. [PDF]

Cancers (Basel)
Marouf AA, Rokne JG, Alhajj R.
europepmc   +1 more source

Gonadal Development–Related Genes and a Male‐Specific Genetic Marker Identified in the Endangered Sichuan Taimen (Hucho bleekeri)

Integrative Zoology, EarlyView.
Integrated transcriptomic and proteomic analyses were used to validate gonadal development–related genes and to identify a sex‐specific molecular marker in Hucho bleekeri. ABSTRACT Sex determination and differentiation represent fundamental topics in reproductive biology. Sichuan taimen (Hucho bleekeri), a first‐class national protected fish species in
Qinyao Wei, Hua Li, Yeyu Chen, Huanchao Yang, Jun Du, Zhaobin Song   +5 more
wiley   +1 more source

SPR Sensing: From Biomolecular Interactions to Cell-Based Analysis. [PDF]

Biosensors (Basel)
Genova-Kalou P, Hikova EO, Kereziev T, Kolev PT, Mankov V, Kisov H, Atanasova A, Dyankov GL.   +7 more
europepmc   +1 more source

Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema

Allergy, EarlyView.
This study performed an unbiased molecular profiling of CHE patients across diverse etiologies to identify shared pathogenic drivers and evaluate the impact of IL‐4Rα blockade via dupilumab over 16 weeks. CHE shows a mixed immune signature involving type 1, 2, and 3 pathways with features of atopic dermatitis and psoriasis.
Perrine Gery, Rüçhan Ekren, Emilie Bérard, Aurélie Du‐Thanh, Hugo Rimet, Fatma Jendoubi, Vanina Lenief, Nadia Raison‐Peyron, Amel Bouznad, Maria P. Konstantinou, Jonathan Rioual, Lilian Basso, Juliette Mouiren, Manon Boussier, Brigitte Milpied, Cristina Bulai Livideanu, Louise Jaulent, Florence Hacard, Marine A. Lefevre, Audrey Nosbaum, Julien Seneschal, Marc Vocanson, Carle Paul, Nicolas Gaudenzio, Marie Tauber, on behalf of the French Atopic Dermatitis Network from de GREAT Research group   +25 more
wiley   +1 more source

Integrative cross-platform transcriptomic analysis coupled with machine learning identifies candidate biomarkers of abiotic stress resilience in Arabidopsis thaliana. [PDF]

BMC Plant Biol
Mehdizadeh Hakkak M, Tohidfar M.
europepmc   +1 more source

Detection for New Biomarkers of Tuberculosis Infection Activity Using Machine Learning Methods. [PDF]

Diseases
Starshinova AA, Sabirova A, Koroteeva O, Kudryavtsev I, Rubinstein A, Aquino A, Trulioff AS, Belyaeva E, Kulpina A, Sharipov RA, Tukfatullin RK, Nikolenko NY, Mikhalev A, Savchenko AA, Borisov A, Kudlay D.   +15 more
europepmc   +1 more source

Resolving Endoplasmic Reticulum‐Protein Misfolding Restores Corticosteroid Sensitivity in Experimental Models of Severe Asthma

Allergy, EarlyView.
This study investigates the role of ER stress in steroid resistance in severe asthma. Results from advanced 3D models of human bronchial epithelial cells, steroid‐resistant severe asthma mouse models, and human severe asthma sputum samples show that treatment with ICS in combination with the ER stress inhibitor 4‐PBA significantly enhances steroid ...
Prabuddha S. Pathinayake, Alexandra C. Brown, Nikhil T. Awatade, Philip M. Hansbro, Katherine J. Baines, Richard Y. Kim, Nathan W. Bartlett, Jay C. Horvat, Peter A. B. Wark   +8 more
wiley   +1 more source

Synthesis of highly complex phosphorothioate-modified oligonucleotides on microarrays. [PDF]

Sci Rep
Ilić I, Schaudy E, Lietard J.
europepmc   +1 more source

A proof of concept study on the diagnostic utility of in vivo expressed mycobacterial transcripts in tuberculous pleuritis. [PDF]

Sci Rep
Kaur P, Sharma S, Abhishek S, Aggarwal AN, Kaur K, Yadav R, Sethi S, Bal A, Verma I.   +8 more
europepmc   +1 more source