Results 211 to 220 of about 27,010,024 (292)

Microbiota as the candidate biomarker in pediatric obstructive sleep apnea

open access: yesSleep Research, EarlyView.
Abstract Pediatric obstructive sleep apnea (OSA) is a form of sleep‐disordered breathing in children. Recent studies have focused on characterizing microbiota alterations associated with pediatric OSA and identifying microbial features that may have potential value as future biomarkers. The most commonly used approach for microbiota profiling is second‐
Xiaoyan Li   +4 more
wiley   +1 more source

Ultrasensitive MicroRNA Detection Combining Reduced Graphene Oxide Electrolyte‐Gated Transistors and Machine Learning

open access: yesSmall, EarlyView.
We developed an ultrasensitive and highly selective biosensor by integrating bio‐functionalized reduced graphene oxide (rGO) electrolyte‐gated transistors (EGTs) and machine learning (ML) to detect miRNAs (miR‐34a, miR‐34b, and miR‐34c) associated with cancer and neurological disorders.
Ana Vitória Ferreira Deleigo   +7 more
wiley   +1 more source

Molecular analysis of individuals with suspected 46,XY differences of sex development in a homogenous and understudied population. [PDF]

open access: yesHum Mol Genet
Idris FP   +10 more
europepmc   +1 more source

Enhanced through‐bond energy transfer‐based bioorthogonal probe enables catalytic‐amplified and sensitive detection of microRNA‐21 for clinical lung cancer diagnosis

open access: yesSmart Molecules, EarlyView.
Inverse Diels‐Alder Cycloaddition Reaction was developed for ultrasensitive miR‐21 detection. Based on the enhanced Through‐Bond Energy Transfer and catalytic amplification, it shows a detection limit of 3.58 × 10−18 M and 100 aM–100 nM linear range. It enables high‐contrast cell/tissue imaging and distinguishes lung cancer patients in serum, promising
Yikun Li   +10 more
wiley   +1 more source

Gold‐Modified Mesoporous Carbon Enables Serum Metabolic Fingerprinting for Papillary Thyroid Carcinoma Diagnosis

open access: yesSmall Methods, EarlyView.
A novel MCHS‑Au‑LA substrate is developed for carbon‑gold nanostructure‐initiator mass spectrometry (C‑Au‑NIMS), which acquires metabolic fingerprints of serum samples from papillary thyroid carcinoma (PTC), benign thyroid nodules (BTN), and healthy controls (HC).
Wanwan Yi   +8 more
wiley   +1 more source

Evaluating Thiram‐Induced Embryotoxicity Using Integrated In Silico, In Vitro, and Transcriptomic Approaches

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Long‐term exposure to low‐dose food contact materials (FCMs) has raised concerns regarding developmental toxicity. In the present study, we prioritized FCMs with potential developmental toxicity using a weight‐of‐evidence computational model, which predicted 127 chemicals to be of high concern.
Chia‐Chi Ho   +7 more
wiley   +1 more source

Advances in Diagnostic Technologies of Major Avian Respiratory Viruses: A Review. [PDF]

open access: yesVet Sci
Hu Z   +8 more
europepmc   +1 more source

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