Results 191 to 200 of about 91,659 (259)

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Development and Analytical Evaluation of a Microarray Assay for Quantitative Determination of Human Blood IgG Reactive to Food Antigens in the Italian Population. [PDF]

Food Technol Biotechnol
Mantovani V, Capitani F, Maccari F, Galeotti F, Volpi N.   +4 more
europepmc   +1 more source

The CRABP2–MDK Signaling Axis Promotes Lung Adenocarcinoma (LUAD) Progression and Highlights Prognostic Biomarkers

Molecular Carcinogenesis, EarlyView.
ABSTRACT Lung cancer is the leading cause of cancer‐related mortality worldwide, with LUAD being characterized by high incidence and mortality rates. Despite the use of various treatments, including surgery, chemotherapy, immunotherapy, and molecular targeted therapy, the prognosis in LUAD patients remains unfavorable.
Jingshun Zhang, Cui Zhang, Guopeng Jiang, Xia Liu, Yifan Li, Fuman Wang, Xuefei Sun, Peidao Sun   +7 more
wiley   +1 more source

Detection for New Biomarkers of Tuberculosis Infection Activity Using Machine Learning Methods. [PDF]

Diseases
Starshinova AA, Sabirova A, Koroteeva O, Kudryavtsev I, Rubinstein A, Aquino A, Trulioff AS, Belyaeva E, Kulpina A, Sharipov RA, Tukfatullin RK, Nikolenko NY, Mikhalev A, Savchenko AA, Borisov A, Kudlay D.   +15 more
europepmc   +1 more source

DNA Microarrays and Related Genomics Techniques: Design, Analysis, and Interpretation of Experiments

Journal of the Royal Statistical Society Series A: Statistics in Society, 2007
openaire   +1 more source

Multiomics Insights Into AL Amyloidosis

Medicine Bulletin, EarlyView.
ABSTRACT Light chain amyloidosis is a systemic or localized protein conformational disorder triggered by misfolded immunoglobulin light chains, leading to amyloid fibril deposition. The disease is characterized by multiorgan involvement and delayed diagnosis, contributing to poor prognosis and high mortality rates.
Zixuan Zhang, Ziru Huang, Haoxiang Tang, Xianrun Pan, Rong Wang, Dingding Zhang, Jian Huang   +6 more
wiley   +1 more source

Integrative cross-platform transcriptomic analysis coupled with machine learning identifies candidate biomarkers of abiotic stress resilience in Arabidopsis thaliana. [PDF]

BMC Plant Biol
Mehdizadeh Hakkak M, Tohidfar M.
europepmc   +1 more source

KMT5C‐Mediated H4K20me3 Recruits EWSR1 to Propel Clear Cell Renal Cell Carcinoma Progression via Regulating ACADM Transcription and m6A Modification

Med Research, EarlyView.
A schematic diagram illustrating the KMT5C‐H4K20me3‐EWSR1‐ACADM signaling axis and its role in ccRCC progression. Key Outcomes: KMT5C/H4K20me3 are upregulated in ccRCC and predict poor prognosis. EWSR1 is a novel noncanonical H4K20me3 reader in ccRCC. KMT5C/EWSR1 co‐repress ACADM via transcription and m6A modification. A‐196 + sunitinib synergistically
Chengjian Ji, Da Zhong, Tian Rao, Xiaojun Li, Weiyu Kong, Xi Zhang, Xiyi Wei, Bing Yao, Xinqiang Li, Ninghong Song, Chao Qin   +10 more
wiley   +1 more source

TCOF1 affects Golgi secretory pathway contributing to the angiogenesis in renal cancer. [PDF]

Cell Commun Signal
Grzanka M, Popławski P, Wiśniewski JR, Iwanicka-Nowicka R, Kossowska H, Koblowska M, Rybicka B, Białas A, Piekiełko-Witkowska A.   +8 more
europepmc   +1 more source

SkinDB: A Curated Resource for Dermatological Data Warehousing and Bioinformatics Exploration

Med Research, EarlyView.
SkinDB is an open‐access transcriptomic database integrating 220 datasets and 11,283 samples across six major skin diseases. Its code‐free interface supports cross‐disease analyses, visualizations, and data downloads for dermatological research. ABSTRACT Dermatology lacks a centralized analysis‐ready transcriptomic resource, leaving publicly available ...
Haoxue Zhang, Xiangnan Zhou, Hao Chi, Youping Deng, Lauren Higa, Isam Mohd Ibrahim, Xiaoyong Liu, Yuyao Liu, Jingyuan Ning   +8 more
wiley   +1 more source