Results 151 to 160 of about 568,857 (297)

GALNT10 Affects O‐Glycosylation of IGFBP7 to Promote Tumor Vascular Remodeling and Metastasis of Ovarian Cancer

Advanced Science, EarlyView.
The glycosyltransferase GALNT10 facilitates ovarian cancer metastasis through the induction of tumor cell EMT and tumor vascular dysfunction. GALNT10 enhanced the extracellular secretion of IGFBP7 through O‐GalNAc glycosylation modification at the T188 site, which subsequently interacts with CD93 on endothelial cells, leading to vascular remodeling ...
Yanan Zhang, Ayala Zuha, Zhangxin Wu, Aiping Luo, Bixia Jin, Qinkun Sun, Yuan Li, Qiyu Liu, Hongyan Guo, Chunliang Shang   +9 more
wiley   +1 more source

Identifying Key Biomarkers in Celiac Disease through Analysis of Microarray Data. [PDF]

J Med Signals Sens
Vafadar A, Alashti SK, Alavimanesh S, Savardashtaki A.   +3 more
europepmc   +1 more source

Repurposing Normal Chromosomal Microarray Data to Harbor Genetic Insights into Congenital Heart Disease. [PDF]

Biology (Basel), 2023
Walton NA, Nguyen HH, Procknow SS, Johnson D, Anzelmi A, Jay PY.   +5 more
europepmc   +1 more source

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

Advanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi, Yue Qi Ong, Prativa Majee, Esther SM Wong, Amhed Missael Vargas Velazquez, Kerem Fidan, Pierce Kah‐Hoe Chow, Wai Leong Tam, Ker Kan Tan, Iain Beehuat Tan, Vinay Tergaonkar   +10 more
wiley   +1 more source

Unveiling complex patterns: An information-theoretic approach to high-order behaviors in microarray data. [PDF]

PLoS One
Lacalamita A, Monaco A, Serino G, Marinazzo D, Amoroso N, Bellantuono L, La Rocca M, Maggipinto T, Pantaleo E, Piccinno E, Scalavino V, Tangaro S, Giannelli G, Stramaglia S, Bellotti R.   +14 more
europepmc   +1 more source

Exploring the pathogenesis of osteomyelitis accompanied by diabetic foot ulcers using microarray data analysis. [PDF]

Medicine (Baltimore), 2023
Fan P, Ye H, Zhu C, Xie H.
europepmc   +1 more source

Integrated Microfluidic Platform for High‐Throughput Generation of Intestinal Organoids in Hydrogel Droplets

Advanced Science, EarlyView.
ABSTRACT Organoid research offers valuable insights into human biology and disease, but reproducibility and scalability remain significant challenges, particularly for epithelial organoids. Here, we present an integrated microfluidic platform that addresses these limitations by enabling high‐throughput generation of uniform hydrogel microparticles ...
Barbora Lavickova, Hannah Kronabitter, Mar Cervera‐Negueruela, Eylul Ceylan, Laura Benito‐Zarza, Rubén López‐Sandoval, Irineja Cubela, J. Gray Camp, Jose L. Garcia‐Cordero   +8 more
wiley   +1 more source

A Hybrid Ensemble Equilibrium Optimizer Gene Selection Algorithm for Microarray Data. [PDF]

Biomimetics (Basel)
Su P, Zhao Y, Li X, Ma Z, Wang H.
europepmc   +1 more source

Exploration of the radiosensitivity-related prognostic risk signature in patients with glioma: evidence from microarray data. [PDF]

J Transl Med, 2023
Zhang X, Ren Q, Li Z, Xia X, Zhang W, Qin Y, Wu D, Ren C.   +7 more
europepmc   +1 more source

GOT1 Inhibition Induces Extracellular Matrix Remodeling in Pancreatic Cancer

Advanced Science, EarlyView.
Using tumor tissue engineering, we recreated pancreatic cancer and found that inhibiting glutamic‐oxaloacetic transaminase 1 (GOT1) induces extracellular matrix remodeling and secretome rewiring, as well as promotes cell death. ABSTRACT Pancreatic cancer cells rely on glutamine to sustain their survival in the stiff and poorly vascularized tumor ...
Rodrigo Curvello, Sandra Hauser, Michael Seifert, Christopher K. Barlow, Joel R. Steele, Emma Salisbury, Daniel Croagh, Kathryn S. Stok, Anna V. Taubenberger, Ralf B. Schittenhelm, Daniela Loessner   +10 more
wiley   +1 more source