Results 171 to 180 of about 568,857 (297)

Drug Discovery in Canine Pyometra Disease Identified by Text Mining and Microarray Data Analysis. [PDF]

Biomed Res Int, 2023
Wang X, Yu G.
europepmc   +1 more source

Mitochondrial CircRNA CircMT‐RNR2 Safeguards Antioxidant Defense to Support Fibroblast Functions in Wound Repair

Advanced Science, EarlyView.
CircMT‐RNR2 promotes wound healing by enhancing fibroblast proliferation, migration, contraction, and extracellular matrix (ECM) production. It sustains mitochondrial redox balance by stabilizing the antioxidant protein PRDX3, thereby reducing ROS‐induced damage. In diabetic foot ulcers, hypoxia, hyperglycemia, and reduced FGF2 and EGF expression lower
Guanglin Niu, Jennifer Geara, Yongjian Chen, Lihua Luo, Yanwei Xiao, Zhuang Liu, Margaux Gaborieau, Ling Pan, Edmund Loh, Dongqing Li, Pehr Sommar, Aoxue Wang, Xiaowei Zheng, Ning Xu Landén   +13 more
wiley   +1 more source

Integrative analysis of single-cell and microarray data reveals SPI1-centered macrophage regulatory signatures in ulcerative colitis. [PDF]

Front Genet
Yu Y, Yu C, Dai S, Liu Y, Hu L, Lu W.
europepmc   +1 more source

Exploring the pathogenesis of colorectal carcinoma complicated with hepatocellular carcinoma via microarray data analysis. [PDF]

Front Pharmacol, 2023
Gao T, Li M, Wu D, Xiao N, Huang D, Deng L, Yang L, Tian C, Cao Y, Zhang J, Gu J, Yu Y.   +11 more
europepmc   +1 more source

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Analysis of the molecular mechanisms of ulcerative colitis and atherosclerosis by microarray data. [PDF]

Sci Rep
Wu M, Liu D, Xiong X, Su Q, Xiang Y, Shen L, An Z, Yang X.   +7 more
europepmc   +1 more source

Meta-Analysis of Microarray Data and Their Utility in Dissecting the Mapped QTLs for Heat Acclimation in Rice. [PDF]

Plants (Basel), 2023
Singh BK, Venkadesan S, Ramkumar MK, Shanmugavadivel PS, Dutta B, Prakash C, Pal M, Solanke AU, Rai A, Singh NK, Mohapatra T, Sevanthi AM.   +11 more
europepmc   +1 more source

Multi‐View Biomedical Foundation Models for Molecule‐Target and Property Prediction

Advanced Science, EarlyView.
Molecular foundation models can provide accurate predictions for a large set of downstream tasks. We develop MMELON, an approach that integrates pre‐trained graph, image, and text foundation models and validate our multi‐view model on over 120 tasks, including GPCR binding.
Parthasarathy Suryanarayanan, Yunguang Qiu, Shreyans Sethi, Diwakar Mahajan, Hongyang Li, Yuxin Yang, Elif Eyigoz, Aldo Guzmán‐Sáenz, Daniel E. Platt, Timothy H. Rumbell, Kenney Ng, Sanjoy Dey, Myson Burch, Bum Chul Kwon, Pablo Meyer, Feixiong Cheng, Jianying Hu, Joseph A. Morrone   +17 more
wiley   +1 more source

ACG-SFE: Adaptive cluster-guided simple, fast, and efficient feature selection for high-dimensional microarray data in binary classification. [PDF]

PLoS One
Tye YW, Chew X, Yusof UK, Tulpar S.
europepmc   +1 more source

Genetic algorithm-based feature selection with manifold learning for cancer classification using microarray data. [PDF]

BMC Bioinformatics, 2023
Wang Z, Zhou Y, Takagi T, Song J, Tian YS, Shibuya T.   +5 more
europepmc   +1 more source