Evolutionary Genomics of Human Gut Bacteria: Ecological Plasticity Across the Mutualism-Pathogenicity Spectrum. [PDF]
Ramadan YN +7 more
europepmc +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Henipaviruses at the threshold: preparedness in the era of recurrent spillover. [PDF]
Wang X, Zhang W.
europepmc +1 more source
Enzymatic DNA Reaction Networks for Orchestrating Stimuli‐Dependent Temporal Molecular Pulse
We present an enzymatic DNA reaction network (EDRN) that encodes nucleic‐acid targets in time, converting inputs into a universal strand and then into programmable transient fluorescence pulses. With time‐color multiplexing, EDRN enables single‐tube high‐plex nucleic acid detection and shows strong agreement with clinical sequencing across 32 specimens.
Jiayu Yang +7 more
wiley +1 more source
Soil pH and Nitrogen Content Drive the Succession of RubisCO-Harboring Microbial Communities Across <i>Picea asperata</i> Plantation Ages. [PDF]
Li D +6 more
europepmc +1 more source
Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma +11 more
wiley +1 more source
The interaction between microbes and cytokines in cancer: unraveling the underlying effects. [PDF]
Li Y, Zhu Y, Zhang F, Huang C, Wang Z.
europepmc +1 more source
Machine‐Learning Microfluidic Minute‐Scale Microorganism Metrics Monitoring(M6)
ABSTRACT On‐site monitoring of microorganisms remains challenging because of low concentrations, strong background interference, and dynamic aerosol diffusion, particularly for aerosol‐transmitted pathogens. Here, we report a rapid detection platform that integrates a Puri‐focusing microfluidic chip, electrochemical impedance spectroscopy (EIS), and ...
Ning Yang +14 more
wiley +1 more source
Life of Microbes describes the process of growing bacterial samples from soil samples taken not only at Johnson County Community College Campus but your own back yard.
Hoskins, Meagan
core
Thermal and solutal analysis of oxytactic microbes in bioconvection slip flow of trihybrid nanofluid with activation energy using artificial neural network. [PDF]
Abbas M +5 more
europepmc +1 more source

