Results 1 to 10 of about 5,803 (234)

Adherent-Invasive E. Coli – Induced Specific IgA Limits Pathobiont Localization to the Epithelial Niche in the Gut

Frontiers in Microbiology, 2023
Background and aimAdherent-invasive E. coli (AIEC) has been identified as a pathobiont associated with Crohn’s disease (CD), that prefers to grow in inflammatory conditions.
Masashi Matsushima, Motoki Kaneko, Hiroko Nagao-Kitamoto   +2 more
exaly   +4 more sources

Role of the Upper Airway Microbiota in Respiratory Virus and Bacterial Pathobiont Dynamics in the First Year of Life

Nature Communications
The mechanisms by which respiratory viruses predispose to secondary bacterial infections remain poorly characterized. Using 2,409 nasopharyngeal swabs from 300 infants enrolled in a prospective cohort study in Botswana, we perform a detailed analysis of ...
Jillian H Hurst, Matthew S Kelly, Andrew P Steenhoff   +2 more
exaly   +3 more sources

Gestational diabetes alters subgingival pathobiont composition [PDF]

Acta Odontologica Scandinavica
Objective: This cross-sectional study assesses the relationship between gestational diabetes mellitus (GDM) and periodontal dysbiosis by evaluating specific periodontal pathobionts (Porphyromonas gingivalis, Prevotella intermedia, Tannerella forsythia ...
Fatih Cömert, Funda Yalçın, Nursen Topçuoğlu, Oya Kaya-Şimşek, Oya Demirci, Silvi Domnori, Ulku Baser   +6 more
doaj   +3 more sources

Autoimmune disease-associated pathobionts: mechanisms and therapeutic potential of phage-based approaches [PDF]

Frontiers in Immunology
The gut microbiota is a critical regulator of systemic immune homeostasis; accumulating evidence implicates specific commensal bacteria, termed “pathobionts,” in autoimmune disease pathogenesis.
Kentaro Kuzuya, Yuichi Maeda, Yuichi Maeda, Kenji Funakoshi, Yumiko Mizuno, Yumiko Mizuno, Kosuke Fujimoto, Kosuke Fujimoto, Kosuke Fujimoto   +8 more
doaj   +2 more sources

Expansion resistance against genotoxic E. coli: protective effects of Bifidobacterium pseudolongum in DSS-induced colitis in mice [PDF]

Frontiers in Microbiology
IntroductionUlcerative colitis is a chronic inflammatory disease affecting the colon, and its incidence is rising worldwide. Significant alterations to the composition and function of the gut microbiota that favor the expansion of pathobionts have been ...
Ayodeji Samuel Ajayi, Gabriela Fragoso, Annie Calvé, Claire Gerkins, Thibault Maumy, Claire McCartney, Manuela M. Santos, Manuela M. Santos   +7 more
doaj   +2 more sources

Bovine Respiratory Mycoplasmas and the Commensal–Pathogen Continuum: A Systematic Review of Vaccines and Diagnostic Approaches [PDF]

Animals
Mycoplasmas colonise bovine respiratory mucosal surfaces as commensal organisms, yet certain species may contribute to bovine respiratory disease complex (BRDC) when host and environmental conditions favour pathogenic expression.
Gebremeskel Mamu Werid, Yassein M. Ibrahim, Ashenafi Kiros Wubshet, Joshua W. Aleri, Farhid Hemmatzadeh, Kiro R. Petrovski   +5 more
doaj   +2 more sources

Haemophilus influenzae: Imposter, Mucosal Pathobiont, and Model Organism.

Journal of Bacteriology
Haemophilus influenzae has served as a model organism in numerous ways over the last century. The relationship between H. influenzae and the influenza virus provided early insights into bacterial superinfections as a complication of viral infection ...
Joseph W St Geme, Katelyn Amero
exaly   +3 more sources

In-Vitro Susceptibility of Gut Pathobiont Associated With Microbial Translocation to Cotrimoxazole and Antiretroviral

Scientific African, 2019
The human gut microbiota consortium consists of microorganisms that are sensitive to some antimicrobial agents. These gut microbiota are essential in upholding a healthy gut environment. A few of the gut microbiota has been described as pathobiont, which
Simon Eyongabane Ako, Thumamo Benjamin Pokam   +1 more
exaly   +3 more sources

Dysbiosis From a Microbial and Host Perspective Relative to Oral Health and Disease

Frontiers in Microbiology, 2021
The significance of microbiology and immunology with regard to caries and periodontal disease gained substantial clinical or research consideration in the mid 1960's.
Carla Cugini, Narayanan Ramasubbu, Vincent K. Tsiagbe, Daniel H. Fine   +3 more
doaj   +1 more source

Absence of Bacteria Permits Fungal Gut-To-Brain Translocation and Invasion in Germfree Mice but Ageing Alone Does Not Drive Pathobiont Expansion in Conventionally Raised Mice

Frontiers in Aging Neuroscience, 2022
Age-associated changes in the structure of the intestinal microbiome and in its interaction with the brain via the gut-brain axis are increasingly being implicated in neurological and neurodegenerative diseases.
Aimée Parker, Steve A. James, Catherine Purse, Arlaine Brion, Andrew Goldson, Andrea Telatin, David Baker, Simon R. Carding   +7 more
doaj   +1 more source