Results 231 to 240 of about 683,305 (299)

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

Advanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang, Qing Wu, Hao‐Long Zeng, Yin Shen, Hong‐Han Zhang, Jun Gong, Qi Zhang, Jia‐Zhao Xie, Da‐Wei Ye, Zi‐Yong Sun, Zhong‐Chun Liu, Li‐Ming Cheng, Di Li   +12 more
wiley   +1 more source

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

Advanced Science, EarlyView.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai, Taipeng Sun, Mengzhen Feng, Gang Chen, Junchi Zhou, Hong Zhuang, Dan Wang, Ying Chen, Zhen Cheng, Zhi Xu, Xiao Zheng, Xueli Zhang, Yonggui Yuan   +12 more
wiley   +1 more source

From Plato to Pareto: Defining the shape of infection's disease space. [PDF]

Sci Adv
Lebel Y, Gupta AS, Chevée V, Alon U, Schneider DS.   +4 more
europepmc   +1 more source

Extracellular Vesicle‐Delivered tRF‐His‐GTG‐1 Reprograms Neutrophil Lipophagy and Triggers Inflammation in COVID‐19

Advanced Science, EarlyView.
This study identifies platelet‐derived extracellular vesicles as key immunometabolic regulators in COVID‐19. The delivery of tRF‐His‐GTG‐1 to neutrophils activates TLR8mTOR signaling, disrupts lipophagy, and amplifies NET‐mediated inflammation. Importantly, targeting this axis restores neutrophil homeostasis, offering a potential therapeutic strategy ...
Tsai‐Ling Liao, Po‐Yu Liu, Yi‐Ming Chen, Kuo‐Tung Tang, Hung‐Jen Liu, Der‐Yuan Chen   +5 more
wiley   +1 more source

'Science Fun Days': Opportunities for Connecting Primary School Pupils With Nature and Microbiology. [PDF]

Microb Biotechnol
Archer EJ, Whitby CB, Ferguson RMW, Clark DR, Skinner BM, Henderson DK, Solanke OS, Sturrock AM, Boreham R, McGenity TJ.   +9 more
europepmc   +1 more source

Airborne Bacterial Communities: Diversity, Survival Strategies and Functional Roles in the Atmosphere. [PDF]

Environ Microbiol Rep
Park J, Fowler SJ.
europepmc   +1 more source

Interaction of intratumoral microbiota with the tumor immune microenvironment and its impact on cancer progression. [PDF]

Front Oncol
Tingting Y, Xiaoling Z, Yu Z, Yan L, Yang L, Xueqin S, Shikai T.   +6 more
europepmc   +1 more source

Exploring the Muco-Microbiotic Interface as a Hub for Microbial Metabolites and Immune Regulation in Gastroenteric Health and Disease. [PDF]

Cells
Carista A, Gratie MI, Tornatore E, Accomando S, Tomasello G, Picone D, Burgio S, Cappello F.   +7 more
europepmc   +1 more source

Intratumoral microbiota and metabolites: dual roles in cancer progression and therapeutic opportunities. [PDF]

Cell Commun Signal
Zhai Z, Li X, Shang S, Ma S, Liang X, Yin S, Wu M, Yu J, Song Q, Chen D.   +9 more
europepmc   +1 more source

Intratumoral microbiota: synergistic reshaping of lung cancer microenvironment via inflammation and immunity. [PDF]

Front Immunol
Zhang R, Li Z, Liu X, Qiu Z, Li Y, Gao C, Guo C.   +6 more
europepmc   +1 more source