Results 101 to 110 of about 1,434,392 (277)

AS‐TLC‐Based High‐Throughput Screening Integrated with CuAAC Optimization Strategy Facilitates the Rapid Discovery of YTHDC1 Inhibitor

Advanced Science, EarlyView.
We developed Affinity Selection Thin‐Layer Chromatography (AS‐TLC) as a method for high‐throughput screening (HTS) of compound mixtures. Furthermore, we integrated activity assays with AS‐TLC and identified a YTH domain‐containing protein 1 (YTHDC1) inhibitor. Building on this hit, we applied copper(I)‐catalyzed azide–alkyne cycloaddition (CuAAC) click
Mingchen Wang, Shuiping Fu, Ye Xu, Jia Gao, Jiwei Ren, Xu Yang, Hesong Xu, Ge Sun, Yanjie Li, Yanlin Wang, Lu Jin, Peijuan Chen, Ying Xu, Jianhao Li, Hua Lin, Chujiao Hu, Kaixian Chen, Huan Xiong, Cheng Luo, Shijie Chen   +19 more
wiley   +1 more source

Sequential Patterning of Photoresponsive Hydrogels Directs Crypt Fission and Reveals the Role of Epithelial Curvature on Fission Symmetry

Advanced Science, EarlyView.
Deterministic crypt fission is achieved in intestinal organoids using photopatternable hydrogels with spatiotemporal control. Daughter‐crypt symmetry is shown to depend on parent‐crypt geometry and epithelial curvature, while myosin‐dependent mechanosensing links tissue shape to regenerative outcomes.
Delaney L. McNally, Kaustav Bera, Nolan R. Petrich, Alex Khang, Marilyne Coulombe, David Castillo‐Azofeifa, Ophir D. Klein, Peter J. Dempsey, Kristi S. Anseth   +8 more
wiley   +1 more source

Aspects of the breeding biology of the Kittiwake gull Rissa tridactyla at Marsden Bay, Tyne and Wear [PDF]

, 1993
Although much research has been undertaken into the status and biology of the Kittiwake Rissa tridactyla studies of a colony over an extended period are scarce with the notable exception of the North Shields colony for which 31 years of data were ...
Strowger, John
core  

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

Advanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia, Yuwei Sun, Jialin Wang, Yike Liu, Lu Wang, Shiqi Jiang, Gaiyan Bai, Ruijing Zhang, Yu Zhang, Rongwei Kou, Danna Wang, Beita Zhao, Junjie Yi, Yu Fu, Xiaoning Liu, Xuebo Liu   +15 more
wiley   +1 more source

A Huaxian Formula Nanoformulation Confers Protection Against Acute Radiation‐Induced Lung Injury by Targeting Ferroptosis

Advanced Science, EarlyView.
An inhalable, nanoengineered herbal therapy achieves protection against acute radiation‐induced lung injury via self‐assembled nanomicelle‐mediated pulmonary targeting and a previously unrecognized dual mechanism that attenuates oxidative stress while inhibiting ferroptosis in alveolar epithelial cells.
Li Quan, Junyang Chen, Xingmin Chen, Zengyi Fang, Yuanzhen Mi, Pingjin Zou, Shunlian Fu, Huakang Li, Ke Xu, Bing Lin, Jinyi Lang, Meihua Chen   +11 more
wiley   +1 more source

Microbial Safety of Black Summer Truffle Collected from Sicily and Umbria Regions, Italy

Journal of Food Quality and Hazards Control, 2021
Background: Tuber aestivum Vittad., known as black summer truffle, represents high-value food especially used as garnishment in nouvelle cuisine. The aim of this study was to investigate on the viable microbial populations associated with T.
F. Cirlincione, N. Francesca, L. Settanni, D. Donnini, G. Venturella, M.L. Gargano   +5 more
doaj  

Dish Washing Techniques on Colony Count of Cutleries in Food (Coto) Stall in Ternate

There were two food poisoning incidences in 2023 in Ternate City. The presence of germs, can cause illness and even poisoning. Microbial load on cutleries could be caused by improper dish washing.
Sidebang, Purnama, Sakriani, Sakriani, Melinda, Aulia, Sangadjisowohy, Idayani   +3 more
core  

Uji Cemaran Mikroba Pada Infus Dextrosa Sesudah Pakai Dengan Metode Angka Lempeng Total (ALT) Dan Angka Kapang Khamir (AKK) Di Rumah Sakit “Y” Di Ponorogo

, 2017
Nurhayati, Alfiyah. 2017. “Microbial Contamination Test on Used Infusion Using Method of Total Plate Count and Kapang Khamir Count at “Y” Hospital in Ponorogo “.Scientific papers.
Nurhayati, Alfiyah
core  

Fermented vegetables metavirome - microbial enumeration

This dataset contains the microbial enumeration and pH of twelve fermented vegetables: four cabbages (sauerkraut), four carrots, and four turnips (sauerruben).
Chaillou, Stéphane, LE MARREC, CLAIRE, Cantuti Gendre, Julia, Omhover-Fougy, Lysiane, Dugat-Bony, Eric, OMHOVER, FOUGY, LYSIANE, Landaud, Sophie, CANTUTI, GENDRE, JULIA, Le Hénaff-Le Marrec, Claire   +8 more
core   +1 more source

Percentage cell reduction curves based on colony count method vs. XTT assay.

, 2013
Percentage cell reduction curves of P. aeruginosa biofilm cells upon exposure to the 20 kHz plasma jet. The dotted line is based on the standard colony count method whereas the solid line is based on the XTT assay.
Garry Laverty (309200), Mahmoud Y. Alkawareek (309198), Qais Th. Algwari (309199), Deborah O'Connell (309203), Sean P. Gorman (309201), Brendan F. Gilmore (309204), William G. Graham (309202)   +6 more
core   +1 more source