Results 31 to 40 of about 214,177 (262)

Microbial core communities in activated sludge plants are strongly affected by immigration and geography

Environmental Microbiome
Background The microbiota in wastewater treatment plants (WWTPs) and incoming wastewater is critical for the treatment process, the preservation of natural ecosystems and human health, and for the recovery of resources and achievement of sustainability ...
Sofie Zacho Vestergaard, Giulia Dottorini, Miriam Peces, Admir Murguz, Morten Kam Dahl Dueholm, Marta Nierychlo, Per Halkjær Nielsen   +6 more
doaj   +1 more source

Microbial Community Structure and Functional Potential Along a Hypersaline Gradient

Frontiers in Microbiology, 2018
Salinity is one of the strongest environmental drivers of microbial evolution and community composition. Here we aimed to determine the impact of salt concentrations (2.5, 7.5, and 33.2%) on the microbial community structure of reclaimed saltern ponds ...
Jeffrey A. Kimbrel, Jeffrey A. Kimbrel, Nicholas Ballor, Nicholas Ballor, Yu-Wei Wu, Yu-Wei Wu, Maude M. David, Terry C. Hazen, Terry C. Hazen, Blake A. Simmons, Blake A. Simmons, Steven W. Singer, Steven W. Singer, Janet K. Jansson, Janet K. Jansson   +14 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

The predicted secreted proteome of activated sludge microorganisms indicates distinct nutrient niches

mSystems
In wastewater treatment plants (WWTPs), complex microbial communities process diverse chemical compounds from sewage. Secreted proteins are critical because many are the first to interact with or degrade external (macro)molecules.
Kenneth Wasmund, Caitlin Singleton, Morten Kam Dahl Dueholm, Michael Wagner, Per Halkjær Nielsen   +4 more
doaj   +1 more source

Enhanced Methanization of Long-Chain Fatty Acid Wastewater at 20°C in the Novel Dynamic Sludge Chamber–Fixed Film Bioreactor

Frontiers in Energy Research, 2020
Lipid-containing wastewaters, such as those arising from dairy processing, are frequently discharged at temperatures ≤ 20°C. Their valorization at low ambient temperatures offers opportunities to expand the application of high-rate anaerobic wastewater ...
Suniti Singh, Suniti Singh, Suniti Singh, Suniti Singh, B. Conall Holohan, B. Conall Holohan, Simon Mills, Juan Castilla-Archilla, Marika Kokko, Jukka Rintala, Piet N. L. Lens, Piet N. L. Lens, Gavin Collins, Vincent O’Flaherty   +13 more
doaj   +1 more source

Application of ecosystem-specific reference databases for increased taxonomic resolution in soil microbial profiling

Frontiers in Microbiology, 2022
Intensive agriculture systems have paved the way for a growing human population. However, the abundant use of mineral fertilizers and pesticides may negatively impact nutrient cycles and biodiversity.
Christina Karmisholt Overgaard, Ke Tao, Sha Zhang, Bent Tolstrup Christensen, Zuzana Blahovska, Simona Radutoiu, Simon Kelly, Morten Kam Dahl Dueholm   +7 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Application of antibiotics for the selective isolation of previously uncultured species from activated sludge

Microbiology Spectrum
The microbial communities in activated sludge (AS) drive pollutant degradation and nutrient transformation into biomass and gaseous products, while also enabling resource recovery processes.
Stefania Andrea Rosso Villanelo, Sofie Zacho Vestergaard, Lei Liu, Yu Yang, Inge Søkilde Pedersen, Per Halkjær Nielsen, Morten Kam Dahl Dueholm   +6 more
doaj   +1 more source