Results 181 to 190 of about 11,690,458 (246)

Reframing the Gut–Brain Axis: The Gut Wall as a Neural Immune Interface in Multiple Sclerosis and Autoimmune Neurological Diseases

open access: yesAnnals of Neurology, EarlyView.
Gut wall physiology in multiple sclerosis (MS) and autoimmune neurologic diseases remains underexplored but may span gut barrier dysfunction, enteric glial targeting, mucosal immune dysregulation, and autoimmune targets within the enteric nervous system (ENS).
Federico Montini   +4 more
wiley   +1 more source

Microbial community structure and source contribution to the early neovaginal microbiota following penile inversion vaginoplasty. [PDF]

open access: yesFront Cell Infect Microbiol
von Bargen L   +5 more
europepmc   +1 more source

Evolutionary, Functional and Mechanistic Characterisation of Microbial Terpene Synthase‐Like Genes From Springtails

open access: yesAngewandte Chemie International Edition, EarlyView.
A genome analysis revealed the presence of many bacterial‐type terpene synthases in springtails. Four enzymes from Sinella curviseta were functionally characterised, resulting in the isolation of several compounds including sinellene ether, the first diterpene ether identified from a terpene synthase that represents a novel skeleton.
Min Wang   +5 more
wiley   +1 more source

Microbial community structure and functional potential in a long-term uranium-nickel contaminated ecosystem. [PDF]

open access: yesFront Microbiol
Chukwujindu C   +5 more
europepmc   +1 more source

Synthesis and Activity‐Based Protein Profiling Identifies Aldo‐Keto Reductase 1C3 as Target Protein of Myxoglucamides

open access: yesAngewandte Chemie International Edition, EarlyView.
Myxoglucamide A—a novel glycolipopeptide isolated from myxobacteria—was synthesized, and activity‐based protein profiling identified aldo‐keto reductase 1C3 (AKR1C3) as its main target in human cells. Structure‐activity relationship studies, together with biophysical characterization and X‐ray crystallography, elucidated the structural basis of AKR1C3 ...
Thomas Siemon   +9 more
wiley   +1 more source

Shaping of microbial community structure and function by effluent-derived dissolved organic matter in a receiving river across seasons. [PDF]

open access: yesEco Environ Health
Shao B   +11 more
europepmc   +1 more source

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