Results 141 to 150 of about 361,751 (317)

High-Level Production of NMN in Escherichia coli Through Co-Utilization of Glucose and Glycerol

Microorganisms
Nicotinamide mononucleotide (NMN), a direct precursor of the essential coenzyme nicotinamide adenine dinucleotide (NAD+), confers anti-aging effects and multiple health benefits.
Jiajia Gan, Xiuzhen Chen, Yongzhi He, Yanfeng Zhang, Jin Zhong, Zhiyang Dong   +5 more
doaj   +1 more source

Editorial for the Special Issue “Microbial Diversity and Microbial Resistance”

Biology
In the beginning, it was diversity—or so evolutionary biology suggest when interpreting how and why antibiotic production began on Earth [...]
Chrysoula (Chrysa) Voidarou, Athina Tzora   +1 more
openaire   +3 more sources

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Microbial Biodiversity of Thermophilic Communities in Hot Mineral Soils of Tramway Ridge, Mt. Erebus, Antarctica

, 2007
Only a few studies have looked at microbial biogeography in soils and whether microorganisms are endemic to an area is still debatable. Tramway Ridge, a geothermal area on Mount Erebus, Antarctica, provides a unique opportunity due to its isolation and ...
Soo, Rochelle M.
core  

Microbial community composition of transiently wetted Antarctic Dry Valley soils

, 2015
During the summer months, wet (hyporheic) soils associated with ephemeral streams and lake edges in the Antarctic Dry Valleys (DVs) become hotspots of biological activity and are hypothesized to be an important source of carbon and nitrogen for arid DV ...
Stephen C. Cary, Capone, Douglas G., Edward J. Carpenter, Gunderson, Troy E., Joëlle Tirindelli, Parker, Alexander E., Sohm, Jill A., Carpenter, Edward J., Troy E. Gunderson, Stephen Craig Cary, Niederberger, Thomas D., Douglas G. Capone, Jill A. Sohm, Joelle eTirindelli, Thomas D. Niederberger, Cary, S. Craig, Alexander E. Parker, Tirindelli, Joëlle, Douglas G Capone, Thomas D. Neiderberger, Thomas D. Niederberger   +20 more
core   +1 more source

Climate Change Threatens Micronutrient Density of European Winter Wheat

Advanced Science, EarlyView.
Micronutrients are vital for human health. Wheat is a major staple crop and a significant source of minerals and B‐vitamins. The impact of climate change on their content remains largely unknown. We evaluated micronutrient levels in European winter wheat grown under historical and projected climate conditions. Our findings indicate that future climates
Da Cao, Jennifer Michel, Eline Lorer, Markus Weinmann, Jacques Le Gouis, Claire Léon, Sibille Perrochon, David Alvarez, Vincent Leemans, Iñaki Balanzategui Guijarro, Jordi Moya Laraño, Sara Sánchez Moreno, Symanczik Sarah, Waibel Matthias, Hervé Vanderschuren, Cécile Thonar, Pierre Delaplace, Dominique Van Der Straeten   +17 more
wiley   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao, Shuangya Fan, Juan Xu, Zhen Xu, Chen Peng, Junxing Qu, Ziqian Bing, Shizhen Zhou, Sunan Shen, Guifang Xu, Yue Zhao, Tingting Wang   +11 more
wiley   +1 more source

Time‐Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism

Advanced Science, EarlyView.
This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia, Chenfei Kong, Xiaoming Zhao, Naixu Shi, Jinlan Jiang, Ping Li   +5 more
wiley   +1 more source

Functional diversification of epidithiodiketopiperazine methylation and oxidation towards pathogenic fungi

Mycology
The genus Trichoderma plays a vital role in agriculture by promoting plant growth, enhancing nutrient uptake, and protecting crops from pathogens through biocontrol mechanisms.
Shengquan Zhang, Peng-Lin Wei, Yuanyuan Li, Zedong Ren, Jie Fan, Wen-Bing Yin   +5 more
doaj   +1 more source

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source