Results 111 to 120 of about 346,542 (364)
Advanced Materials, EarlyView.Convergence drawing is used to create flexible, microscale, multifunctional fiber‐based neural probes. Optimized materials selection enables individual devices to perform neural recording, electrical stimulation, optogenetics, fiber photometry, fluid delivery, and voltammetric neurotransmitter detection in rodents.
Nicolette Driscoll +16 more
wiley +1 more source
Spatial heterogeneity in drug concentrations can facilitate the emergence of resistance to cancer therapy [PDF]
, 2014 Acquired resistance is one of the major barriers to successful cancer therapy. The development of resistance is commonly attributed to genetic heterogeneity. However, heterogeneity of drug penetration of the tumor microenvironment both on the microscopic level within solid tumors as well as on the macroscopic level across metastases may also contribute
arxiv +1 more source
Bacterial Biofilm and its Clinical Implications [PDF]
, 2018 Microbial biofilm created huge burden in treatment of both community and hospital infections. A biofilm is complex communities of bacteria attached to a surface or interface enclosed in an exopolysaccharide matrix and protected from unfavorable ...
Shakibaie, Prof
core
High‐Resolution Patterned Delivery of Chemical Signals From 3D‐Printed Picoliter Droplet Networks
Advanced Materials, EarlyView.3D‐printed picoliter droplet networks have been fabricated that control gene expression in bacterial populations by releasing chemical signals with precise spatial definition and high temporal resolution. This system of effector release is widely applicable, offering diverse applications in biology and medicine.
Jorin Riexinger +7 more
wiley +1 more source
AMP0: Species-Specific Prediction of Anti-microbial Peptides using Zero and Few Shot Learning [PDF]
arXiv, 2019 The evolution of drug-resistant microbial species is one of the major challenges to global health. The development of new antimicrobial treatments such as antimicrobial peptides needs to be accelerated to combat this threat. However, the discovery of novel antimicrobial peptides is hampered by low-throughput biochemical assays. Computational techniques
arxiv
Deletion of AIF1 but not of YCA1/MCA1 protects Saccharomyces cerevisiae and Candida albicans cells from caspofungin-induced programmed cell death [PDF]
, 2014 Caspofungin was the first member of a new class of antifungals called echinocandins to be approved by a drug regulatory authority. Like the other echinocandins, caspofungin blocks the synthesis of β(1,3)-D-glucan of the fungal cell wall by inhibiting the
Austriaco, Nicanor +5 more
core +3 more sources
A Bio‐Inspired Perspective on Materials Sustainability
Advanced Materials, EarlyView.This perspective discusses natural materials as inspiration for sustainable engineering designs and the processing of materials. First, circularity, longevity, parsimony, and activity are presented as essential material paradigms. The perspective then uses many examples of natural and technical materials to introduce principles such as oligo ...
Wolfgang Wagermaier +2 more
wiley +1 more source
Mining Selected Metagenomes/metatranscriptomes for Biosynthetic Gene Clusters and Antimicrobial Resistance Genes [PDF]
, 2021 Antimicrobial resistance is one of the serious global challenges in the current century. The fact that resistance genes transfer between bacteria, coupled with the fact that the world is connected through complex dynamics. Studying microbial behavior and
Yamany, Ahmed
core +1 more source
Materials Advances in Devices for Heart Disease Interventions
Advanced Materials, EarlyView.This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra +11 more
wiley +1 more source