Results 211 to 220 of about 195,207 (265)
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Microbial resistance to drug therapy: A review
American Journal of Infection Control, 1997Microbial resistance to the antimicrobials in standard use is becoming more prevalent. A historical perspective frames further discussion. Bacterial resistance is most common, but resistance has been identified in fungi, viruses, and parasites. Resistance is a complex phenomenon that involves the microorganism, the environment, and the patient ...
F L, Cohen, D, Tartasky
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Microbial Development of Drug Resistance: Mechanisms and Clinical Significance
CRC Critical Reviews in Clinical Laboratory Sciences, 1975Bacteria have demonstrated a disconcerting ability to develop resistance to antimicrobial agents nearly as quickly as new compounds become available. During the past two decades the molecular bases of several types of resistance have been elucidated.
Ruth M. Lawrence +2 more
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Exploring Microbial Nanotoxicity Against Drug Resistance in Bacteria
2021The growing threat of antimicrobial resistance on human health urgently calls for the need to look for novel solutions to mitigate the grave effect of this global problem and save thousands of lives each year. Nanotechnology is an emerging area that is expected to be able to have solutions toward containing the rise and spread of multidrug-resistant ...
Rajeshwari Sinha +2 more
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The Design of New Drugs That Resist Microbial Inactivation
Clinical Infectious Diseases, 1979Several possible strategems for overcoming the development of bacterial resistance are discussed. The design of new drugs that resist microbial inactivation is reviewed, with particular emphasis on the aminoglycoside and beta-lactam antibiotics. Examples of alteration of the inactivation site, decreased enzyme affinity, steric hindrance of enzymic ...
B G, Christensen +2 more
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Microbial Pathogenesis and Antimicrobial Drug Resistance
2020Antimicrobial drug resistance has become a serious threat and it caused the death of 700,000 individuals in 2016. Gram-negative bacteria such as Acinetobacter, Pseudomonas, Enterobacter spp. Enterococcus faecium, Staphylococcus aureus, and Klebsiella pneumoniae are insensitive to antibiotics. E. faecium, S. aureus, K.
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1989
Most often when the subject of antimicrobial resistance is discussed, the organizational emphasis is on individual antimicrobial agents or groups of agents. Thus we tend to see discussion of resistance to f3-lactams, tetracyclines, amino glycosides etc.
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Most often when the subject of antimicrobial resistance is discussed, the organizational emphasis is on individual antimicrobial agents or groups of agents. Thus we tend to see discussion of resistance to f3-lactams, tetracyclines, amino glycosides etc.
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Microbial fermentation-derived inhibitors of efflux-pump-mediated drug resistance
Il Farmaco, 2001A library of 85000 microbial fermentation extracts was screened for inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa and Candida albicans. New compounds EA-371alpha and EA-371delta were isolated and demonstrated to be potent and specific inhibitors of the MexAB-OprM pump in P. aeruginosa.
M D, Lee +8 more
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Quorum sensing and microbial drug resistance.
Yi chuan = Hereditas, 2017Microbial drug resistance has become a serious problem of global concern, and the evolution and regulatory mechanisms of microbial drug resistance has become a hotspot of research in recent years. Recent studies showed that certain microbial resistance mechanisms are regulated by quorum sensing system.
Yu-fan, Chen +5 more
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Drug-resistant fungus joins growing list of microbial threats
American Journal of Health-System Pharmacy, 2012Public health officials say that the emergence in the United States of a deadly multidrug-resistant fungus first reported in Asia is an unwelcome but not unexpected development. “In our interconnected world, a health threat anywhere is a threat everywhere,” said Melinda Neuhauser, the ...
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Microbial Natural Products: Exploiting Microbes Against Drug-Resistant Bugs
2019The unsystematic and incoherent usage of antibiotics has led to an exceptional challenge for mankind, due to the development of resistance in pathogens toward the available drugs by a phenomenon known as multidrug resistance (MDR). By year 2050, the drug-resistant infections across the globe are predicted to reach an alarming number of ten million ...
Suriya Rehman +3 more
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