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Evaluating antimicrobial resistance and clinical outcomes in surgical ICU using a machine learning perspective: a retrospective observational study. [PDF]

open access: yesBMC Infect Dis
Ziaian B   +15 more
europepmc   +1 more source
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Drug repurposing to overcome microbial resistance

Drug Discovery Today, 2022
Infections are a growing global threat, and the number of resistant species of microbial pathogens is alarming. However, the rapid development of cross-resistant or multidrug-resistant strains and the development of so-called 'superbugs' are in stark contrast to the number of newly launched anti-infectives on the market. In this review, I summarize the
openaire   +2 more sources

Microbial Drug Resistance

1955
Publisher Summary It is unfeasible and unnecessary to coerce the complex biological events contributing to the origin of resistance into a single theory. Experimental evidence suggests that a few models define most examples of resistance development, particularly if the models are so combined as to provide either genotypic or phenotypic alterations ...
V, BRYSON, W, SZYBALSKI
openaire   +2 more sources

Microbial and viral drug resistance mechanisms

Trends in Microbiology, 2002
Microorganisms and viruses have developed numerous resistance mechanisms that enable them to evade the effect of antimicrobials and antivirals. As a result, many have become resistant to almost every available means of treatment. This problem, although not new, is becoming increasingly acute and it is now clear that a fundamental understanding of the ...
Kenneth S, McKeegan   +2 more
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Biocides, drug resistance and microbial evolution

Current Opinion in Microbiology, 2001
Antimicrobial biocides are widely used in critical human health situations in which rigorous infection control is needed. Increasingly, biocidal agents are being marketed for home use, although there is little evidence that they significantly improve home hygiene. Biocide resistance mechanisms share many themes with antibiotic resistance mechanisms.
D G, White, P F, McDermott
openaire   +2 more sources

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