Results 271 to 280 of about 39,725 (303)

Experimental evolution and the dynamics of adaptation and genome evolution in microbial populations [PDF]

open access: yesISME Journal, 2017
Abstract Evolution is an on-going process, and it can be studied experimentally in organisms with rapid generations. My team has maintained 12 populations of Escherichia coli in a simple laboratory environment for >25 years and 60 000 generations. We have quantified the dynamics of adaptation by natural selection, seen some of the
Richard E Lenski, Lenski Richard E
exaly   +3 more sources

Evolution of Microbial Genomics: Conceptual Shifts over a Quarter Century

Trends in Microbiology, 2021
Prokaryote genomics started in earnest in 1995, with the complete sequences of two small bacterial genomes, those of Haemophilus influenzae and Mycoplasma genitalium. During the next quarter century, the prokaryote genome database has been growing exponentially, with no saturation in sight. For most of these 25 years, genome sequencing remained limited
Eugene V Koonin   +2 more
exaly   +3 more sources

Microbial evolution: the genome, the regulome and beyond

Environmental Microbiology, 2008
Summary Experimental and computational studies show that tran-scriptional regulatory networks in both eukaryotic andprokaryotic microbes have a large amount of variationeven between closely related species. While the architec-ture of bacterial genomes is unexpectedly diverse, evenwithin short evolutionary scales, the variations in eithergene content or
Miguel, Vicente, Jesús, Mingorance
openaire   +2 more sources

Combining morphology, behaviour and genomics to understand the evolution and ecology of microbial eukaryotes [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2019
Microbial eukaryotes (protists) are structurally, developmentally and behaviourally more complex than their prokaryotic cousins. This complexity makes it more difficult to translate genomic and metagenomic data into accurate functional inferences about systems ranging all the way from molecular and cellular levels to global ecological networks.
Patrick J Keeling
exaly   +3 more sources

Horizontal Gene Transfer in Microbial Genome Evolution

Theoretical Population Biology, 2002
Horizontal gene transfer is the collective name for processes that permit the exchange of DNA among organisms of different species. Only recently has it been recognized as a significant contribution to inter-organismal gene exchange. Traditionally, it was thought that microorganisms evolved clonally, passing genes from mother to daughter cells with ...
Ravi, Jain   +3 more
openaire   +2 more sources

Evolution of transcriptional regulatory networks in microbial genomes

Current Opinion in Structural Biology, 2006
Advances in sequencing and generating high-throughput expression data have created a situation in which it is possible to integrate comparative analysis with genome-wide studies of the structure and function of regulatory systems in model organisms. Recent studies have focused on topological properties and the evolution of regulatory networks.
openaire   +2 more sources

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