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Experimental evolution and the dynamics of adaptation and genome evolution in microbial populations [PDF]
Abstract Evolution is an on-going process, and it can be studied experimentally in organisms with rapid generations. My team has maintained 12 populations of Escherichia coli in a simple laboratory environment for >25 years and 60 000 generations. We have quantified the dynamics of adaptation by natural selection, seen some of the
Richard E Lenski, Lenski Richard E
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Genomics and evolution of microbial eukaryotes [PDF]
Mark A Ragan
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Evolution of Microbial Genomics: Conceptual Shifts over a Quarter Century
Trends in Microbiology, 2021Prokaryote genomics started in earnest in 1995, with the complete sequences of two small bacterial genomes, those of Haemophilus influenzae and Mycoplasma genitalium. During the next quarter century, the prokaryote genome database has been growing exponentially, with no saturation in sight. For most of these 25 years, genome sequencing remained limited
Eugene V Koonin +2 more
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Microbial evolution: the genome, the regulome and beyond
Environmental Microbiology, 2008Summary Experimental and computational studies show that tran-scriptional regulatory networks in both eukaryotic andprokaryotic microbes have a large amount of variationeven between closely related species. While the architec-ture of bacterial genomes is unexpectedly diverse, evenwithin short evolutionary scales, the variations in eithergene content or
Miguel, Vicente, Jesús, Mingorance
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Combining morphology, behaviour and genomics to understand the evolution and ecology of microbial eukaryotes [PDF]
Microbial eukaryotes (protists) are structurally, developmentally and behaviourally more complex than their prokaryotic cousins. This complexity makes it more difficult to translate genomic and metagenomic data into accurate functional inferences about systems ranging all the way from molecular and cellular levels to global ecological networks.
Patrick J Keeling
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Horizontal Gene Transfer in Microbial Genome Evolution
Theoretical Population Biology, 2002Horizontal gene transfer is the collective name for processes that permit the exchange of DNA among organisms of different species. Only recently has it been recognized as a significant contribution to inter-organismal gene exchange. Traditionally, it was thought that microorganisms evolved clonally, passing genes from mother to daughter cells with ...
Ravi, Jain +3 more
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Understanding microbial ecology and evolution with single-cell genomics
Nature Reviews GeneticsJ Pamela Engelberts +2 more
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Evolution of transcriptional regulatory networks in microbial genomes
Current Opinion in Structural Biology, 2006Advances in sequencing and generating high-throughput expression data have created a situation in which it is possible to integrate comparative analysis with genome-wide studies of the structure and function of regulatory systems in model organisms. Recent studies have focused on topological properties and the evolution of regulatory networks.
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