Ecological perspectives on synthetic biology: insights from microbial population biology [PDF]
The metabolic capabilities of microbes are the basis for many major biotechnological advances, exploiting microbial diversity by selection or engineering of single strains. However, there are limits to the advances that can be achieved with single strains, and attention has turned toward the metabolic potential of consortia and the field of synthetic ...
Ana E Escalante+7 more
core +9 more sources
Population-based microbial computing: a third wave of synthetic biology? [PDF]
Synthetic biology is an emerging research field, in which engineering principles are applied to natural, living systems. A major goal of synthetic biology is to harness the inherent “biological nanotechnology” of living cells for the purposes of computation, production or diagnosis.
Martyn Amos
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Biological evolution: Lessons to be learned from microbial population biology and genetics
This issue is dedicated to the memory of Michel Blot, who died in a tragic accident in the French Alps in September 2002, bringing his fruitful scientific activities to a sudden end. After having completed his basic and doctoral education in population biology of eukaryotic organisms, Michel Blot joined my laboratory in 1989 with the intention of ...
Werner Arber
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Neurospora from natural populations: Population genomics insights into the Life history of a model microbial Eukaryote [PDF]
The ascomycete filamentous fungus Neurospora crassa played a historic role in experimental biology and became a model system for genetic research. Stimulated by a systematic effort to collect wild strains initiated by Stanford geneticist David Perkins ...
A Menkis+80 more
core +1 more source
Effect of irrigation with municipal water or sewage effluent on the biology of soil cores [PDF]
Abstract Microbial populations and respiratory activity are reported for topsoils (0–10 cm) of 15 cm diameter cores (depth 50 cm) of 10 pasture soils representative of soils of North Island, New Zealand, after 15 months' irrigation with either municipal tapwater or unchlorinated sewage effluent from a biological filtration plant.
Esme M. Guy+3 more
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Synthetic control of a fitness tradeoff in yeast nitrogen metabolism [PDF]
Background: Microbial communities are involved in many processes relevant to industrial and medical biotechnology, such as the formation of biofilms, lignocellulosic degradation, and hydrogen production.
Bayer, Travis S.+4 more
core +3 more sources
Improving the availability of biopesticides : an interdisciplinary research project [PDF]
There is a need for new, biologically-based crop protection products to serve as alternatives to or to complement synthetic chemical pesticides. An interdisciplinary research team from the natural and social sciences considered whether regulatory ...
Chandler, Dave+4 more
core +1 more source
Noise-driven oscillations in microbial population dynamics [PDF]
Microbial populations in the natural environment are likely to experience growth conditions very different from those of a typical laboratory xperiment. In particular, removal rates of biomass and substrate are unlikely to be balanced under realistic environmental conditions. Here, we consider a single population growing on a substrate under conditions
arxiv +1 more source
Identifying Keystone Species in the Human Gut Microbiome from Metagenomic Timeseries using Sparse Linear Regression [PDF]
Human associated microbial communities exert tremendous influence over human health and disease. With modern metagenomic sequencing methods it is possible to follow the relative abundance of microbes in a community over time.
Fisher, Charles K., Mehta, Pankaj
core +6 more sources
Extending an eco-evolutionary understanding of biofilm-formation at the air-liquid interface to community biofilms [PDF]
Growing bacterial populations diversify to produce a number of competing lineages. In the Pseudomonas fluorescens SBW25 model system, Wrinkly Spreader mutant lineages, capable of colonising the air-liquid interface of static microcosms by biofilm ...
Jerdan, Robyn+4 more
core +2 more sources