Ecological Perspectives on Synthetic Biology: Insights from Microbial Population Biology [PDF]
Frontiers in Microbiology, 2015 The metabolic capabilities of microbes are the basis for many major biotechnological advances, exploiting microbial diversity by selection or engineering of single strains.
Ana E Escalante +7 more
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Population-based microbial computing: a third wave of synthetic biology? [PDF]
International Journal of General Systems, 2014 Synthetic biology is an emerging research field, in which engineering principles are applied to natural, living systems. A major goal of synthetic biology is to harness the inherent “biological nanotechnology” of living cells for the purposes of computation, production or diagnosis.
Martyn Amos
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Biological evolution: Lessons to be learned from microbial population biology and genetics
Research in Microbiology, 2004 This issue is dedicated to the memory of Michel Blot, who died in a tragic accident in the French Alps in September 2002, bringing his fruitful scientific activities to a sudden end. After having completed his basic and doctoral education in population biology of eukaryotic organisms, Michel Blot joined my laboratory in 1989 with the intention of ...
Werner Arber
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Neurospora from Natural Populations: Population Genomics Insights into the Life History of a Model Microbial Eukaryote. [PDF]
Methods in molecular biology, 2020 The ascomycete filamentous fungus Neurospora crassa played a historic role in experimental biology and became a model system for genetic research. Stimulated by a systematic effort to collect wild strains initiated by Stanford geneticist David Perkins ...
P. Gladieux +5 more
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Engineered microbial consortia: strategies and applications
Microbial Cell Factories, 2021 Many applications of microbial synthetic biology, such as metabolic engineering and biocomputing, are increasing in design complexity. Implementing complex tasks in single populations can be a challenge because large genetic circuits can be burdensome ...
Katherine E. Duncker +2 more
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Prospects for the study of evolution in the deep biosphere [PDF]
Frontiers in Microbiology, 2012 Since the days of Darwin, scientists have used the framework of the theory of evolution to explore the interconnectedness of life on Earth and adaptation of organisms to the ever-changing environment.
Jennifer F Biddle +7 more
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Synthetic control of a fitness tradeoff in yeast nitrogen metabolism [PDF]
Journal of Biological Engineering, 2009 Background Microbial communities are involved in many processes relevant to industrial and medical biotechnology, such as the formation of biofilms, lignocellulosic degradation, and hydrogen production. The manipulation of synthetic and natural microbial
Lee Jack J +4 more
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An environment-sensitive synthetic microbial ecosystem. [PDF]
PLoS ONE, 2010 Microbial ecosystems have been widely used in industrial production, but the inter-relationships of organisms within them haven't been completely clarified due to complex composition and structure of natural microbial ecosystems. So it is challenging for
Bo Hu +3 more
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A statistical model for describing and simulating microbial community profiles.
PLoS Computational Biology, 2021 Many methods have been developed for statistical analysis of microbial community profiles, but due to the complex nature of typical microbiome measurements (e.g.
Siyuan Ma +11 more
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Exploring the microbial savanna: predator-prey interactions in the soil
Molecular Systems BiologySoils host complex multi-trophic communities with diverse, mostly microbial, predator and prey species, including numerous bacterivorous protists and bacterial prey.
Laura Sanchis Pla, Jordi van Gestel
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