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Bottom-Up Approaches to Synthetic Cooperation in Microbial Communities
Microbial cooperation pervades ecological scales, from single-species populations to host-associated microbiomes. Understanding the mechanisms promoting the stability of cooperation against potential threats by cheaters is a major question that only ...
Daniel Rodríguez Amor+1 more
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Considering Intra-individual Genetic Heterogeneity to Understand Biodiversity [PDF]
In this chapter, I am concerned with the concept of Intra-individual Genetic Hetereogeneity (IGH) and its potential influence on biodiversity estimates. Definitions of biological individuality are often indirectly dependent on genetic sampling -and vice ...
A Cárdenas-Flores+69 more
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A more significant role for insertion sequences in large-scale rearrangements in bacterial genomes
Insertion sequences (ISs) are mobile pieces of DNA that are widespread in bacterial genomes. IS movements typically involve (i) excision of the IS element, (ii) cutting of target site DNA, and (iii) IS element insertion. This process generates a new copy
Wing Y. Ngan+3 more
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Evolutionary biology for the 21st century [PDF]
New theoretical and conceptual frameworks are required for evolutionary biology to capitalize on the wealth of data now becoming available from the study of genomes, phenotypes, and organisms - including humans - in their natural environments.Molecular ...
Arnold, Stevan J.+14 more
core +5 more sources
Prospects for the study of evolution in the deep biosphere
Since the days of Darwin, scientists have used the framework of the theory of evolution to explore the interconnectedness of life on Earth and adaptation of organisms to the ever-changing environment.
Jennifer F Biddle+7 more
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Synthetic Biology Tools for Engineering Microbial Cells to Fight Superbugs
With the increase in clinical cases of bacterial infections with multiple antibiotic resistance, the world has entered a health crisis. Overuse, inappropriate prescribing, and lack of innovation of antibiotics have contributed to the surge of ...
Angel León-Buitimea+9 more
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Evolution of microbes and viruses: A paradigm shift in evolutionary biology?
When Charles Darwin formulated the central principles of evolutionary biology in the Origin of Species in 1859 and the architects of the Modern Synthesis integrated these principles with population genetics almost a century later, the principal if not ...
Eugene V. Koonin, Yuri I Wolf
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CRISPR-induced distributed immunity in microbial populations. [PDF]
In bacteria and archaea, viruses are the primary infectious agents, acting as virulent, often deadly pathogens. A form of adaptive immune defense known as CRISPR-Cas enables microbial cells to acquire immunity to viral pathogens by recognizing specific ...
Lauren M Childs+4 more
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Tiny microbes, enormous impacts: what matters in gut microbiome studies? [PDF]
Many factors affect the microbiomes of humans, mice, and other mammals, but substantial challenges remain in determining which of these factors are of practical importance. Considering the relative effect sizes of both biological and technical covariates
Debelius, Justine+5 more
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Among many factors affecting dental caries, bacteria are its initiating factor. From the perspective of ecological plaque hypothesis, the application of modern molecular biology methods enable scholars to deeply explore the relationship between the ...
ZHOU Qingnan, SHANG Jiajian
doaj +1 more source