Results 31 to 40 of about 352,795 (176)

Bottom-Up Approaches to Synthetic Cooperation in Microbial Communities

open access: yesLife, 2019
Microbial cooperation pervades ecological scales, from single-species populations to host-associated microbiomes. Understanding the mechanisms promoting the stability of cooperation against potential threats by cheaters is a major question that only ...
Daniel Rodríguez Amor   +1 more
doaj   +1 more source

Considering Intra-individual Genetic Heterogeneity to Understand Biodiversity [PDF]

open access: yes, 2019
In this chapter, I am concerned with the concept of Intra-individual Genetic Hetereogeneity (IGH) and its potential influence on biodiversity estimates. Definitions of biological individuality are often indirectly dependent on genetic sampling -and vice ...
A Cárdenas-Flores   +69 more
core   +2 more sources

A more significant role for insertion sequences in large-scale rearrangements in bacterial genomes

open access: yesmBio
Insertion sequences (ISs) are mobile pieces of DNA that are widespread in bacterial genomes. IS movements typically involve (i) excision of the IS element, (ii) cutting of target site DNA, and (iii) IS element insertion. This process generates a new copy
Wing Y. Ngan   +3 more
doaj   +1 more source

Evolutionary biology for the 21st century [PDF]

open access: yes, 2013
New theoretical and conceptual frameworks are required for evolutionary biology to capitalize on the wealth of data now becoming available from the study of genomes, phenotypes, and organisms - including humans - in their natural environments.Molecular ...
Arnold, Stevan J.   +14 more
core   +5 more sources

Prospects for the study of evolution in the deep biosphere

open access: yesFrontiers in Microbiology, 2012
Since the days of Darwin, scientists have used the framework of the theory of evolution to explore the interconnectedness of life on Earth and adaptation of organisms to the ever-changing environment.
Jennifer F Biddle   +7 more
doaj   +1 more source

Synthetic Biology Tools for Engineering Microbial Cells to Fight Superbugs

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
With the increase in clinical cases of bacterial infections with multiple antibiotic resistance, the world has entered a health crisis. Overuse, inappropriate prescribing, and lack of innovation of antibiotics have contributed to the surge of ...
Angel León-Buitimea   +9 more
doaj   +1 more source

Evolution of microbes and viruses: A paradigm shift in evolutionary biology?

open access: yesFrontiers in Cellular and Infection Microbiology, 2012
When Charles Darwin formulated the central principles of evolutionary biology in the Origin of Species in 1859 and the architects of the Modern Synthesis integrated these principles with population genetics almost a century later, the principal if not ...
Eugene V. Koonin, Yuri I Wolf
doaj   +1 more source

CRISPR-induced distributed immunity in microbial populations. [PDF]

open access: yesPLoS ONE, 2014
In bacteria and archaea, viruses are the primary infectious agents, acting as virulent, often deadly pathogens. A form of adaptive immune defense known as CRISPR-Cas enables microbial cells to acquire immunity to viral pathogens by recognizing specific ...
Lauren M Childs   +4 more
doaj   +1 more source

Tiny microbes, enormous impacts: what matters in gut microbiome studies? [PDF]

open access: yes, 2016
Many factors affect the microbiomes of humans, mice, and other mammals, but substantial challenges remain in determining which of these factors are of practical importance. Considering the relative effect sizes of both biological and technical covariates
Debelius, Justine   +5 more
core   +1 more source

Research progress on the relationship between the changes in microbial community composition of plaque and dental caries in children

open access: yes口腔疾病防治, 2021
Among many factors affecting dental caries, bacteria are its initiating factor. From the perspective of ecological plaque hypothesis, the application of modern molecular biology methods enable scholars to deeply explore the relationship between the ...
ZHOU Qingnan, SHANG Jiajian
doaj   +1 more source

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