Results 41 to 50 of about 362,544 (276)

CRISPR-induced distributed immunity in microbial populations. [PDF]

PLoS ONE, 2014
In bacteria and archaea, viruses are the primary infectious agents, acting as virulent, often deadly pathogens. A form of adaptive immune defense known as CRISPR-Cas enables microbial cells to acquire immunity to viral pathogens by recognizing specific ...
Lauren M Childs, Whitney E England, Mark J Young, Joshua S Weitz, Rachel J Whitaker   +4 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Research progress on the relationship between the changes in microbial community composition of plaque and dental caries in children

口腔疾病防治, 2021
Among many factors affecting dental caries, bacteria are its initiating factor. From the perspective of ecological plaque hypothesis, the application of modern molecular biology methods enable scholars to deeply explore the relationship between the ...
ZHOU Qingnan, SHANG Jiajian
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Environmental factors determining the epidemiology and population genetic structure of the Bacillus cereus group in the field.

PLoS Pathogens, 2010
Bacillus thuringiensis (Bt) and its insecticidal toxins are widely exploited in microbial biopesticides and genetically modified crops. Its population biology is, however, poorly understood.
Ben Raymond, Kelly L Wyres, Samuel K Sheppard, Richard J Ellis, Michael B Bonsall   +4 more
doaj   +1 more source

Archaeal ubiquity [PDF]

, 1996
In the seventeenth century, Antoine von Leeuwenhook used a simple microscope to discover that we live within a previously undetected microbial world containing an enormously diverse population of creatures. The late nineteenth and early twentieth century
Simon, Melvin I., Stein, Jeffrey L.
core  

The Community Simulator: A Python package for microbial ecology

, 2020
Natural microbial communities contain hundreds to thousands of interacting species. For this reason, computational simulations are playing an increasingly important role in microbial ecology.
Cui, Wenping, Goldford, Joshua, Marsland III, Robert, Mehta, Pankaj   +3 more
core   +1 more source

Soil biochemistry and microbial activity in vineyards under conventional and organic management at Northeast Brazil. [PDF]

, 2011
The São Francisco Submedium Valley is located at the Brazilian semiarid region and is an important center for irrigated fruit growing. This region is responsible for 97% of the national exportation of table grapes, including seedless grapes. Based on the
Adriana Mayumi Yano-Melo, Aguín O., Anaya A.L., Bengtsson J., Bettiol W., Bhattacharyya P., Bradford M.M., Brundrett M.C, Cheng X., Cochran W.G., De-Polli H., Debosz K., Dilly O., Douds Jr. D.D., Douds Jr. D.D., Feldmann F, Fernandes S.A.P., Fábio Sérgio Barbosa da Silva, Garcia C., Garcia C., Gerdemann J.W., Giovanetti M., Grisi B.M., Haynes R.J., Jeffries P., Jenkins W.R., Karagiannidis N., Leonor Costa Maia, Lovelock C.E., Lovelock C.E., Maia L.C., Marshall V.G., Matsuoka M., Miyauchi M.Y.H., Mohammad M.J., Monokrousos N., Monokrousos N., Mäder P., Nannipieri P., Natoniel Franklin de Melo, Nicácio de Oliveira Freitas, Noyd R.K., Oehl F., Pascual J.A., Pereira J.R., Pereira S.V., Purin S., Rillig M.C., Ryan M.H., Ryan M.H., Sampaio D.B., Sarangi P.K., Sattelmacher B., Schenck N.C., Schreiner R.P., Silva P.C.G., Souza R.G., Srivastava R., Stutz J.C., Swisher R., Taylor J.P., Truu M., Wardle D.A., Wright S.F., Yano-Melo A.M.   +64 more
core   +3 more sources

High-severity wildfire leads to multi-decadal impacts on soil biogeochemistry in mixed-conifer forests. [PDF]

, 2020
During the past century, systematic wildfire suppression has decreased fire frequency and increased fire severity in the western United States of America.
Bell C. W., Dillon G. K., Fox J., Johnson D. W., Parker K. W., R Development Core Team, Restaino C. R., Sun H.   +7 more
core   +2 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source