Results 51 to 60 of about 308,196 (199)

Leveraging Organ‐on‐Chip Models to Investigate Host–Microbiota Dynamics and Targeted Therapies for Inflammatory Bowel Disease

Advanced Healthcare Materials, EarlyView.
The challenges of studying inflammatory bowel disease (IBD), highlighting limitations of traditional 2D cell cultures and animal models are discussed here. It introduces human intestine organ‐on‐chip (OoC) models as a promising alternative, capable of more accurately mimicking the intestinal microenvironment.
Tim Kaden, Raquel Alonso‐Román, Johannes Stallhofer, Mark S. Gresnigt, Bernhard Hube, Alexander S. Mosig   +5 more
wiley   +1 more source

A Statistical Perspective on the Challenges in Molecular Microbial Biology [PDF]

arXiv, 2021
High throughput sequencing (HTS)-based technology enables identifying and quantifying non-culturable microbial organisms in all environments. Microbial sequences have enhanced our understanding of the human microbiome, the soil and plant environment, and the marine environment.
arxiv  

Cultural replication and microbial evolution [PDF]

, 2014
The aim of this paper is to argue that cultural evolution is in many ways much more similar to microbial than to macrobial biological evolution.
Nanay, Bence
core  

Darkness visible: reflections on underground ecology [PDF]

, 2005
1 Soil science and ecology have developed independently, making it difficult for ecologists to contribute to urgent current debates on the destruction of the global soil resource and its key role in the global carbon cycle.
Barrett D.J., Beijerinck M.W., Brookes P.C., Dunger W., Finlay B.J., Finlay B.J., Fitter A.H., Fitter A.H., Fitter A.H., Hodda M., Hyams E., Jackson R.B., Kouki J., Lambshead P.J.D., Law R., Lloyd J., Lloyd-MacGilp S.A., Manefield M., Morton J.B., Nicolson T.H., Oechel W.C., Peat H.J., Perrings C., Read D.J., Redecker D., Smith S.E., Steinbeck J., Taylor T.N., Torsvik V., Van der Heijden M.G.A., Varley J.D., Vitousek P.M., Williamson M., Williamson M., Wilson D.S., Wohl D.L., Zinke P.J.   +36 more
core   +1 more source

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray, Shehzahdi S. Moonshi, Hang Thu Ta   +2 more
wiley   +1 more source

Modeling biological networks: from single gene systems to large microbial communities [PDF]

arXiv, 2021
In this research, we study biological networks at different scales: a gene autoregulatory network at the single-cell level and the gut microbiota at the population level. Proteins are the main actors in cells, they are the building blocks, act as enzymes and antibodies. The production of proteins is mediated by transcription factors. In some cases, a
arxiv  

Soil biochemistry and microbial activity in vineyards under conventional and organic management at Northeast Brazil. [PDF]

, 2011
The São Francisco Submedium Valley is located at the Brazilian semiarid region and is an important center for irrigated fruit growing. This region is responsible for 97% of the national exportation of table grapes, including seedless grapes. Based on the
Adriana Mayumi Yano-Melo, Aguín O., Anaya A.L., Bengtsson J., Bettiol W., Bhattacharyya P., Bradford M.M., Brundrett M.C, Cheng X., Cochran W.G., De-Polli H., Debosz K., Dilly O., Douds Jr. D.D., Douds Jr. D.D., Feldmann F, Fernandes S.A.P., Fábio Sérgio Barbosa da Silva, Garcia C., Garcia C., Gerdemann J.W., Giovanetti M., Grisi B.M., Haynes R.J., Jeffries P., Jenkins W.R., Karagiannidis N., Leonor Costa Maia, Lovelock C.E., Lovelock C.E., Maia L.C., Marshall V.G., Matsuoka M., Miyauchi M.Y.H., Mohammad M.J., Monokrousos N., Monokrousos N., Mäder P., Nannipieri P., Natoniel Franklin de Melo, Nicácio de Oliveira Freitas, Noyd R.K., Oehl F., Pascual J.A., Pereira J.R., Pereira S.V., Purin S., Rillig M.C., Ryan M.H., Ryan M.H., Sampaio D.B., Sarangi P.K., Sattelmacher B., Schenck N.C., Schreiner R.P., Silva P.C.G., Souza R.G., Srivastava R., Stutz J.C., Swisher R., Taylor J.P., Truu M., Wardle D.A., Wright S.F., Yano-Melo A.M.   +64 more
core   +3 more sources

Radiation‐Resistant Bacteria Deinococcus radiodurans‐Derived Extracellular Vesicles as Potential Radioprotectors

Advanced Healthcare Materials, EarlyView.
Deinococcus radiodurans‐derived extracellular vesicles (R1‐EVs) provide radioprotection against total‐body irradiation‐induced acute radiation syndrome in mice. R1‐EVs mitigate oxidative damage by scavenging free radicals, promoting intestinal repair, enhancing hematopoietic function, and modulating immune responses. This study highlights the potential
Jeong Moo Han, Godfrey Mwiti, Seo‐Joon Yeom, Jaeyoon Lim, Woo Sik Kim, Sangyong Lim, Seung‐Taik Lim, Eui‐Baek Byun   +7 more
wiley   +1 more source

Enteropathogen survival in soil from different land-uses is predominantly regulated by microbial community composition [PDF]

, 2015
peer-reviewedMicrobial enteropathogens can enter the environment via landspreading of animal slurries and manures. Biotic interactions with the soil microbial community can contribute to their subsequent decay.
Brennan, Fiona P., Moynihan, Emma, Richards, Karl G., Ritz, Karl, Tyrrel, Sean   +4 more
core   +1 more source

TPMS‐Gyroid Scaffold‐Mediated Up‐Regulation of ITGB1 for Enhanced Cell Adhesion and Immune‐Modulatory Osteogenesis

Advanced Healthcare Materials, EarlyView.
A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang, Zenan Huang, Zhenzhong Han, Jing Luan, Zihan Li, Xutong Guo, Dongxu Yang, Yazhou Cui, Jinxiang Han, Duo Xu   +9 more
wiley   +1 more source