Results 81 to 90 of about 535,232 (307)

Scan-o-matic: High-Resolution Microbial Phenomics at a Massive Scale

G3: Genes, Genomes, Genetics, 2016
The capacity to map traits over large cohorts of individuals—phenomics—lags far behind the explosive development in genomics. For microbes, the estimation of growth is the key phenotype because of its link to fitness.
Martin Zackrisson, Johan Hallin, Lars-Göran Ottosson, Peter Dahl, Esteban Fernandez-Parada, Erik Ländström, Luciano Fernandez-Ricaud, Petra Kaferle, Andreas Skyman, Simon Stenberg, Stig Omholt, Uroš Petrovič, Jonas Warringer, Anders Blomberg   +13 more
doaj   +1 more source

Methods used in microbial forensics and epidemiological investigations for stronger health systems

Forensic Sciences Research, 2022
This review discusses microbial forensics as an emerging science that finds application in protecting human health. It is important to distinguish naturally acquired infections from those caused by the intentional release of microorganisms to the ...
Arizaldo E. Castro, Maria Corazon A. De Ungria   +1 more
doaj   +1 more source

A biophysical model of prokaryotic diversity in geothermal hot springs

, 2008
Recent field investigations of photosynthetic bacteria living in geothermal hot spring environments have revealed surprisingly complex ecosystems, with an unexpected level of genetic diversity.
A. J. Watson, A. L. Koch, Anna Klales, C. L. Lehman, D. de Beer, D. M. Ward, D. M. Ward, D. Tilman, Elizabeth Janus Nett, J. K. Kristjansson, J. M. Chase, James Duncan, M. J. Ferris, M. J. Ferris, M. J. Ferris, M. R. Droop, M. T. Madigan, R. F. Ramaley, R. W. Castenholz, S. C. Nold, S. M. Sievert, Suzanne Amador Kane, T. D. Brock, T. D. Brock   +23 more
core   +1 more source

Tunable cell differentiation via reprogrammed mating-type switching

Nature Communications
This study introduces a synthetic biology approach that reprograms the yeast mating-type switching mechanism for tunable cell differentiation, facilitating synthetic microbial consortia formation and cooperativity. The underlying mechanism was engineered
Yu Chyuan Heng, Shohei Kitano, Adelia Vicanatalita Susanto, Jee Loon Foo, Matthew Wook Chang   +4 more
doaj   +1 more source

Synthetic control of a fitness tradeoff in yeast nitrogen metabolism

Journal of Biological Engineering, 2009
Background Microbial communities are involved in many processes relevant to industrial and medical biotechnology, such as the formation of biofilms, lignocellulosic degradation, and hydrogen production. The manipulation of synthetic and natural microbial
Lee Jack J, Beisel Chase L, Hoff Kevin G, Bayer Travis S, Smolke Christina D   +4 more
doaj   +1 more source

Spatial organization of the kelp microbiome at micron scales

Microbiome, 2022
Background Elucidating the spatial structure of host-associated microbial communities is essential for understanding taxon-taxon interactions within the microbiota and between microbiota and host. Macroalgae are colonized by complex microbial communities,
S. Tabita Ramírez-Puebla, Brooke L. Weigel, Loretha Jack, Cathleen Schlundt, Catherine A. Pfister, Jessica L. Mark Welch   +5 more
doaj   +1 more source

Identifying Keystone Species in the Human Gut Microbiome from Metagenomic Timeseries using Sparse Linear Regression

, 2014
Human associated microbial communities exert tremendous influence over human health and disease. With modern metagenomic sequencing methods it is possible to follow the relative abundance of microbes in a community over time.
Fisher, Charles K., Mehta, Pankaj
core   +3 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Probiotic modulation of symbiotic gut microbial–host metabolic interactions in a humanized microbiome mouse model

Molecular Systems Biology, 2008
The transgenomic metabolic effects of exposure to either Lactobacillus paracasei or Lactobacillus rhamnosus probiotics have been measured and mapped in humanized extended genome mice (germ‐free mice colonized with human baby flora).
Francois‐Pierre J Martin, Yulan Wang, Norbert Sprenger, Ivan K S Yap, Torbjörn Lundstedt, Per Lek, Serge Rezzi, Ziad Ramadan, Peter van Bladeren, Laurent B Fay, Sunil Kochhar, John C Lindon, Elaine Holmes, Jeremy K Nicholson   +13 more
doaj   +1 more source

Synthetic microbial ecosystems : an exciting tool to understand and apply microbial communities [PDF]

, 2013
Many microbial ecologists have described the composition of microbial communities in a plenitude of environments, which has greatly improved our basic understanding of microorganisms and ecosystems.
Boon, Nico, De Roy, Karen, Marzorati, Massimo, Van de Wiele, Tom, Van den Abbeele, Pieter   +4 more
core   +2 more sources