Structural basis for the assembly of the Ragulator-Rag GTPase complex
mTORC1 activity is controlled through Rag GTPases, which are anchored to the lysosome through the Ragulator. Here, the authors give molecular insights into Ragulator-Rag GTPase assembly and present the crystal structures of the Ragulator alone and in ...
Ryo Yonehara +12 more
doaj +1 more source
Arabi lambs (n =28; body weight = 24 ± 3.7 kg; average age = 120 ± 8 days) were used to investigate the effect of microbial additives on growth performance, microbial protein synthesis and rumen microbial population of fattening lamb based on completely ...
E. Direkvandi +2 more
semanticscholar +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Improving the yield of rumen microbial protein (MCP) has significant importance in the promotion of animal performance and the reduction of protein feed waste.
Zhongyan Lu +4 more
semanticscholar +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Metabolism of soluble proteins by rumen microorganisms and the influence of condensed tannins on nitrogen solubility and degradation [PDF]
The amino acid requirements of ruminants are met by two sources; microbes leaving the rumen and dietary protein escaping fermentation in the rumen. Much ruminant research has therefore focused on improving amino acid supply to the duodenum by increasing ...
Hedqvist, Helena
core
Genomic blueprints of sponge-prokaryote symbiosis are shared by low abundant and cultivatable Alphaproteobacteria [PDF]
Marine sponges are early-branching, filter-feeding metazoans that usually host complex microbiomes comprised of several, currently uncultivatable symbiotic lineages.
Cox, Cymon +6 more
core +4 more sources
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
The evaluation of metabolizable protein content of some indigenous feedstuffs used in ruminant nutrition [PDF]
Aim: To determine the metabolizable protein (MP) content of common indigenous feedstuffs used in ruminant nutrition using in situ method. Materials and Methods: Nine ruminant feeds such as maize grain (MG), groundnut cake (GNC), mustard oilcake (MOC ...
Lalatendu Keshary Das +3 more
doaj +1 more source
Influence of ruminal degradable intake protein restriction on characteristics of digestion and growth performance of feedlot cattle during the late finishing phase. [PDF]
Two trials were conducted to evaluate the influence of supplemental urea withdrawal on characteristics of digestion (Trial 1) and growth performance (Trial 2) of feedlot cattle during the last 40 days on feed.
Calderon, Jose F +7 more
core +1 more source

