Site Selective Antibody-Oligonucleotide Conjugation via Microbial Transglutaminase. [PDF]
Nucleic Acid Therapeutics (NATs), including siRNAs and AntiSense Oligonucleotides (ASOs), have great potential to drug the undruggable genome. Targeting siRNAs and ASOs to specific cell types of interest has driven dramatic improvement in efficacy and ...
Cui, Xianshu +6 more
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Effects of Replacing Dry-rolled Corn with Increasing Levels of Corn Dried Distillers Grains with Solubles on Characteristics of Digestion, Microbial Protein Synthesis and Digestible Energy of Diet in Hair Lambs Fed High-concentrate Diets. [PDF]
Four male lambs (Katahdin; average live weight 25.9±2.9 kg) with "T" type cannulas in the rumen and proximal duodenum were used in a 4×4 Latin square experiment to evaluate the influence of supplemental dry distillers grain with solubles (DDGS) levels (0,
Barreras, A +9 more
core +3 more sources
Markers for Quantifying Microbial Protein Synthesis in the Rumen
Measurement of ruminal microbial protein is necessary to quantify ruminal escape of dietary protein and microbial yields. Microbial markers used most widely have been the internal markers, diaminopimelic acid and nucleic acids (RNA, DNA, individual purines and pyrimidines, or total purines), and the external isotopic markers (e.g., 15N and 35S ...
G A, Broderick, N R, Merchen
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This study investigated the effectiveness of the urine sample collection method in predicting the volume urinary and synthesis of microbial nitrogen. Eight fistulated steers were used with accessible rumens and kept in individual stalls.
Laila Cecília Ramos Bendia +8 more
doaj +3 more sources
Rendered-protein hydrolysates for microbial synthesis of cyanophycin biopolymer
Cyanophycin is a poly(arginyl-aspartate) biopolymer produced and stored intracellularly by bacteria. Cyanophycin has been proposed as a renewable replacement for petrochemical-based industrial products. An abundant source of amino acids and nitrogen such as in the form of protein hydrolysates is needed for the biosynthesis of cyanophycin.
Daniel K Y, Solaiman +4 more
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A rumen simulation technique (Rusitec) apparatus with eight 800 ml fermentation vessels was used to investigate the effects of rumen degradable protein (RDP) level and non-fibre carbohydrate (NFC) type on ruminal fermentation, microbial growth, and ...
Xiang H. Zhao +7 more
doaj +1 more source
L-arginine metabolism as pivotal interface of mutual host–microbe interactions in the gut
L-arginine (L-arg) is a versatile amino acid and a central intestinal metabolite in mammalian and microbial organisms. Thus, L-arg participates as precursor of multiple metabolic pathways in the regulation of cell division and growth. It also serves as a
Björn Nüse +4 more
doaj +1 more source
Applications of protein engineering in the microbial synthesis of plant triterpenoids
Triterpenoids are a class of natural products widely used in fields related to medicine and health due to their biological activities such as hepatoprotection, anti-inflammation, anti-viral, and anti-tumor. With the advancement in biotechnology, microorganisms have been used as cell factories to produce diverse natural products. Despite the significant
Yan Luo +4 more
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Enzymatic Synthesis of Protein Hydrolysates From Animal Proteins: Exploring Microbial Peptidases [PDF]
Instituto de Biociencias Letras e Ciencias Exatas Universidade Estadual Paulista Julio de Mesquita Filho (UNESP)
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Unusual Metabolism and Hypervariation in the Genome of a Gracilibacterium (BD1-5) from an Oil-Degrading Community. [PDF]
The candidate phyla radiation (CPR) comprises a large monophyletic group of bacterial lineages known almost exclusively based on genomes obtained using cultivation-independent methods.
Andersen, Gary L +7 more
core +2 more sources

