Results 191 to 200 of about 150,746 (328)

Novel Antifungal Scaffold Targeting Tubulin Overcomes Sclerotinia Sclerotiorum Resistance

Advanced Science, EarlyView.
Addressing pesticide resistance, novel chromone‐acylhydrazone hybrids targeting fungal tubulin are synthesized. Compound G24 potently inhibited S. sclerotiorum (EC50 = 0.21µg mL−1) and demonstrated enhanced field performance via microencapsulation, offering a sustainable strategy against resistance and for global food security.
Lihui Shao, Xianqun Hu, Ying Wu, Xiang Zhou, Bo Zhang, Song Yang   +5 more
wiley   +1 more source

Regulation of Excitonic Behavior in Defective Acetylenic Polymers Enables Mechanism Switching in O2 Activation for Enhanced Water Decontamination

Advanced Science, EarlyView.
A molecular defect‐mediated charge accumulation strategy is developed to regulate the exciton behavior for selective molecular oxygen (O2)activation in poly(1,3,5‐triethynylbenzene) (PTEB). Artificial internal electric field (IEF) constructed in defective PTEB provides internal driving force to steer the directed migration of charge carriers, thereby ...
Xiaofeng Tang, Sijia Jin, Wei Li, Yingrong Wang, Haiyan Zhang, Zhiqiao He, Shuang Song, Yaqi Cai, Tao Zeng   +8 more
wiley   +1 more source

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

Advanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang, Mengqing Sun, Heng Dong, Xiaoting Zhang, Jingbo Zhang, Zhengguo Zhang, Mengjie Ni, Lina Li, Yunxin Pei, Xiaoyu Chen, Qian Li, Fangtian Bu, Jiacheng Huang, Liangyu Jiang, Zhuting Fang, Xuliang Chen, Jianxiang Chen, Yiting Qiao, Tian Xie   +18 more
wiley   +1 more source

Microbial diversity and toxin risk in tropical freshwater reservoirs of Cape Verde [PDF]

, 2018
Ana P. Semedo-Aguiar, José B. Pereira‐Leal, Ricardo B. Leite   +2 more
openalex   +1 more source

Remote Modulation of Single‐Atom Catalyst Boosts High‐Valent Cobalt–Oxo Species Generation for Water Purification and Detoxification

Advanced Science, EarlyView.
This study develops a phosphorus‐doped cobalt single‐atom catalyst that enhances high‐valent cobalt–oxo species generation for water purification. This atomic‐level tuning boosts the catalyst's activity by 3.5 times, enabling efficient pollutant degradation. A continuous‐flow reactor achieves high, long‐term removal efficiency, producing water with low
Wen‐Min Wang, Zheng‐Wei Yang, De‐Xiu Wu, Wen‐Long Wang, Qian‐Yuan Wu   +4 more
wiley   +1 more source

Correlation Between Microbial Toxin Levels and Biochemical Markers of Organ Damage in ICU Patients [PDF]

Harish Thummala, S. Sangeeta, Bhagyashree K Bhuyar, Likhith Sai Kiran Rapeti, Ramesh Kandimalla   +4 more
openalex   +1 more source

Food‐Activated Microneedle Sensor for Real‐Time, Colorimetric Spoilage Monitoring of Pre‐Packaged Food

Advanced Science, EarlyView.
A microneedle spoilage sensor for packaged food products is presented. The sensor is composed entirely of food‐derived agents, integrated together using a novel material processing approach. This resultant platform nondestructively reports spoilage state in real‐time through a colorimetric output.
Shadman Khan, Akansha Prasad, Mahum Javed, Roderick MacLachlan, Carlos D. M. Filipe, Tohid F. Didar   +5 more
wiley   +1 more source

The Silent Threat: Understanding Microbial Toxins and Their Global Impacts

Hafiza Arshi Saeed
openalex   +2 more sources

The Microbial Toxin Microcin B17: Prospects for the Development of New Antibacterial Agents

, 2019
Frédéric Collin, Anthony Maxwell
openalex   +1 more source

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

Advanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong, Ting Guo, Yi Huang, Yangchun Ma, Weijin Chen, Jie Xue, Jun Jiang, Enhui Dong, Yue Kong, Hang Ding, Wenlong Zhang, Shutao Ma   +11 more
wiley   +1 more source