Results 321 to 330 of about 1,010,901 (360)
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Studies of microbial toxins in Xenopus laevis oocytes
Experimental Cell Research, 1980Abstract Xenopus laevis oocytes have been incubated or microinjected with cholera and diphtheria holotoxins or their respective isolated fragments A and B. Effects on progesterone-induced maturation, protein synthesis and cAMP levels were observed. Xenopus laevis oocytes were highly susceptible to cholera toxin upon incubation as evidenced by the
Michel Schorderet +4 more
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Application of Microbial Toxins for Cancer Therapy [PDF]
, 2011 The principle of selective targeting of immunotoxins lies on the basis that cancer cells usually have few or specific growth factors/receptors/antigens highly over expressed on their surface. Ligands corresponding to these molecules are conjugated to modified toxins (modified to loss its native function) isolated form variety of bacterial populations ...
Mrudula Mathew +3 more
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Dietary Microbial Toxins and Type 1 Diabetes
Annals of the New York Academy of Sciences, 2003Abstract: Toxins may promote type 1 diabetes by modifying or damaging the β cell causing release of autoantigens. Streptomyces is a common soil bacterium that produces many toxic compounds. Some Streptomyces can infect vegetables, raising the possibility of dietary exposure to toxins. We aimed to identify toxins that erode cellular proton gradients in
Mark A. Myers +5 more
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Microbial toxins and the glycosylation of Rho family GTPases
Current Opinion in Structural Biology, 2000Large clostridial cytotoxins act on cells by glycosylating low molecular mass GTPases using nucleotide-sugars as the sugar donor. These toxins are important virulence factors in human and animal diseases, but are also valuable cell biology tools.
Busch, Christian, Aktories, Klaus
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Vacuolization of target cells: response to microbial toxins [PDF]
World Journal of Microbiology and Biotechnology, 2005 Vacuolization as a marker of microbial activity on cells is a well-known reaction. The phenomenon involves the formation of vacuoles in the cytoplasm of target cells followed by lysis, especially after the action of different cytotoxins. In this review we summarize data on microbial toxic products causing vacuolization of target cells in the light of ...
Jarosław Jóźwiak +2 more
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Microbial degradation and impact of Bracken toxin ptaquiloside on microbial communities in soil
Chemosphere, 2007The carcinogenic and toxic ptaquiloside (PTA) is a major secondary metabolite in Bracken fern (Pteridium aquilinum (L.) Kuhn) and was hypothesized to influence microbial communities in soil below Bracken stands. Soil and Bracken tissue were sampled at field sites in Denmark (DK) and New Zealand (NZ).
Engel, Pernille +4 more
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T lymphocyte-stimulating microbial toxins as ?superantigens?
Medical Microbiology and Immunology, 1991Infectious pathogens generally have to cope with the host's adaptive immune system, i.e., T and B lymphocytes. Common evasion mechanisms in this complex interaction are antigenic variations, the escape to immunologically priviledged sites or the use of immunosuppressive mechanisms.
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Detection of Microbial Toxins by -Omics Methods
2017Foodborne diseases caused by bacteria and their endotoxins and exotoxins hold enormous relevance for the public health sector, in particular in the context of the ever-growing globalization where proper monitoring and risk management approaches are still missing. Therefore, detection of bacteria and their exotoxins in food has been increasingly tackled
Rešetar Maslov, Dina +4 more
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Role of Toxins in Plant Microbial Interactions
1998Both plants and fungi produce a wide variety of low molecular weight natural products. Many of these compounds were once considered secondary metabolites with no particular biological role in the producing organism. Understanding the chemical interactions between plants and microorganisms can be complex and requires an integrated approach.
Susan P. McCormick +4 more
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