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American Journal of Physiology-Gastrointestinal and Liver Physiology, 2001
Clostridium difficile, the major etiologic factor of antibiotic-associated diarrhea and colitis, mediates its effects by releasing two large protein exotoxins, toxins A and B. A major toxin effect is related to the disassembly of actin microfilaments, leading to impairment of tight junctions in human colonocytes.
J. Thomas Lamont, Charalabos Pothoulakis
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Clostridium difficile, the major etiologic factor of antibiotic-associated diarrhea and colitis, mediates its effects by releasing two large protein exotoxins, toxins A and B. A major toxin effect is related to the disassembly of actin microfilaments, leading to impairment of tight junctions in human colonocytes.
J. Thomas Lamont, Charalabos Pothoulakis
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Evaluation of the Role of Probiotics As a New Strategy to Eliminate Microbial Toxins: a Review
Probiotics and Antimicrobial Proteins, 2022Abdolamir Ghadaksaz +4 more
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Microbial toxins, their functional role and phylogenetic validity
Biosystems, 1978Microbially produced toxins, which appear to lack a role in microbial survival, may be antimicrobial compounds of significance to the producers. These toxin/antibiotics may act against cell metabolism shared by man or animals and other microorganisms. Protein toxin/antibiotics are produced by single species of bacteria.
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Systems Biology: Integrating ‘‐Omics'‐Oriented Approaches to Determine Foodborne Microbial Toxins
, 2011The possible origins of microbial toxins vary widely, and detection of these toxins in different food matrices is a major challenge for food industries and regulatory agencies.
O. Singh, N. Nagaraj, P. Gabani
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Microbial Toxin Production: Opportunists and True Pathogens
Journal of Drug Metabolism & Toxicology, 2014A toxin is a poisonous substance produced within living cells or organisms. Toxins can be small molecules, peptides, or proteins that are capable of causing disease on contact with or absorption by body tissues interacting with biological macromolecules such as enzymes or cellular receptors.
Subha Ganguly, Ranjit Bordoloi
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Photorhabdus: A Microbial Factory of Insect-Killing Toxins
2015The overuse of chemical pesticides to meet the production and productivity goals in modern agriculture is causing a number of unintended side effects and destruction of the environment. Eco-friendly pest management techniques and strategies are urgently needed. Photorhabdus spp.
Jyoti Kushwah, Vishal Singh Somvanshi
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Microbial Surface Components and Toxins in Relation to Pathogenesis
1991I. Adhesion and Colonization.- Characterization and Surface Organization of E. coli Adhesins.- Binding of Enterobacterial Fimbria to Proteins of Basement Membranes and Connective Tissue - A Novel Function for Fimbriae.- P-Fimbriae: Molecular Aspects of Their Structure and Their Application as Carriers of Foreign Antigenic Determinants ...
Shlomo Rottem, Eliora Z. Ron
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