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Microbial transformation of alkaloids

Current Opinion in Microbiology, 2002
Alkaloids continue to provide mankind with a plethora of medicines, poisons and potions. Because many valuable drugs are derived from such natural compounds, there is much interest in their transformation to provide new compounds or intermediates for the synthesis of new or improved drugs.
Neil C Bruce
exaly   +3 more sources

Microbial Transformation of Mesterolone

Chemistry & Biodiversity, 2005
AbstractThe microbial transformation of mesterolone (=(1α,5α,17β)‐17‐hydroxy‐1‐methylandrostan‐3‐one; 1), by a number of fungi yielded (1α,5α)‐1‐methylandrostane‐3,17‐dione (2), (1α,3β,5α,17β)‐1‐methylandrostane‐3,17‐diol (3), (5α)‐1‐methylandrost‐1‐ene‐3,17‐dione (4), (1α,5α,15α)‐15‐hydroxy‐1‐methylandrostane‐3,17‐dione (5), (1α,5α,6α,17β)‐6,17 ...
M. Iqbal Choudhary   +6 more
openaire   +2 more sources

Microbial transformation of prednisone

Natural Product Research, 2005
The microbial transformation of prednisone (17alpha,21-dihydroxy-pregna-1,4-diene-3,11,20-trione) (1) by Cunninghamella elegans afforded two metabolites, 17alpha,21-dihydroxy-5alpha-pregn-1-ene-3,11,20-trione (2) and 17alpha,20S,21-trihydroxy-5alpha-pregn-1-ene-3,11-dione (3), while the fermentation of 1 with Fusarium lini, Rhizopus stolonifer and ...
M Iqbal, Choudhary   +4 more
openaire   +2 more sources

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