Results 281 to 290 of about 8,071,557 (342)

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

open access: yesAnimal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke   +9 more
wiley   +1 more source

Biomarkers of Lupus Nephritis Histopathology: Where Do We Stand?

open access: yesArthritis &Rheumatology, EarlyView.
Objective Lupus nephritis (LN) is characterized by a variable disease course, necessitating continuous monitoring. There is an urgent need to identify noninvasive biomarkers. By reviewing and critically assessing the quality of existing studies on LN biomarkers correlating with histopathology, we here explore the challenges in promoting their use in ...
Valentina Querin   +11 more
wiley   +1 more source

Identification of histone deacetylase inhibitor targeting type I interferon and B‐cell abnormalities in systemic lupus erythematosus

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Systemic lupus erythematosus (SLE) is characterized by increased type I interferon (IFN‐I) and autoantibody production. This study aimed to identify drugs that can inhibit both IFN‐I and autoantibody production. Methods We identified an inhibitor of IFN‐I production from a chemical library.
Takehiro Hirayama   +16 more
wiley   +1 more source

Microbiological quality of different tea grades produced in diverse agro-climatic regions in Sri Lanka. [PDF]

open access: yesHeliyon
Karunaratne SHS   +3 more
europepmc   +1 more source

OGFRL1 deficiency causes CRMO via pathological osteoclastogenesis, with therapeutic response to TNF inhibitor

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives To verify the pathogenesis of the OGFRL1 loss‐of‐function variant (c.30del, p. F10Ffs*110) identified in a CRMO patient and investigate the underlying mechanism. Methods Whole exome sequencing and Sanger sequencing were performed to identify and confirm the variant.
Wen Xiong   +9 more
wiley   +1 more source

A gamified formative question bank to enhance student learning and engagement in a foundational medical science course

open access: yesAnatomical Sciences Education, EarlyView.
Abstract While gamified learning platforms show promise for engaging digital learners and promoting active learning, evidence of their effectiveness in predicting academic outcomes remains limited. This study examined how engagement patterns and incentives impact academic outcomes in a gamified environment to determine whether a formative question bank
Mohammad Aldalou   +5 more
wiley   +1 more source

Curriculum to career: A qualitative study of pathologists' assistant graduates' experiences

open access: yesAnatomical Sciences Education, EarlyView.
Abstract The field of pathologists' assistants (PathAs) has evolved significantly, with formal education programs now playing a crucial role in professional training. This study explores the educational experiences of PathA graduates in Canada, focusing on how accredited programs prepare students for professional practice.
Leeying Lau, Jina J. Y. Kum
wiley   +1 more source

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