Results 261 to 270 of about 204,627 (333)

Image analysis method for measurement and prediction of intra‐matrix IgG diffusion

open access: yesBiotechnology Progress, EarlyView.
Experimental and image analysis workflow for b‐IgG diffusion in hyaluronic acid (HA) matrix. Abstract Measurement and imaging of intra‐matrix protein therapeutics diffusion is important due to the emergence of injectable biologics currently in various stages of research and clinical testing.
Riya Debbarma   +2 more
wiley   +1 more source

Optimizing sterile filtration of nanoemulsions through proper choice of prefilter properties

open access: yesBiotechnology Progress, EarlyView.
Abstract Nanoemulsions, with droplet sizes between 20 and 200 nm, have emerged as a promising vaccine adjuvant and drug delivery system, enhancing the solubility of hydrophobic drugs for diverse applications. Sterile filtration of nanoemulsions is particularly challenging due to the similar size between the nanodroplets and the 0.2 μm nominal pore size
Shreya Kapila   +4 more
wiley   +1 more source

Significance, clinical spectrum, and microbiological evaluation of Actinomyces blood stream infections. [PDF]

open access: yesIJID Reg
Ali M   +6 more
europepmc   +1 more source

Artificial intelligence and machine learning‐assisted digital applications for biopharmaceutical manufacturing

open access: yesBiotechnology Progress, EarlyView.
Abstract Artificial intelligence and automation are no longer just buzzwords in the biopharmaceutical industry. The manufacturing of a class of biologics, comprising monoclonal antibodies, cell therapies, and gene therapies, is far more complex than that of traditional small molecule drugs.
Shyam Panjwani, Hao Wei, John Mason
wiley   +1 more source

Effect of cell retention techniques in Komagataella phaffii lab‐scale continuous processes

open access: yesBiotechnology Progress, EarlyView.
Abstract Perfusion technologies play a growing role in the implementation of continuous processes for biotherapeutics production in mammalian‐based manufacturing. However, their application to alternative production hosts is limited. Cell retention systems are of key importance for the efficiency of perfusion bioreactors.
Marina Y. Linova   +5 more
wiley   +1 more source

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