Results 141 to 150 of about 2,028,087 (333)
NSP7 Molecular Degrader Attenuates Coronaviral Infection Through the β‐TrCP1/FBXO5 Axis
Advanced Science, EarlyView.Host E3 ligase FBXO5 as a key regulator that promotes K48‐linked ubiquitination and proteasomal degradation of SARS‐CoV‐2 NSP7, thereby suppressing viral replication. NSP7 ubiquitination is co‐regulated by β‐TrCP1 and TAF1. Small molecule BC24877 disrupts β‐TrCP1‐mediated degradation of FBXO5, stabilizing FBXO5 and enhancing NSP7 clearance ...
Yao Tong +18 more
wiley +1 more source
A Differential Microbiological Assay for Vitamin B12 and Pseudovitamin B1212 [PDF]
, 1956 D. Berman, H. Yacowitz, H. H. Weiser
openalex +1 more source
Advanced Science, EarlyView.The fabrication of ORL@Cu‐MOF and the mechanism of synergistic therapy by cuproptosis, reprogram fatty acid metabolism and anti‐PD‐1. Abstract Lymph node metastasis (LNM) is one of the significant characteristics of poor prognosis in oral squamous cell carcinoma (OSCC), strongly associated with high mortality rates.
Zi‐Zhan Li +11 more
wiley +1 more source
MECHANISM OF THE MICROBIOLOGICAL OXIDATION OF AMMONIA. PART I. FORMATION OF INTERMEDIATE PRODUCTS. [PDF]
, 1938 Wenbo Rao +2 more
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Advanced Science, EarlyView.Acute respiratory distress syndrome (ARDS) is a severe lung condition with limited treatments, often triggered by overactive endothelial cells (ECs). It is identified that macrophage‐derived secretory autophagosomes (MSAPs) exacerbate lung damage by activating EC function.
Xing‐xing Zhu +17 more
wiley +1 more source
Advanced Science, EarlyView.This study extensively characterizes the B cell response of rainbow trout (Oncorhynchus mykiss) in response to red mark syndrome (RMS). This disease, suspected to be caused by a Midichloria‐like organism (MLO), induces skin lesions in the infected animals, characterized by a massive influx of IgM+ B cells.
J Germán Herranz‐Jusdado +10 more
wiley +1 more source