Results 81 to 90 of about 4,737,444 (281)

Modelling production ramp-up of engineering products [PDF]

, 2010
Companies that introduce new products quickly have been shown to be better performers. The effectiveness of the new product introduction process is critical to their performance. Production ramp-up is a necessary phase of new product introduction, and
Roberts, S., Ball, Peter D., Scorzafave, C., S Roberts, P D Ball, C Scorzafave, Natalicchio, A., A Natalicchio, Roberts S., Natalicchio A., Scorzafave C., Ball P. D.   +11 more
core   +1 more source

Frequent Sweetened Beverage Consumption Is Associated With Accelerated Biological Aging: Evidence From a Population‐Based Study and Gut Microbiota Analysis

Advanced Science, EarlyView.
Frequent sweetened beverage consumption is associated with accelerated biological aging in a large Chinese population. Five gut microbial genera are consistently enriched in both frequent sweetened beverage consumers and individuals with accelerated aging and show significant mediating effects, suggesting a potential microbiota‐related pathway linking ...
Yuwei Shi, Xinmei Li, Yufan Hao, Qiaoyu Wu, Yuji Yu, Siyu Li, Nuo Xu, Yi‐Hsuan Wu, Eunhye Lee, Chi Chang, Emily Hu, Ying Lu, Elizabeth Delzell, Ann W. Hsing, Shankuan Zhu   +14 more
wiley   +1 more source

Airway Microbiome; Allergy, Asthma

, 2016
The rate at which the prevalence of allergy keeps rising globally poses a threat to health and economic development.Various parts of the immune system are involved in this process and some delineated genetic and environmental factors seem to contribute ...
Bashir, Maryam
core  

Cobalt Single‐Atom Nanozyme for Enhanced Intestinal Radioprotection and Tumor Radiosensitization via Bidirectional ROS Modulation

Advanced Science, EarlyView.
Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Shengqi Yin, Junjie Li, Yishu Zou, Yang Liu, Yilin Zheng, Lu Yu, Wanying Zheng, Yajun Zou, Zehui Zhang, Tao Li, Peiqun Yin, Jianlin Zhang, Yuen Wu, Yi Ding   +13 more
wiley   +1 more source

Unveiling the rhizosphere microbiome of Dendrobium: mechanisms, microbial interactions, and implications for sustainable agriculture

Frontiers in Microbiology
The rhizosphere microbiome plays a critical role in plant health and productivity by fostering beneficial microbial interactions that support nutrient cycling, stress tolerance, and disease suppression.
Surendra Sarsaiya, Surendra Sarsaiya, Archana Jain, Ranjan Singh, Qihai Gong, Qin Wu, Jishuang Chen, Jingshan Shi, Jingshan Shi   +8 more
doaj   +1 more source

Intermittent Fasting Restores Cardiac Lipid Homeostasis in Diabetic Cardiomyopathy in Association With Akkermansia Muciniphila and 1‐methyl‐L‐histidine

Advanced Science, EarlyView.
Intermittent fasting reshapes the gut microbiota in diabetic cardiomyopathy, restoring Akkermansia muciniphila and the microbiota‐associated metabolite 1‐methyl‐L‐histidine. This shift is linked to improved cardiac lipid homeostasis, reduced lipid peroxidation, and attenuated myocardial injury, highlighting a gut microbiota–metabolite–lipid axis in ...
Kaiyuan Jiang, Fen Xiong, Yiwen Peng, Lingfei Meng, Xinran Wang, Yingruo Xu, Tian Tang, Hongchang Gao   +7 more
wiley   +1 more source

Gut microbiome engineering with probiotics: current trends and future directions

Discover Applied Sciences
The human gut microbiome plays a crucial role in digestion, immunity and overall health. Recent advancements in microbiome engineering have led to the development of engineered probiotics, offering new therapeutic possibilities for various health ...
Priti Duhan, Bhupesh Gupta, Mujtaba Ahmed, Poonam Bansal   +3 more
doaj   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

A new method for extracting skin microbes allows metagenomic analysis of whole-deep skin [PDF]

, 2013
In the last decade, an extensive effort has been made to characterize the human microbiota, due to its clinical and economic interests. However, a metagenomic approach to the skin microbiota is hampered by the high proportion of host DNA that is ...
Francesc Calafell, Koldo Garcia-Etxebarria, Garcia-Etxebarria, Koldo, Marc Garcia-Garcerà (3214074), Mireia Coscollà (149823), Calafell, Francesc, Amparo Latorre (88013), Calafell, Francesca, Garcia-Garcerà, Marc, Koldo Garcia-Etxebarria (461325), Coscollà, Mireia, Marc Garcia-Garcerà, Amparo Latorre, Francesc Calafell (148375), Latorre, Amparo, Mireia Coscollà   +15 more
core   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

Advanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal, Ubaid Tariq, Shreya Mehrotra, Saravanan Matheshwaran, Jan Marsal, Ashok Kumar   +5 more
wiley   +1 more source