Results 1 to 10 of about 24,111 (211)

MICROBODIES IN EXPERIMENTALLY ALTERED CELLS [PDF]

open access: bronzeThe Journal of Cell Biology, 1967
A rapid and sustained increase in the number of microbodies in liver and kidney cells can be induced in male rats by ethyl chlorophenoxyisobutyrate (CPIB), a hypolipidemic drug. This phenomenon permits investigation of several aspects of microbody behavior in experimental conditions.
D, Svoboda, H, Grady, D, Azarnoff
  +7 more sources

Characterisation of a secreted MFSD6-Fc microbody as a decoy receptor for respiratory enterovirus D68Research in context [PDF]

open access: yesEBioMedicine
Summary: Background: Enterovirus D68 (EV-D68) is a prominent non-polio enterovirus known to cause severe respiratory infections and poliomyelitis-like illnesses in children.
Zhaoxue Li   +10 more
doaj   +2 more sources

Checkpoint inhibitor-expressing lentiviral vaccine suppresses tumor growth in preclinical cancer models [PDF]

open access: yesJournal for ImmunoTherapy of Cancer
Background While immunotherapy has been highly successful for the treatment of some cancers, for others, the immune response to tumor antigens is weak leading to treatment failure. The resistance of tumors to checkpoint inhibitor therapy may be caused by
Thomas D Norton   +3 more
doaj   +2 more sources

AeiA, an Atg8-interacting protein in Aspergillus oryzae, promotes peroxisome degradation by pexophagy [PDF]

open access: yesAutophagy Reports, 2023
There are two types of autophagy, non-selective (bulk) autophagy, in which substrates are randomly incorporated into autophagosomes, and selective autophagy, in which substrates are specifically targeted.
Takashi Kikuma, Joichiro Nishio
doaj   +2 more sources

LOCALIZATION OF ENZYMES WITHIN MICROBODIES [PDF]

open access: bronzeThe Journal of Cell Biology, 1973
Microbodies from rat liver and a variety of plant tissues were osmotically shocked and subsequently centrifuged at 40,000 g for 30 min to yield supernatant and pellet fractions. From rat liver microbodies, all of the uricase activity but little glycolate oxidase or catalase activity were recovered in the pellet, which probably contained the crystalline
A H, Huang, H, Beevers
openaire   +3 more sources

Microbodies in experimentally altered cells. IX. The fate of microbodies.

open access: greenThe American journal of pathology, 1972
Male rats were given 0.25% CPIB (ethyl chlorophenoxyisobutyrate) for 4 weeks at which time their liver cells showed the typical increase in number of microbodies (peroxisomes). During the first week after withdrawal of CPIB and simultaneous injection of allylisopropylacetamide (AIA), an inhibitor of catalase synthesis, the microbody matrix, in ...
D, Svoboda, J, Reddy
openaire   +3 more sources

Isolation of Microbodies from Plant Tissues [PDF]

open access: bronzePlant Physiology, 1971
Specialized microbodies have previously been isolated and characterized from fatty seedling tissues (glyoxysomes) and leaves (leaf peroxisomes). We have now examined 11 other plant tissues, including tubers, fruits, roots, shoots, and petals, and find that all contain particulate catalase, a distinctive common enzyme component of microbodies. On linear
A H, Huang, H, Beevers
openaire   +4 more sources

SARS CoV-2 Nucleoprotein Enhances the Infectivity of Lentiviral Spike Particles

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
The establishment of SARS CoV-2 spike-pseudotyped lentiviral (LV) systems has enabled the rapid identification of entry inhibitors and neutralizing agents, alongside allowing for the study of this emerging pathogen in BSL-2 level facilities.
Tarun Mishra   +5 more
doaj   +1 more source

The Glyoxysomal Protease LON2 Is Involved in Fruiting-Body Development, Ascosporogenesis and Stress Resistance in Sordaria macrospora

open access: yesJournal of Fungi, 2021
Microbodies, including peroxisomes, glyoxysomes and Woronin bodies, are ubiquitous dynamic organelles that play important roles in fungal development. The ATP-dependent chaperone and protease family Lon that maintain protein quality control within the ...
Antonia Werner   +4 more
doaj   +1 more source

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