An ACE2 Microbody Containing a Single Immunoglobulin Fc Domain Is a Potent Inhibitor of SARS-CoV-2 [PDF]
Cell Reports, 2020 Soluble forms of angiotensin-converting enzyme 2 (ACE2) have recently been shown to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
Chen, Jennifer S. +9 more
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AeiA, an Atg8-interacting protein in Aspergillus oryzae, promotes peroxisome degradation by pexophagy [PDF]
Autophagy Reports, 2023 There are two types of autophagy, non-selective (bulk) autophagy, in which substrates are randomly incorporated into autophagosomes, and selective autophagy, in which substrates are specifically targeted.
Takashi Kikuma, Joichiro Nishio
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Checkpoint inhibitor-expressing lentiviral vaccine suppresses tumor growth in preclinical cancer models [PDF]
Journal for ImmunoTherapy of CancerBackground While immunotherapy has been highly successful for the treatment of some cancers, for others, the immune response to tumor antigens is weak leading to treatment failure. The resistance of tumors to checkpoint inhibitor therapy may be caused by
Thomas D Norton +3 more
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Characterisation of a secreted MFSD6-Fc microbody as a decoy receptor for respiratory enterovirus D68Research in context [PDF]
EBioMedicineSummary: Background: Enterovirus D68 (EV-D68) is a prominent non-polio enterovirus known to cause severe respiratory infections and poliomyelitis-like illnesses in children.
Zhaoxue Li +10 more
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Microbody of Methanol-Grown Yeasts [PDF]
European Journal of Biochemistry, 1975 Profuse appearance of microbodies was observed in the cells of methanol‐utilizing yeasts in connection with the enhanced catalase activity. These microbodies were isolated successfully by means of sucrose gradient centrifugation from the methanol‐grown cells of Kloeckera sp. no. 2201.
S. Fukui +5 more
semanticscholar +3 more sources
Hansenula polymorpha: An attractive model organism for molecular studies of peroxisome biogenesis and function [PDF]
, 1992 In wild-type Hansenula polymorpha the proliferation of peroxisomes is induced by various unconventional carbon- and nitrogen sources. Highest induction levels, up to 80% of the cytoplasmic volume, are observed in cells grown in methanol-limited chemostat
Harder, W., +3 more
core +29 more sources
POSSIBLE PROPERTIES OF MICROBODIES (PEROXISOMES) MICROBODY PROLIFERATION AND HYPOLIPIDEMIC DRUGS [PDF]
Journal of Histochemistry & Cytochemistry, 1973 J. Reddy
semanticscholar +4 more sources
SARS CoV-2 Nucleoprotein Enhances the Infectivity of Lentiviral Spike Particles
Frontiers in Cellular and Infection Microbiology, 2021 The establishment of SARS CoV-2 spike-pseudotyped lentiviral (LV) systems has enabled the rapid identification of entry inhibitors and neutralizing agents, alongside allowing for the study of this emerging pathogen in BSL-2 level facilities.
Tarun Mishra +5 more
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Journal of Fungi, 2021 Microbodies, including peroxisomes, glyoxysomes and Woronin bodies, are ubiquitous dynamic organelles that play important roles in fungal development. The ATP-dependent chaperone and protease family Lon that maintain protein quality control within the ...
Antonia Werner +4 more
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Frontiers in Pharmacology, 2021 Background: Hirudin has been widely used in the treatment of antifibrosis. Previous studies have shown that hirudin can effectively improve the clinical remission rate of chronic kidney disease. However, the mechanism of its renal protection has not been
Hang-Xing Yu +18 more
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