Explicit consideration of topological and parameter uncertainty gives new insights into a well-established model of glycolysis [PDF]
Previous models of glycolysis in the sleeping sickness parasite Trypanosoma brucei assumed that the core part of glycolysis in this unicellular parasite is tightly compartimentalized within an organelle, the glycosome, which had previously been shown to ...
Achcar +30 more
core +1 more source
Reprogramming Hansenula polymorpha for penicillin production: expression of the Penicillium chrysogenum pcl gene [PDF]
We aim to introduce the penicillin biosynthetic pathway into the methylotrophic yeast Hansenula polymorpha. To allow simultaneous expression of the multiple genes of the penicillin biosynthetic pathway, additional markers were required.
Gidijala, Loknath, +3 more
core +2 more sources
To reveal the mechanical characteristics and damage evolution mechanism of limestone in the bending process, the cumulative acoustic emission (AE) hits were used to define the damage variable, and the rock microbody hypothesis and the Weibull ...
Yuanshuai Zhang +4 more
doaj +1 more source
Cloning and analysis of cathepsin B gene of Radopholus similis
The banana burrowing nematode, Radopholus similis, is a migratory endoparasite plant nematode and severely harms many tropical and subtropical crops. It is the most important invasive species to banana worldwide, and is listed as a quarantine pest in ...
LI Danlei +4 more
doaj +1 more source
Busca de inibidores da enzima glicossomal gliceraldeído 3-fosfato desidrogenase de Trypanosoma cruzi [PDF]
The inhibitory activity of crude extracts of Meliaceae and Rutaceae plants on glycosomal glyceraldehyde-3-phosphate dehydrogenase (gGAPDH) enzyme from Trypanosoma cruzi was evaluated at 100 μg/mL.
AMBROZIN, Alessandra R. P. +9 more
core +1 more source
2-pentanone production from hexanoic acid by Penicillium roqueforti from blue cheese:is this the pathway used in humans? [PDF]
Production of 2-pentanone, a methylketone, is increased in fasting ketotic humans. Its origin is unknown. We hypothesised that it is formed via β-oxidation of hexanoic acid by the peroxisomal pathway proposed for methylketone-producing fungi and yeasts ...
Mills, Graham A., Walker, Valerie
core +2 more sources
Microbodies: peroxisomes and glyoxysomes. [PDF]
Microbodies were first reported at the ultrastructural level in the proximal convoluted tubule ofmouse kidney by Rhodin in 1954 (1) and in hepatic parenchymal cells by Rouiller and Bernhard in 1956 (2) at about the time The Journal of Cell Biology was established .
N E, Tolbert, E, Essner
openaire +2 more sources
Differential remodelling of peroxisome function underpins the environmental and metabolic adaptability of diplonemids and kinetoplastids [PDF]
The remodelling of organelle function is increasingly appreciated as a central driver of eukaryotic biodiversity and evolution. Kinetoplastids including Trypanosoma and Leishmania have evolved specialized peroxisomes, called glycosomes.
Bringaud, Frédéric +15 more
core +4 more sources
Cytosolic enzymes with a mitochondrial ancestry from the anaerobic chytrid Piromyces sp. E2 [PDF]
The anaerobic chytrid Piromyces sp. E2 lacks mitochondria, but contains hydrogen-producing organelles, the hydrogenosomes. We are interested in how the adaptation to anaerobiosis influenced enzyme compartmentalization in this organism.
Akhmanova, A.S. (Anna) +5 more
core +1 more source
Fossil melanosomes or bacteria? A wealth of findings favours melanosomes:Melanin fossilises relatively readily, bacteria rarely, hence the need for clarification in the debate over the identity of microbodies in fossil animal specimens [PDF]
The discovery of fossil melanosomes has resulted in a wealth of research over the last 7 years, notably the reconstruction of colour in dinosaurs and fossil mammals.
Barden +54 more
core +2 more sources

