Results 51 to 60 of about 25,031 (244)

Cobalt Single‐Atom Intercalation in Molybdenum Disulfide Enhances Piezocatalytic and Enzyodynamic Activities for Advanced Cancer Therapeutics

open access: yesAdvanced Science, Volume 12, Issue 14, April 10, 2025.
The single‐atom doped molybdenum disulfide piezocatalyst markedly enhances both piezoelectric and enzyme‐mimicking activities, accelerating glutathione depletion. It induces mitochondrial dysfunction and cell cycle arrest, ultimately driving apoptosis while inactivating glutathione peroxidase 4 to initiate ferroptosis.
Haomiao Bai   +8 more
wiley   +1 more source

Knocking out the carboxyltransferase interactor 1 (CTI1) in Chlamydomonas boosted oil content by fivefold without affecting cell growth

open access: yesPlant Biotechnology Journal, Volume 23, Issue 4, Page 1230-1242, April 2025.
Summary The first step in chloroplast de novo fatty acid synthesis is catalysed by acetyl‐CoA carboxylase (ACCase). As the rate‐limiting step for this pathway, ACCase is subject to both positive and negative regulation. In this study, we identify a Chlamydomonas homologue of the plant carboxyltransferase interactor 1 (CrCTI1) and show that this protein
Zhongze Li   +8 more
wiley   +1 more source

Indicators of replicative damage in equine tendon fibroblast monolayers [PDF]

open access: yes, 2013
<p>Background: Superficial digital flexor tendon (SDFT) injuries of horses usually follow cumulative matrix microdamage; it is not known why the reparative abilities of tendon fibroblasts are overwhelmed or subverted.
David L Becker   +4 more
core   +1 more source

Ferroptosis‐Related Genes Are Effective Markers for Diagnostic Targets of Crohn's Disease

open access: yesImmunity, Inflammation and Disease, Volume 13, Issue 3, March 2025.
We found decreased serum iron and ferritin levels in CD patients compared to healthy controls. Combined detection of ferroptosis‐related genes is of great value in the diagnosis of CD, with the specificity even reaching 100%. The expression levels of these ferroptosis‐related genes are related to M0 macrophages, mast cells resting, and neutrophil ...
Pengfei Liu   +4 more
wiley   +1 more source

Role of aconitase in plant stress response and signaling

open access: yesPhysiologia Plantarum, Volume 177, Issue 1, January/February 2025.
Abstract Mitochondria are the centres of carbon and energy metabolism in cells and are functionally integrated with other organelles. Under environmental stress, disturbances in organellar functions trigger stress signals that activate the necessary metabolic responses and maintain cell redox homeostasis.
Moona Rahikainen   +4 more
wiley   +1 more source

Subcellular localization of monoglyceride acyltransferase, xanthine oxidation, NADP: isocitrate dehydrogenase and alkaline phosphatase in the mucosa of the guinea-pig small intestine. [PDF]

open access: yes, 1980
1. Rate dependent and isopycnic banding in a zonal rotor were used to analyse the subcellular sites of enzymes in homogenates of guinea-pig small intestinal mucosa.
Connock, Martin J.   +2 more
core   +1 more source

Isolation of Microbodies from Plant Tissues [PDF]

open access: yesPlant Physiology, 1971
Specialized microbodies have previously been isolated and characterized from fatty seedling tissues (glyoxysomes) and leaves (leaf peroxisomes). We have now examined 11 other plant tissues, including tubers, fruits, roots, shoots, and petals, and find that all contain particulate catalase, a distinctive common enzyme component of microbodies. On linear
Anthony H. C. Huang, Harry Beevers
openaire   +2 more sources

Reactive Oxygen Species (ROS) and Antioxidant Systems in Enhancing Plant Resilience Against Abiotic Stress

open access: yesInternational Journal of Agronomy, Volume 2025, Issue 1, 2025.
Reactive oxygen species (ROS) are central to plant responses under abiotic stress, acting as both damaging agents and signaling molecules. This study explores the balance between ROS production, oxidative damage, and the antioxidant defense mechanisms in plants.
Amin Fathi   +10 more
wiley   +1 more source

Structure, kinetic characterization and subcellular localization of the two ribulose 5-phosphate epimerase isoenzymes from Trypanosoma cruzi [PDF]

open access: yes, 2017
The enzyme of the pentose phosphate pathway (PPP) ribulose-5-phosphate-epimerase (RPE) is encoded by two genes present in the genome of Trypanosoma cruzi CL Brener clone: TcRPE1 and TcRPE2. Despite high sequence similarity at the amino acid residue level,
Cazzulo, Juan Jose   +4 more
core   +6 more sources

Unlocking Wheat Drought Tolerance: The Synergy of Omics Data and Computational Intelligence

open access: yesFood and Energy Security, Volume 13, Issue 6, November/December 2024.
ABSTRACT Currently, approximately 4.5 billion people in developing countries consider bread wheat (Triticum aestivum L.) as a staple food crop, as it is a key source of daily calories. Wheat is, therefore, ranked the second most important grain crop in the developing world. Climate change associated with severe drought conditions and rising global mean
Marlon‐Schylor Le Roux   +3 more
wiley   +1 more source

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