Results 91 to 100 of about 19,813 (281)

Enzymatic microbubble robots

Nature Nanotechnology
The development of micro- and nanorobots has amplified the demand for intelligent multifunctional machines in biomedical applications, but most microrobotic systems struggle to achieve the attributes needed for those applications. Here we introduce enzymatic microbubble robots that exhibit steerable motion, enhanced biodegradability, high in vivo ...
Songsong Tang, Hong Han, Xiaotian Ma, Payal N. Patel, Chen Gong, Junhang Zhang, Ernesto Criado-Hidalgo, Jounghyun Yoo, Jiahong Li, Gwangmook Kim, Shukun Yin, Di Wu, Mikhail G. Shapiro, Qifa Zhou, Wei Gao   +14 more
openaire   +2 more sources

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

Angewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Bioeconomy, sustainability, and digital technologies in Haematococcus lacustris biomass and astaxanthin production: advances and outlook

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Astaxanthin is a carotenoid with strong antioxidant properties, used in research on cancer treatment, ocular injuries, and neurological disorders. When produced by the microalgae Haematococcus lacustris, its antioxidant potential is even higher than that of the synthetic molecule, making it particularly attractive for pharmaceutical and ...
Renata Kühl Rocha, Lucas Nascimento Dario, Ana Caroline de Souza Barnabé, Paulo Sérgio de Arruda Ignácio, Reinaldo Gaspar Bastos, Augusto Ducati Luchessi   +5 more
wiley   +1 more source

Spectral Imaging for Microbubble Characterization

Langmuir, 2019
Microbubbles stabilized by an outer lipid shell have been studied extensively for both diagnostic and therapeutic applications. The shell composition can significantly influence microbubble behavior, but performing quantitative measurements of shell properties is challenging.
Richard J. Browning, Miles Aron, Anna Booth, Paul Rademeyer, Sarah Wing, Veerle Brans, Shamit Shrivastava, Dario Carugo, Eleanor Stride   +8 more
openaire   +5 more sources

Scale‐Down Platforms for Process‐Oriented Enzyme Screening Using Microfluidics

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Enzyme screening platforms are typically evaluated based on their throughput and analytical performance rather than their ability to mimic the conditions encountered at large scale. In bioreactors, enzymes experience gradients in substrate concentration, oxygen availability, pH, temperature, and interfacial exposure, caused by imperfect mixing
Maria I. Rodriguez‐Torres, Elif Erdem, Junhyeong Wang, Ulrich Krühne, Michael Daniele, John M. Woodley   +5 more
wiley   +1 more source

Enhanced cavitation dose and reactive oxygen species production in microbubble-mediated sonodynamic therapy for inhibition of Escherichia coli and biofilm

Ultrasonics Sonochemistry
Sonodynamic therapy (SDT) is an emerging antibacterial therapy. This work selected hematoporphyrin monomethyl ether (HMME) as the sonosensitizer, and studied the enhanced inhibition effect of Escherichia coli and biofilm by microbubble-mediated ...
Changlong Li, Fengmeng Teng, Fengmin Wu, Hui Zhang, Chunbing Zhang, Dong Zhang   +5 more
doaj   +1 more source

Enhancement of High-Intensity Focused Ultrasound Heating by Short-Pulse Generated Cavitation

Applied Sciences, 2017
A target tissue can be thermally coagulated in high-intensity focused ultrasound (HIFU) treatment noninvasively. HIFU thermal treatments have been clinically applied to various solid tumors. One of the problems in HIFU treatments is a long treatment time.
Shin Yoshizawa, Ryo Takagi, Shin-ichiro Umemura   +2 more
doaj   +1 more source

Quercetin‐zinc coordination polymer coated CaCO3 nanoparticles potentiate radiotherapy through reprogramming tumor immunosuppression

BMEMat, EarlyView.
Synthesis of QZCaCO3‐PEG to synergistically enhance the immunogenicity of radiotherapy through concurrent Zn2+‐induced cancer cell pyroptosis and Que‐mediated hypoxia amelioration through sequentially suppressing TGF‐β secretion and ECM deposition. Abstract Radiotherapy has demonstrated broad applications in treating solid tumors, but the hostile tumor
Chunjie Wang, Hengze Ding, Yu Hao, Honglin An, Ziliang Dong, Minming Chen, Yujie Zhu, Quguang Li, Bin Huang, Liangzhu Feng   +9 more
wiley   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

Therapeutic Potential of Manuka Honey Microbubble Dressing in Wound Management

Advanced Materials Interfaces
This study investigates the antibacterial effects of Manuka honey (MH) microbubbles on Staphylococcus aureus (S. aureus) in wound dressings. MH solutions are passed through a microbubble generator with a high‐density stainless steel mesh nozzle to ...
Pei‐Ju Lin
doaj   +1 more source