Results 101 to 110 of about 11,678 (233)

Multivalent Bi‐Specific Nanoerythrosomes: A Two‐Birds‐One‐Stone Approach to Combine Homologous and Active Targeting for Effective Thrombolysis

Small, EarlyView.
A multivalent bi‐specific nanoerythrosome (mBiNE@tPA) is developed as a “two‐birds‐one‐stone” platform that simultaneously exploits two principal thrombus components. By integrating erythrocyte membrane‐mediated homologous targeting with cRGD‐based active targeting to activated platelets, mBiNE@tPA achieves enhanced thrombus accumulation, triggered ...
Yu Huang, Yilin Yang, Nicole Henry, Boram Gu, Jiahua Wang, Yuanyuan Guo, Colin Longstaff, Simon A. Thom, Yuehua Li, Xiao Yun Xu, Rongjun Chen   +10 more
wiley   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

VIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe, Satish Rojekar, Amol Gholap, K. Navaneetha Pandiyaraj, Mukesh Patekar, Claudia Riccardi, R. R. Deshmukh, Tomáš Kovářík, Kalim Deshmukh   +8 more
wiley   +1 more source

In vitro Ultrasonic Potentiation of 2-Phenylethynesulfonamide/Magnetic Fluid Hyperthermia Combination Treatments for Ovarian Cancer

International Journal of Nanomedicine, 2020
Fernando Mérida, 1 Carlos Rinaldi, 2, 3 Eduardo J Juan, 4 Madeline Torres-Lugo 1 1Department of Chemical Engineering, University of Puerto Rico-Mayagüez, Mayagüez, Puerto Rico; 2Department of Chemical Engineering, University of Florida,
Mérida F, Rinaldi C, Juan EJ, Torres-Lugo M   +3 more
doaj  

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Diffusion of Characteristic Gases in Oil‐Immersed Transformer by Computational Fluid Dynamics Simulation and Experimental Verification

High Voltage, EarlyView.
ABSTRACT The complex diffusion of characteristic gases within oil‐immersed transformers significantly influences the timeliness between the fault occurrence and gas detection. So far, the gas transport processes and spatio‐temporal distributions remain inadequately understood.
Chunpeng Li, Yuan Li, Jianyi Wang, Zhengqin Zhou, Zhihao Liu, Zhiqiu Chen, Dongyang Zheng, Guanjun Zhang   +7 more
wiley   +1 more source

Pleiotropic Roles of FBXO11 in Tumorigenesis: Implications for Targeted Therapy

Cancer Science, EarlyView.
This complex comprises of scaffold CUL1, SKP1, RBX1 and FBXO11 receptor. The substrate is phosphorylated by specific kinase enzyme and recognized by the substrate recognition domain. FBXO11 targets numerous substrates for ubiquitination and degradation, FBXO11 substrates mainly include Snail, ZEB1, p53, BCL6, CDT2, CIITA, Cdc25a, hnRNPA2B1, SAMD1 and ...
Yuqi Zhang, Changyi Fan, Shiheng Chen, Tianyue Lu, Yuanyuan Li, Feng Du, Shanshan Wang   +6 more
wiley   +1 more source

L‐Glutamine Plus L‐Glutamic Acid Enhances Antioxidant Status and Ammonia Toxicity Resilience, Upregulates Interleukin IL‐10 Gene, and Improves Gut Microbiota and Survival in Juvenile Nile Tilapia

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Glutamine (Gln) and glutamic acid (Glu) are the most abundant free amino acids (AAs) in the fish body. Although classified as non‐essential AAs, their supplementation can be a strategy to optimize the growth performance and health of fish.
Cristiana Leonor da Silva Carneiro, Thaís Pereira da Cruz, Larissa Cassemiro Pacheco Monteiro, Larissa Glugoski, Mariana Vieira Feldhaus, Leandro Cavalcante Lipinski, Marcelo Ricardo Vicari, Viviane Nogaroto, Valéria Rossetto Barriviera, Wilson Massamitu Furuya   +9 more
wiley   +1 more source

Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders

Oral Diseases, EarlyView.
ABSTRACT Objective Salivary gland hypofunction and xerostomia represent major clinical complications of radiation therapy, autoimmune disorders such as Sjögren's disease, and inherited epithelial ion transport defects. This review integrates current knowledge on ion channel dysfunction as a central mechanistic driver of salivary gland pathology and ...
Tarek Mohamed Abd El‐Aziz, Shankara N. Varadarajan, Viktor Drel, Prakash Arullampalam, Mahmoud I. Shoulkamy, Ahmed Al‐Sabi, Brij B. Singh   +6 more
wiley   +1 more source

Active Electromagnetic Interference Suppression for MRI and Proton Resonance Frequency Shift Thermometry During MRI‐Guided Microwave Ablation

Magnetic Resonance in Medicine, Volume 96, Issue 4, Page 1572-1588, October 2026.
ABSTRACT Purpose To develop a software‐based active electromagnetic interference (EMI) suppression (AES) framework on whole‐body multi‐channel MRI systems for reliable MRI and MR thermometry during MRI‐guided microwave ablation (MWA). Methods In addition to primary imaging coils, an unloaded standard body array coil was positioned outside the imaging ...
Qing Dai, Jason Chiang, Shu‐Fu Shih, Wenqi Zhou, David S. K. Lu, Holden H. Wu   +5 more
wiley   +1 more source

Bubble‐Mediated Intensification of Biomass‐Based Oil Conversion: Bubble Dynamics, Control Strategies and Equipment

Carbon and Hydrogen, Volume 28, Issue 3, Page 320-339, September 2026.
Focus on the bubble interface transfer behavior during the conversion process of biomass‐based oil, and mainly review the bubble dynamic characteristics in the gas‐solid/gas‐liquid reaction processes under extreme conditions during the conversion process.
Zhenghao Yang, Jiajia Li, Yong Yu, Zhibin Zhou, Benshuai Guo, Yulong Chang, Jianping Li, Xia Jiang   +7 more
wiley   +1 more source