Results 131 to 140 of about 19,813 (281)
ABSTRACT The complex diffusion of characteristic gases within oil‐immersed transformers significantly influences the timeliness between the fault occurrence and gas detection. So far, the gas transport processes and spatio‐temporal distributions remain inadequately understood.
Chunpeng Li +7 more
wiley +1 more source
Pleiotropic Roles of FBXO11 in Tumorigenesis: Implications for Targeted Therapy
This complex comprises of scaffold CUL1, SKP1, RBX1 and FBXO11 receptor. The substrate is phosphorylated by specific kinase enzyme and recognized by the substrate recognition domain. FBXO11 targets numerous substrates for ubiquitination and degradation, FBXO11 substrates mainly include Snail, ZEB1, p53, BCL6, CDT2, CIITA, Cdc25a, hnRNPA2B1, SAMD1 and ...
Yuqi Zhang +6 more
wiley +1 more source
Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders
ABSTRACT Objective Salivary gland hypofunction and xerostomia represent major clinical complications of radiation therapy, autoimmune disorders such as Sjögren's disease, and inherited epithelial ion transport defects. This review integrates current knowledge on ion channel dysfunction as a central mechanistic driver of salivary gland pathology and ...
Tarek Mohamed Abd El‐Aziz +6 more
wiley +1 more source
Microbubble generation for PIV seeding
A new device for microbubble generation using small-scale unsteady cavitation of supersaturated water is presented. Cavitation is created in a radial diffuser with a directed outlet for inlet/saturation pressures ranging from 300 to 1000 kPa.
Paul Brandner (14732326) +3 more
core
Abstract figure legend Temporal scaling physiology differs significantly between mice and humans. Mice have higher metabolism, heart and respiratory rate, as well as faster blood flow rates, brain activity and physiological dynamics over time. These differences influence the temporal resolution needed in preclinical imaging of mouse models to ...
Sara Gargiulo, Matteo Gramanzini
wiley +1 more source
Clustered regularly interspaced short palindromic repeat (CRISPR) is transforming Huntington's disease research through allele‐selective huntingtin (HTT) targeting, transcriptional and RNA suppression, and advanced disease modelling. Progress towards precision therapy depends on safe central nervous system (CNS) delivery, reduced off‐target and immune ...
Kairat Zhakipbekov +11 more
wiley +1 more source
Study of a Frugal Design Picosecond Laser System for Laser‐Assisted Corneal Surgery
Stromal surface after extraction of the lamella cut with the studied frugal picosecond laser source. ABSTRACT Femtosecond lasers have long been the gold standard for corneal laser‐assisted surgery, but their high cost limits widespread use. This study challenges their supremacy by investigating a cost‐effective alternative: a frugal all‐fiber ...
Maxime Quirke +9 more
wiley +1 more source
ABSTRACT Purpose To develop a software‐based active electromagnetic interference (EMI) suppression (AES) framework on whole‐body multi‐channel MRI systems for reliable MRI and MR thermometry during MRI‐guided microwave ablation (MWA). Methods In addition to primary imaging coils, an unloaded standard body array coil was positioned outside the imaging ...
Qing Dai +5 more
wiley +1 more source
Custom-Built Vision-Assisted Arc Discharge System for Fabricating High-Q In-Line Microbubble Resonator Arrays. [PDF]
Ma Y +6 more
europepmc +1 more source
ABSTRACT Background Midline catheters (MCs) are increasingly utilized as an alternative to peripheral and central venous catheters. However, the lack of standardized protocols for tip location and confirmation methods remains a significant barrier to patient safety and clinical decision‐making.
Jieyu Wang +9 more
wiley +1 more source

