Results 11 to 20 of about 29,238 (342)

Optical microbubble resonator [PDF]

Optics Letters, 2010
We develop a method for fabricating very small silica microbubbles having a micrometer-order wall thickness and demonstrate the first optical microbubble resonator. Our method is based on blowing a microbubble using stable radiative CO(2) laser heating rather than unstable convective heating in a flame or furnace.
Sumetsky, M., Dulashko, Y., Windeler, R.S.   +2 more
openaire   +3 more sources

Optical Whispering-Gallery-Mode Microbubble Sensors

Micromachines, 2022
Whispering-gallery-mode (WGM) microbubble resonators are ideal optical sensors due to their high quality factor, small mode volume, high optical energy density, and geometry/design/structure (i.e., hollow microfluidic channels).
Xuyang Zhao, Zhihe Guo, Yi Zhou, Junhong Guo, Zhiran Liu, Yuxiang Li, Man Luo, Xiang Wu   +7 more
doaj   +2 more sources

Analysis of the Uncertainty in Microbubble Characterization [PDF]

Ultrasound in Medicine & Biology, 2016
There is increasing interest in the use of microbubble contrast agents for quantitative imaging applications such as perfusion and blood pressure measurement. The response of a microbubble to ultrasound excitation is, however, extremely sensitive to its size, the properties of its coating and the characteristics of the sound field and surrounding ...
Harfield, C, Fury, CR, Memoli, G, Jones, P, Ovenden, N, Stride, E   +5 more
core   +7 more sources

Methods for Rapid Characterization of Tunable Microbubble Formulations

Bioengineering
To optimize microbubble formulations for clinical applications, the size distribution, concentration, and acoustic intensity must be rapidly measurable to allow for the successful iteration of microbubble design. In this paper, a comprehensive method was
Savannah L. Harpster, Alexandra M. Piñeiro, Joyce Y. Wong   +2 more
doaj   +2 more sources

Dependence of sonoporation efficiency on microbubble size: An in vitro monodisperse microbubble study

The Journal of the Acoustical Society of America, 2023
Sonoporation is the process where intracellular drug delivery is facilitated by ultrasound-driven microbubble oscillations. Several mechanisms have been proposed to relate microbubble dynamics to sonoporation including shear and normal stress. The present work aims to gain insight into the role of microbubble size on sonoporation by varying the ...
van Elburg, Benjamin, Deprez, Joke, van den Broek, Martin, De Smedt, Stefaan, Versluis, Michel, Lajoinie, Guillaume, Lentacker, Ine, Segers, Tim   +7 more
openaire   +5 more sources

Spectral Imaging for Microbubble Characterization

Langmuir, 2019
Microbubbles stabilized by an outer lipid shell have been studied extensively for both diagnostic and therapeutic applications. The shell composition can significantly influence microbubble behavior, but performing quantitative measurements of shell properties is challenging.
Richard J. Browning, Miles Aron, Anna Booth, Paul Rademeyer, Sarah Wing, Veerle Brans, Shamit Shrivastava, Dario Carugo, Eleanor Stride   +8 more
core   +8 more sources

Microbubble cavitation imaging [PDF]

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 2013
Ultrasound cavitation of microbubble contrast agents has a potential for therapeutic applications such as sonothrombolysis (STL) in acute ischemic stroke. For safety, efficacy, and reproducibility of treatment, it is critical to evaluate the cavitation state (moderate oscillations, stable cavitation, and inertial cavitation) and activity level in and ...
Vignon, F., Shi, W. T., Powers, J. E., Everbach, E. Carr, Liu, J. J., Gao, S. J., Xie, F., Porter, T. R.   +7 more
openaire   +3 more sources

Nonspherical ultrasound microbubbles

Proceedings of the National Academy of Sciences, 2023
Surface tension provides microbubbles (MB) with a perfect spherical shape. Here, we demonstrate that MB can be engineered to be nonspherical, endowing them with unique features for biomedical applications. Anisotropic MB were generated via one-dimensionally stretching spherical poly(butyl cyanoacrylate) MB above their glass transition temperature ...
Dasgupta, Anshuman, Sun, Tao, Palomba, Roberto, Rama, Elena, Zhang, Yongzhi, Power, Chanikarn, Moeckel, Diana, Liu, Mengjiao, Sarode, Apoorva, Weiler, Marek, Motta, Alessandro, Porte, Céline, Magnuska, Zuzanna, Said Elshafei, Asmaa, Barmin, Roman, Graham, Adam, McClelland, Arthur, Rommel, Dirk, Stickeler, Elmar, Kiessling, Fabian, Pallares, Roger M., De Laporte, Laura, Decuzzi, Paolo, McDannold, Nathan, Mitragotri, Samir, Lammers, Twan   +25 more
openaire   +2 more sources

Focal areas of increased lipid concentration on the coating of microbubbles during short tone-burst ultrasound insonification. [PDF]

PLoS ONE, 2017
Acoustic behavior of lipid-coated microbubbles has been widely studied, which has led to several numerical microbubble dynamics models that incorporate lipid coating behavior, such as buckling and rupture.
Klazina Kooiman, Tom van Rooij, Bin Qin, Frits Mastik, Hendrik J Vos, Michel Versluis, Alexander L Klibanov, Nico de Jong, Flordeliza S Villanueva, Xucai Chen   +9 more
doaj   +1 more source

Cardiovascular molecular imaging [PDF]

, 2013
Although there have been significant improvements in the treatment of cardiovascular diseases they still remain the main cause of morbidity and mortality globally. Currently available diagnostic approaches may not be adequate to detect pathologic changes
Khanicheh, Elham
core   +1 more source