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Microcephaly is defined as a head circumference more than two standard deviations below the mean for gender and age. Congenital microcephaly is present at birth, whereas postnatal microcephaly occurs later in life.
Emily Hanzlik, Joseph Gigante
doaj +5 more sources
Genomic Analysis of Korean Patient With Microcephaly
Microcephaly is a prevalent phenotype in patients with neurodevelopmental problems, often with genetic causes. We comprehensively investigated the clinical phenotypes and genetic background of microcephaly in 40 Korean patients.
Jiwon Lee +7 more
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BACKGROUND:In 2015, high rates of microcephaly were reported in Northeast Brazil following the first South American Zika virus (ZIKV) outbreak. Reported microcephaly rates in other Zika-affected areas were significantly lower, suggesting alternate causes
Oliver J Brady +18 more
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Zika and the Risk of Microcephaly.
(Abstracted from N Engl J Med 2016;375:1–4) During an outbreak in 2013–2014, the rate of Zika virus (ZIKV) infection in the Polynesian population was estimated at a rate of 66%, and it was estimated that it posed a risk of microcephaly in the first trimester of pregnancy of 0.95% (95% confidence interval [CI], 0.34%–1.91%).
M. Johansson +4 more
semanticscholar +4 more sources
Microcephaly epidemic related to the Zika virus and living conditions in Recife, Northeast Brazil
Background Starting in August 2015, there was an increase in the number of cases of neonatal microcephaly in Northeast Brazil. These findings were identified as being an epidemic of microcephaly related to Zika virus (ZIKV) infection.
Wayner Vieira de Souza +13 more
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Microcephaly, an etiopathogenic vision [PDF]
Microcephaly is defined by an occipital-frontal head circumference (OFD) 2 standard deviations (SD) smaller than the average expected for age, gender and population. Its incidence has been reported between 1.3 and 150 cases per 100,000 births. Currently,
Luis Eduardo Becerra-Solano +2 more
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Microcephaly in Neurometabolic Diseases [PDF]
Neurometabolic disorders are an important group of diseases that mostly occur in neonates and infants. They are mainly due to the lack or dysfunction of an enzyme or cofactors necessary for a specific biochemical reaction, which leads to a deficiency of ...
Wiktoria Kempińska +3 more
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Autosomal Recessive Primary Microcephaly: Not Just a Small Brain
Microcephaly or reduced head circumference results from a multitude of abnormal developmental processes affecting brain growth and/or leading to brain atrophy.
S. Zaqout, A. Kaindl
semanticscholar +1 more source
Background Brain development during embryogenesis and in early postnatal life is particularly complex and involves the interplay of many cellular processes and molecular mechanisms, making it extremely vulnerable to exogenous insults, including ionizing ...
T. Jaylet +13 more
semanticscholar +1 more source

