Results 201 to 210 of about 90,161 (348)

Congenital Zika Virus Infection: Beyond Neonatal Microcephaly.

JAMA Neurology, 2017
A. Melo, R. S. Aguiar, M. Amorim, M. Arruda, F. O. Melo, Suelem Taís Clementino Ribeiro, A. G. M. Batista, Thales A. Ferreira, Mayra Pereira Dos Santos, Virgínia Vilar Sampaio, Sarah Rogéria Martins Moura, L. P. Rabello, Clarissa Emanuelle Gonzaga, G. Malinger, R. Ximenes, Patrícia Soares de Oliveira-Szejnfeld, F. Tovar-Moll, L. Chimelli, P. Silveira, Rodrigo Delvechio, L. Higa, L. Campanati, R. Nogueira, A. M. Filippis, J. Szejnfeld, C. Voloch, O. Ferreira, R. Brindeiro, A. Tanuri   +28 more
semanticscholar   +2 more sources

Genetic complexity in pediatric onset epilepsy‐movement disorder syndromes: Insights from a cohort of 97 subjects

Epilepsia, EarlyView.
Abstract Objective Conditions presenting with both epilepsy and movement disorders (EPIMDs) range from relatively benign cases to severe developmental encephalopathies. However, the full clinical and genetic spectrum still needs to be better defined.
Davide Caputo, Roberta Solazzi, Barbara Castellotti, Celeste Panteghini, Francesca Luisa Sciacca, Elisa Visani, Elena Freri, Francesca Ragona, Laura Canafoglia, Federica Zibordi, Giovanna Zorzi, Shari Gandelli, Cinzia Gellera, Silvana Franceschetti, Nardo Nardocci, Tiziana Granata   +15 more
wiley   +1 more source

Further Delineation of Phenotype and Genotype of Primary Microcephaly Syndrome with Cortical Malformations Associated with Mutations in the WDR62 Gene [PDF]

, 2021
Ryszard Ślężak, Robert Śmigiel, Ewa Obersztyn, Agnieszka Pollak, Mateusz Dawidziuk, Wojciech Wiszniewski, Monika Bekiesińska‐Figatowska, Małgorzata Rydzanicz, Rafał Płoski, Paweł Gawliński   +9 more
openalex   +1 more source

Zika Virus Disrupts Neural Progenitor Development and Leads to Microcephaly in Mice.

Cell Stem Cell, 2016
Cui Li, Dan Xu, Qing Ye, Shuai Hong, Yisheng Jiang, Xinyi Liu, N. Zhang, Lei Shi, C. Qin, Zhiheng Xu   +9 more
semanticscholar   +1 more source

Meta‐analysis of genetic mapping studies in mice reveals candidate epilepsy modifier genes that are outside the current drug development landscape

Epilepsia, EarlyView.
Abstract Objective Despite decades of development in anti‐seizure medications, ~30% of individuals remain refractory to all treatments, and none of the existing therapies are disease modifying. Identifying targets outside the current preclinical paradigm is critically important.
Giovanna L. Durante, Anna L. Tyler, Rod C. Scott, Amanda E. Hernan, J. Matthew Mahoney   +4 more
wiley   +1 more source

Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids

Cell Reports Medicine, 2020
Guoqiang Sun, F. Chiuppesi, Xianwei Chen, Cheng Wang, E. Tian, Jenny Nguyen, Mindy Kha, Daniel Trinh, Han Zhang, M. Marchetto, Hongjun Song, G. Ming, F. Gage, D. Diamond, Felix Wussow, Yanhong Shi   +15 more
semanticscholar   +1 more source

EHD4 and ASAP2 are critical negative regulators of the claudin‐5‐based endothelial barrier

The FEBS Journal, EarlyView.
Cell‐surface CLDN‐5 protein levels can be evaluated using a probe that can bind to the extracellular domains of CLDN‐5. A probe derived from Clostridium perfringens enterotoxin allows us to isolate cells with high CLDN‐5 protein levels from a knockout cell library.
Yosuke Hashimoto, Gergő Porkoláb, Natalie Hudson, Jeffrey O'Callaghan, Nicole Hanley, Conor Delaney, Mária A. Deli, Peter Westenskow, Matthew Campbell   +8 more
wiley   +1 more source

Giants in the cold: Morphological evidence for vascular heat retention in the viscera but not the skeletal muscle of the basking shark (Cetorhinus maximus)

Journal of Fish Biology, EarlyView.
Abstract Fewer than 50 of the over 30,000 extant species of fishes have developed anatomical specializations facilitating endothermy in specific body regions. The plankton‐feeding basking shark (Cetorhinus maximus), traditionally classified as an ectotherm, was recently shown to have regionally endothermic traits such as centralized red muscle (RM ...
C. Antonia Klöcker, Axel Schlindwein, Martin C. Arostegui, Ingrid M. Bruvold, Joel V. Wernström, Montserrat Martin‐Armas, David W. Sims, Nicolas Straube, Andreas Altenburger, Claudia Junge   +9 more
wiley   +1 more source

Antipsychotic Use Among Intellectually Disabled Individuals With Rare Genetic Variants That Confer Risk for Schizophrenia

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Rare genetic variation can predispose individuals to the development of schizophrenia, with certain genes and copy number variants (CNVs) conferring risk at the exome/genome‐wide level. Despite this strong association, little is known about antipsychotic effectiveness and tolerability among individuals with most of these disorders ...
Mark Ainsley Colijn
wiley   +1 more source

Abordagem da Terapia Ocupacional a bebês com microcefalia: uma experiência do estágio curricular / An occupational therapy approach to babies with microcephaly: an experiment in curricular internship [PDF]

, 2018
Jamine Cunha dos Reis, Patrícia da Silva Santos, Mayara Francelle Oliveira Barata, Ilka Veras Falcão   +3 more
openalex   +1 more source